The TOTEM collaboration at the CERN LHC has measured the differential cross-section of elastic proton–proton scattering at
s
=
8
TeV
in the squared four-momentum transfer range
0.2
GeV
2
<
|
t
|
<
...1.9
GeV
2
. This interval includes the structure with a diffractive minimum (“dip”) and a secondary maximum (“bump”) that has also been observed at all other LHC energies, where measurements were made. A detailed characterisation of this structure for
s
=
8
TeV
yields the positions,
|
t
|
dip
=
(
0.521
±
0.007
)
GeV
2
and
|
t
|
bump
=
(
0.695
±
0.026
)
GeV
2
, as well as the cross-section values,
d
σ
/
d
t
dip
=
(
15.1
±
2.5
)
μ
b
/
GeV
2
and
d
σ
/
d
t
bump
=
(
29.7
±
1.8
)
μ
b
/
GeV
2
, for the dip and the bump, respectively.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
•Clusters of microcalcifications can be considered as early signs of breast cancer.•A three phases approach is proposed: preprocessing-detection-clustering.•Application of circular Hough Transform ...for microcalcification detection.•The proposed method reached a sensitivity of 91.78
Microcalcification clusters in mammograms can be considered as early signs of breast cancer. However, their detection is a very challenging task because of different factors: large variety of breast composition, highly textured breast anatomy, impalpable size of microcalcifications in some cases, as well as inherent low contrast of mammograms. Thus, the need to support the clinicians’ work with an automatic tool.
In this work a three-phases approach for clustered microcalcification detection is presented. Specifically, it is made up of a pre-processing step, aimed at highlighting potentially interesting breast structures, followed by a single microcalcification detection step, based on Hough transform, that is able to grasp the innate characteristic shape of the structures of interest. Finally, a cluster identification step to group microcalcifications is carried out by means of a clustering algorithm able to codify expert domain rules.
The detection performance of the proposed method has been evaluated on 364 mammograms of 182 patients obtaining a true positive ratio of 91.78% with 2.87 false positives per image.
Experimental results demonstrated that the proposed method is able to detect microcalcification clusters in digital mammograms showing performance comparable to different methodologies exploited in the state-of-art approaches, with the advantage that it does not require any training phase and a large set of data. The performance of the proposed approach remains high even for more difficult clinical cases of mammograms of young women having high-density breast tissue thus resulting in a reduced contrast between microcalcifications and surrounding dense tissues.
Breast cancer is the main cause of female malignancy worldwide. Effective early detection by imaging studies remains critical to decrease mortality rates, particularly in women at high risk for ...developing breast cancer. Breast Magnetic Resonance Imaging (MRI) is a common diagnostic tool in the management of breast diseases, especially for high-risk women. However, during this examination, both normal and abnormal breast tissues enhance after contrast material administration. Specifically, the normal breast tissue enhancement is known as background parenchymal enhancement: it may represent breast activity and depends on several factors, varying in degree and distribution in different patients as well as in the same patient over time. While a light degree of normal breast tissue enhancement generally causes no interpretative difficulties, a higher degree may cause difficulty to detect and classify breast lesions at Magnetic Resonance Imaging even for experienced radiologists. In this work, we intend to investigate the exploitation of some statistical measurements to automatically characterize the enhancement trend of the whole breast area in both normal and abnormal tissues independently from the presence of a background parenchymal enhancement thus to provide a diagnostic support tool for radiologists in the MRI analysis.
Abstract
The TOTEM collaboration at the CERN LHC has measured the differential cross-section of elastic proton–proton scattering at
$$\sqrt{s} = 8\,\mathrm{TeV}$$
s
=
8
TeV
in the squared ...four-momentum transfer range
$$0.2\,\mathrm{GeV^{2}}< |t| < 1.9\,\mathrm{GeV^{2}}$$
0.2
GeV
2
<
|
t
|
<
1.9
GeV
2
. This interval includes the structure with a diffractive minimum (“dip”) and a secondary maximum (“bump”) that has also been observed at all other LHC energies, where measurements were made. A detailed characterisation of this structure for
$$\sqrt{s} = 8\,\mathrm{TeV}$$
s
=
8
TeV
yields the positions,
$$|t|_{\mathrm{dip}} = (0.521 \pm 0.007)\,\mathrm{GeV^2}$$
|
t
|
dip
=
(
0.521
±
0.007
)
GeV
2
and
$$|t|_{\mathrm{bump}} = (0.695 \pm 0.026)\,\mathrm{GeV^2}$$
|
t
|
bump
=
(
0.695
±
0.026
)
GeV
2
, as well as the cross-section values,
$$\left. {\mathrm{d}\sigma /\mathrm{d}t}\right| _{\mathrm{dip}} = (15.1 \pm 2.5)\,\mathrm{{\mu b/GeV^2}}$$
d
σ
/
d
t
dip
=
(
15.1
±
2.5
)
μ
b
/
GeV
2
and
$$\left. {\mathrm{d}\sigma /\mathrm{d}t}\right| _{\mathrm{bump}} = (29.7 \pm 1.8)\,\mathrm{{\mu b/GeV^2}}$$
d
σ
/
d
t
bump
=
(
29.7
±
1.8
)
μ
b
/
GeV
2
, for the dip and the bump, respectively.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
The proton–proton elastic differential cross section
d
σ
/
d
t
has been measured by the TOTEM experiment at
s
=
2.76
TeV
energy with
β
∗
=
11
m
beam optics. The Roman Pots were inserted to 13 times ...the transverse beam size from the beam, which allowed to measure the differential cross-section of elastic scattering in a range of the squared four-momentum transfer (|
t
|) from 0.36 to
0.74
GeV
2
. The differential cross-section can be described with an exponential in the |
t
|-range between 0.36 and
0.54
GeV
2
, followed by a diffractive minimum (dip) at
|
t
dip
|
=
(
0.61
±
0.03
)
GeV
2
and a subsequent maximum (bump). The ratio of the
d
σ
/
d
t
at the bump and at the dip is
1.7
±
0.2
. When compared to the proton–antiproton measurement of the D0 experiment at
s
=
1.96
TeV
, a significant difference can be observed. Under the condition that the effects due to the energy difference between TOTEM and D0 can be neglected, the result provides evidence for the exchange of a colourless C-odd three-gluon compound state in the
t
-channel of the proton–proton and proton–antiproton elastic scattering.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Abstract
The TOTEM collaboration has measured the elastic proton-proton differential cross section
$$\mathrm{d}\sigma /\mathrm{d}t$$
d
σ
/
d
t
at
$$\sqrt{s}=13$$
s
=
13
TeV LHC energy using ...dedicated
$$\beta ^{*}=90$$
β
∗
=
90
m beam optics. The Roman Pot detectors were inserted to 10
$$\sigma $$
σ
distance from the LHC beam, which allowed the measurement of the range 0.04 GeV
$$^{2}$$
2
; 4 GeV
$$^{2}$$
2
$$$$
in four-momentum transfer squared |
t
|. The efficient data acquisition allowed to collect about 10
$$^{9}$$
9
elastic events to precisely measure the differential cross-section including the diffractive minimum (dip), the subsequent maximum (bump) and the large-|
t
| tail. The average nuclear slope has been found to be
$$B=(20.40 \pm 0.002^{\mathrm{stat}} \pm 0.01^{\mathrm{syst}})~$$
B
=
(
20.40
±
0
.
002
stat
±
0
.
01
syst
)
GeV
$$^{-2}$$
-
2
in the |
t
|-range 0.04–0.2 GeV
$$^{2}$$
2
. The dip position is
$$|t_{\mathrm{dip}}|=(0.47 \pm 0.004^{\mathrm{stat}} \pm 0.01^{\mathrm{syst}})~$$
|
t
dip
|
=
(
0.47
±
0
.
004
stat
±
0
.
01
syst
)
GeV
$$^{2}$$
2
. The differential cross section ratio at the bump vs. at the dip
$$R=1.77\pm 0.01^{\mathrm{stat}}$$
R
=
1.77
±
0
.
01
stat
has been measured with high precision. The series of TOTEM elastic pp measurements show that the dip is a permanent feature of the pp differential cross-section at the TeV scale.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
This paper describes the design and the performance of the timing detector developed by the TOTEM Collaboration for the Roman Pots (RPs) to measure the Time-Of-Flight (TOF) of the protons produced in ...central diffractive interactions at the LHC . The measurement of the TOF of the protons allows the determination of the longitudinal position of the proton interaction vertex and its association with one of the vertices reconstructed by the CMS detectors. The TOF detector is based on single crystal Chemical Vapor Deposition (scCVD) diamond plates and is designed to measure the protons TOF with about 50 ps time precision. This upgrade to the TOTEM apparatus will be used in the LHC run 2 and will tag the central diffractive events up to an interaction pileup of about 1. A dedicated fast and low noise electronics for the signal amplification has been developed. The digitization of the diamond signal is performed by sampling the waveform. In conclusion, after introducing the physics studies that will most profit from the addition of these new detectors, we discuss in detail the optimization and the performance of the first TOF detector installed in the LHC in November 2015.
Introduction An important area in which an improvement of the imaging techniques would be extremely important, is the diagnosis of breast cancer. For this purpose, mammography is the principal ...diagnostic tool used. Although it is effective in the early detection of breast cancer, exists a real need for new automatic approaches that can improve the accuracy of detection of breast cancer in mammogram Images. In fact, a computerized system as a second reader can support the radiologist in the interpretation of these exams by reducing the number of false positives and thus, the biopsy procedures not necessary. Purpose In this paper, we propose a Computer Aided Detection System (CAD) for the microcalcification in mammogram images as a diagnostic support tool for radiologists in the analysis. Materials and methods We develop a fully automated tool for (1) pre-processing images using the edge detection process described by Canny which was designed to be an optimal edge detector according to particular criteria; (2) region of Interest extraction; (3) Adapted Hough Transform to identify the microcalcification cluster. The proposed method was evaluated using cases from publicly available mammography dataset such as Breast Cancer Digital Repository (BCDR) database. Results We present the results obtained in terms of accuracy, sensitivity, false positive for image. The proposed system shows results comparable state of the art. Conclusion The proposed method was advantageous in the identification of microcalcifications.
The TOTEM collaboration has measured the proton–proton total cross section at
s
=
13
TeV
with a luminosity-independent method. Using dedicated
β
∗
=
90
m
beam optics, the Roman Pots were inserted ...very close to the beam. The inelastic scattering rate has been measured by the T1 and T2 telescopes during the same LHC fill. After applying the optical theorem the total proton–proton cross section is
σ
tot
=
(
110.6
±
3.4
) mb, well in agreement with the extrapolation from lower energies. This method also allows one to derive the luminosity-independent elastic and inelastic cross sections:
σ
el
=
(
31.0
±
1.7
)
mb
and
σ
inel
=
(
79.5
±
1.8
)
mb
.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
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