After the launch of the Sentinel-5 Precursor satellite on 13 October 2017, its single payload, the TROPOspheric Monitoring Instrument (TROPOMI), was commissioned for 6 months. In this time the ...instrument was tested and calibrated extensively. During this phase the geolocation calibration was validated using a dedicated measurement zoom mode. With the help of spacecraft manoeuvres the solar angle dependence of the irradiance radiometry was calibrated for both internal diffusers. This improved the results that were obtained on the ground significantly. Furthermore the orbital and long-term stability was tested for electronic gains, offsets, non-linearity, the dark current and the output of the internal light sources. The CCD output gain of the UV, UVIS and NIR detectors shows drifts over time which can be corrected in the Level 1b (L1b) processor. In-flight measurements also revealed inconsistencies in the radiometric calibration and degradation of the UV spectrometer. Degradation was also detected for the internal solar diffusers. Since the start of the nominal operations (E2) phase in orbit 2818 on 30 April 2018, regularly scheduled calibration measurements on the eclipse side of the orbit are used for monitoring and updates to calibration key data. This article reports on the main results of the commissioning phase, the in-flight calibration and the instrument's stability since launch. Insights from commissioning and in-flight monitoring have led to updates to the L1b processor and its calibration key data. The updated processor is planned to be used for nominal processing from late 2020 on.
The Sentinel-5 Precursor satellite was successfully launched on 13 October 2017, carrying the Tropospheric Monitoring Instrument (TROPOMI) as its single
payload. TROPOMI is the next-generation ...atmospheric sounding instrument,
continuing the successes of GOME, SCIAMACHY, OMI, and OMPS, with higher
spatial resolution, improved sensitivity, and extended wavelength range. The
instrument contains four spectrometers, divided over two modules sharing a
common telescope, measuring the ultraviolet, visible, near-infrared, and
shortwave infrared reflectance of the Earth. The imaging system enables daily
global coverage using a push-broom configuration, with a spatial resolution
as low as 7×3.5 km2 in nadir from a Sun-synchronous orbit at
824 km and an Equator crossing time of 13:30 local solar time. This article reports the pre-launch calibration status of the TROPOMI payload
as derived from the on-ground calibration effort. Stringent requirements are
imposed on the quality of on-ground calibration in order to match the high
sensitivity of the instrument. A new methodology has been employed during the analysis of the obtained
calibration measurements to ensure the consistency and validity of the
calibration. This was achieved by using the production-grade Level 0 to 1b
data processor in a closed-loop validation set-up. Using this approach the
consistency between the calibration and the L1b product,
as well as confidence in the obtained calibration result, could be established. This article introduces this novel calibration approach and describes all
relevant calibrated instrument properties as they were derived before launch
of the mission. For most of the relevant properties compliance with the
calibration requirements could be established, including the knowledge of the
instrument spectral and spatial response functions. Partial compliance was
established for the straylight correction; especially the
out-of-spectral-band correction for the near-infrared channel needs future validation.
The absolute radiometric calibration of the radiance and irradiance
responsivity is compliant with the high-level mission requirements, but not
with the stricter calibration requirements as the available on-ground
validation shows. The relative radiometric calibration of the Sun port was
non-compliant. The non-compliant subjects will be addressed during the
in-flight commissioning phase in the first 6 months following launch.
Nitrogen dioxide (NO2) is one of the main data products measured by the Tropospheric Monitoring Instrument (TROPOMI) on the Sentinel-5 Precursor (S5P) satellite, which combines a high signal-to-noise ...ratio with daily global coverage and high spatial resolution. TROPOMI provides a valuable source of information to monitor emissions from local sources such as power plants, industry, cities, traffic and ships, and variability of these sources in time. Validation exercises of NO2 v1.2–v1.3 data, however, have revealed that TROPOMI's tropospheric vertical column densities (VCDs) are too low by up to 50 % over highly polluted areas. These findings are mainly attributed to biases in the cloud pressure retrieval, the surface albedo climatology and the low resolution of the a priori profiles derived from global simulations of the TM5-MP chemistry model.This study describes improvements in the TROPOMI NO2 retrieval leading to version v2.2, operational since 1 July 2021. Compared to v1.x, the main changes are the following. (1) The NO2-v2.2 data are based on version-2 level-1b (ir)radiance spectra with improved calibration, which results in a small and fairly homogeneous increase in the NO2 slant columns of 3 % to 4 %, most of which ends up as a small increase in the stratospheric columns. (2) The cloud pressures are derived with a new version of the FRESCO cloud retrieval already introduced in NO2-v1.4, which led to a lowering of the cloud pressure, resulting in larger tropospheric NO2 columns over polluted scenes with a small but non-zero cloud coverage. (3) For cloud-free scenes a surface albedo correction is introduced based on the observed reflectance, which also leads to a general increase in the tropospheric NO2 columns over polluted scenes of order 15 %. (4) An outlier removal was implemented in the spectral fit, which increases the number of good-quality retrievals over the South Atlantic Anomaly region and over bright clouds where saturation may occur. (5) Snow/ice information is now obtained from ECMWF weather data, increasing the number of valid retrievals at high latitudes.On average the NO2-v2.2 data have tropospheric VCDs that are between 10 % and 40 % larger than the v1.x data, depending on the level of pollution and season; the largest impact is found at mid and high latitudes in wintertime. This has brought these tropospheric NO2 closer to Ozone Monitoring Instrument (OMI) observations. Ground-based validation shows on average an improvement of the negative bias of the stratospheric (from -6 % to -3 %), tropospheric (from -32 % to -23 %) and total (from -12 % to -5 %) columns. For individual measurement stations, however, the picture is more complex, in particular for the tropospheric and total columns.
Nitrogen dioxide (NO.sub.2) is one of the main data products measured by the Tropospheric Monitoring Instrument (TROPOMI) on the Sentinel-5 Precursor (S5P) satellite, which combines a high ...signal-to-noise ratio with daily global coverage and high spatial resolution. TROPOMI provides a valuable source of information to monitor emissions from local sources such as power plants, industry, cities, traffic and ships, and variability of these sources in time. Validation exercises of NO.sub.2 v1.2-v1.3 data, however, have revealed that TROPOMI's tropospheric vertical column densities (VCDs) are too low by up to 50 % over highly polluted areas. These findings are mainly attributed to biases in the cloud pressure retrieval, the surface albedo climatology and the low resolution of the a priori profiles derived from global simulations of the TM5-MP chemistry model.
Nitrogen dioxide (NO2) is one of the main data products measured by the Tropospheric Monitoring Instrument (TROPOMI) on the Sentinel-5 Precursor (S5P) satellite, which combines a high signal-to-noise ...ratio with daily global coverage and high spatial resolution. TROPOMI provides a valuable source of information to monitor emissions from local sources such as power plants, industry, cities, traffic and ships, and variability of these sources in time. Validation exercises of NO2 v1.2–v1.3 data, however, have revealed that TROPOMI's tropospheric vertical column densities (VCDs) are too low by up to 50 % over highly polluted areas. These findings are mainly attributed to biases in the cloud pressure retrieval, the surface albedo climatology and the low resolution of the a priori profiles derived from global simulations of the TM5-MP chemistry model. This study describes improvements in the TROPOMI NO2 retrieval leading to version v2.2, operational since 1 July 2021. Compared to v1.x, the main changes are the following. (1) The NO2-v2.2 data are based on version-2 level-1b (ir)radiance spectra with improved calibration, which results in a small and fairly homogeneous increase in the NO2 slant columns of 3 % to 4 %, most of which ends up as a small increase in the stratospheric columns. (2) The cloud pressures are derived with a new version of the FRESCO cloud retrieval already introduced in NO2-v1.4, which led to a lowering of the cloud pressure, resulting in larger tropospheric NO2 columns over polluted scenes with a small but non-zero cloud coverage. (3) For cloud-free scenes a surface albedo correction is introduced based on the observed reflectance, which also leads to a general increase in the tropospheric NO2 columns over polluted scenes of order 15 %. (4) An outlier removal was implemented in the spectral fit, which increases the number of good-quality retrievals over the South Atlantic Anomaly region and over bright clouds where saturation may occur. (5) Snow/ice information is now obtained from ECMWF weather data, increasing the number of valid retrievals at high latitudes. On average the NO2-v2.2 data have tropospheric VCDs that are between 10 % and 40 % larger than the v1.x data, depending on the level of pollution and season; the largest impact is found at mid and high latitudes in wintertime. This has brought these tropospheric NO2 closer to Ozone Monitoring Instrument (OMI) observations. Ground-based validation shows on average an improvement of the negative bias of the stratospheric (from −6 % to −3 %), tropospheric (from −32 % to −23 %) and total (from −12 % to −5 %) columns. For individual measurement stations, however, the picture is more complex, in particular for the tropospheric and total columns.
The Ozone Monitoring Instrument (OMI) was launched on 15 July 2004, with an expected mission lifetime of 5 years. After more than 17 years in orbit the instrument is still functioning satisfactorily ...and in principle can continue doing so until the expected decommissioning of its platform Aura in 2025. In order to continue the datasets acquired by OMI and the Microwave Limb Sounder, the mission was extended up to at least 2023.
Actions have been taken to ensure the proper functioning of the OMI operations, the data processing, and the calibration monitoring system until the eventual end of the mission. For the data processing a new level-0 (L0) to level-1b (L1b) data processor was built based on the recent developments for the TROPOspheric Monitoring Instrument (TROPOMI). With corrections for the degradation of the instrument now included, it is feasible to generate a new data collection to
supersede the current collection-3 data products and reprocess the data of the entire mission up to now.
This paper describes the differences between the collection-3 and collection-4 data. It will be shown that the collection-4 L1b data comprise a clear improvement with respect to the previous collections. By correcting for the gentle optical and electronic aging that has occurred over the past 17 years, OMI’s ability to make trend-quality ozone measurements has further improved.
The immunological barrier currently precludes the clinical utilization of allogeneic stem cells. Although glial-restricted progenitors have become attractive candidates to treat a wide variety of ...neurological diseases, their survival in immunocompetent recipients is limited. In this study, we adopted a short-term, systemically applicable co-stimulation blockade-based strategy using CTLA4-Ig and anti-CD154 antibodies to modulate T-cell activation in the context of allogeneic glial-restricted progenitor transplantation. We found that co-stimulation blockade successfully prevented rejection of allogeneic glial-restricted progenitors from immunocompetent mouse brains. The long-term engrafted glial-restricted progenitors myelinated dysmyelinated adult mouse brains within one month. Furthermore, we identified a set of plasma miRNAs whose levels specifically correlated to the dynamic changes of immunoreactivity and as such could serve as biomarkers for graft rejection or tolerance. We put forward a successful strategy to induce alloantigen-specific hyporesponsiveness towards stem cells in the CNS, which will foster effective therapeutic application of allogeneic stem cells.
In Zeiten einer global fortschreitenden Urbanisierung der Lebenswelten gewinnen Imaginationen und Projektionen eines guten Lebens auf dem Land eine neue diskursive Attraktivität. Sie verweisen auf ...eine lange und ambivalente Geschichte zwischen Anforderungen und Überforderungen gesellschaftlichen Wandels sowie den Ansprüchen auf ein gelingendes Leben. Angesichts umfassender Transformationen, Krisen und Katastrophen bieten die kulturellen Produktionen ländlicher Lebensverhältnisse - und damit verbunden die Vorstellungen von Natur, Idylle und Heimat - sowohl idealisierte Sehnsuchtsorte als auch konkretisierte Orientierungspunkte. Land und Ländlichkeit geraten in ein komplexes Spannungsverhältnis, das auch Auskunft gibt über Wahrnehmung und Selbstverständnis im Leben in und zwischen Stadt und Land.
Esthesioneuroblastoma is a rare malignant intranasal tumor that originates from the olfactory neuroepithelium of the upper nasal cavity, and can destroy the cribriform plate and expand into the ...neurocranium. Descriptions of the magnetic resonance features of esthesioneuroblastomas in animals are scarce. The objectives of this study were to report the magnetic resonance imaging features of esthesioneuroblastomas in order to determine distinct imaging characteristics that may help distinguish it from other intracranial tumor types.
Magnetic resonance images of four patients with confirmed esthesioneuroblastomas were reviewed and compared with previously reported cases.
The esthesioneuroblastomas appeared as oval-shaped, solitary lesions in the caudal nasal cavity that caused osteolysis of the cribriform plate and extended into the brain in all cases. Signal intensity was variable. Contrast enhancement was mild and varied from homogeneous to heterogeneous. A peripheral cystic component was found in two patients and was reported in only one previous case. Mass effect and white matter edema were marked to severe. Osteolysis of facial bones and extension into the facial soft tissues or retrobulbar space were not present in any of the cases, although this has been reported in the literature.
A definitive diagnosis of esthesioneuroblastoma based on signal intensity or contrast behavior was not possible. Nevertheless, the presence of a mass in the caudal nasal cavity with extension into the neurocranium seems to be a feature highly suspicious of esthesioneuroblastoma. In contrast to other extra-cranial lesions, the extra-cranial mass was relatively small and destruction of facial bones seems to be rare.