Specific absorption rate (SAR) patterns for an insulated sleeve dipole applicator, operating at 433 MHz, were measured by infrared thermography. The applicator was modeled using classical ...transmission-line theory, and experimental and theoretical results were compared. In general, agreement between measured and calculated SAR values was good. However, at the antenna feedpoint, the measured values were appreciably higher than the calculated values. This indicates that inclusion of junction effects would improve the model.< >
A phased-array 915-MHz microwave system consisting of four 13x13 cm square applicators was constructed and tested for its design in heating both deep and superficial tumors in cylindrical structures ...such as the upper and lower extremities or neck. Since each applicator produced SAR patterns in cylindrical phantoms in a plane through the array similar to those produced by a plane wave, a theoretical analysis of the SAR patterns due to the superposition of four plane waves incident on a cyIindrical tissue was done. By altering the orientation of the E-field (either parallel or perpendicular to the axis of the cylinder), as well as the phase and amplitude of the incident waves, various distinct SAR patterns were predicted. Thermograms used to experimentally verify the SAR patterns produced by the four applicators showed similar results with those predicted by the plane-wave analysis. A patient with recurrent melanomas on a lower leg was subjected to a clinical trial of hyperthermia in which high tissue temperatures were produced by utilizing two sets of the phased-array system in series. A therapeutic temperature of 43°C in tumor tissues was confirmed by invasive thermometry with high-resistance thermistors.
Polyarteritis nodosa is a systemic necrotising vasculitis that affects the small- and medium-sized arteries. Multifocal aneurysmal formation in the renal, hepatic, and mesenteric vasculature is a ...hallmark of this condition, and spontaneous aneurysmal rupture may occur, resulting in life-threatening haemorrhage. We describe a 42-year-old man who initially presented with fever of unknown origin. A diagnosis could not be reached at that time despite extensive investigations. The fever subsided spontaneously after 8 weeks, and the patient remained well for 6 years until he was admitted again for evaluation of fever. During his hospital stay, he developed a spontaneous massive intra-hepatic haemorrhage resulting in hepatic rupture and a haemoperitoneum. The bleeding was controlled at emergency laparotomy. An abdominal angiography demonstrated multiple microaneurysms in the hepatic and mesenteric arterial vasculature. The clinical findings suggested polyarteritis nodosa, and the source of bleeding was probably a ruptured intra-hepatic artery aneurysm.
The specific absorption rate (SAR) patterns of two 434-MHz hyperthermia applicators, models TCA 434-1 (9 X 20 cm) and TCA 434-2 (13 X 25 cm), were evaluated thermographically using a phantom model. ...The phantom model consisted of a 2-cm-thick layer of fat and a 10-cm depth of muscle contained in a 30 X 30 cm base Plexiglas box. The model was bisected in the middle. Polyester screens at the interface allowed the synthetic gel to make electrical contact between the two halves of the muscle tissue. Octyl alcohol was applied to the fat interface to ensure continuity of dielectric properties. Thermograms were taken for both applicators over the following areas of the exposed model: (1) fat surface, (2) internal surface with E-field parallel to interface, and (3) internal surface with E-field perpendicular to interface. SAR's were calculated from the temperature rise (8 degrees C maximum), net input power (550-650 W), exposure time (15-60 s), and specific heat of the muscle (0.86 kcal/kg degrees C). A factor of 0.42 needs to be multiplied to correct for the specific heat of fat. High localized SAR's along the broad sides of the applicators were seen when the applicators were in direct contact with the phantom. With the use of a 0.8-cm polystyrene foam spacing, the SAR's within the aperture of the applicators were relatively uniform. The patterns of the two applicators were quite similar. However, the TCA 434-1 applicator is smaller and more applicable for clinical conditions.
The purposes of this study were to: (1) investigate the correlation between the color difference of bilayer porcelain veneers over white and black backgrounds (deltaE1) and their opacity (contrast ...ratios); (2) determine whether there is a recommendable threshold contrast ratio above which the color difference is clinically acceptable (when deltaE < or = 5); and (3) compare the ability of porcelain veneers to mask a color change from white to black backgrounds (deltaE1) and their ability to mask a color change from white to clinically discolored teeth (deltaE2).
Forty-four maxillary anterior teeth of eight patients with severe tetracycline discoloration were prepared for bilayer porcelain veneers in shade A2 porcelain. The cores were 0.25 mm thick. The color (CIE L*a*b*) and reflectance (Y) of the midbuccal region of each veneer were measured over white and black backgrounds using a colorimeter under artificial daylight. The veneers were bonded to discolored teeth, and their color was measured after 1 week.
The mean color difference deltaE1 was 10.6 (SD 2.6). The mean contrast ratio was 0.75 (SD 0.1). There was a close and statistically significant correlation between deltaE1 and contrast ratio. The determined threshold contrast ratio was 0.91. The mean color difference deltaE2 was 11.6 (SD 5.5). A paired t test showed no difference between deltaE1 and deltaE2.
There was a significant correlation between the masking ability of veneers (deltaE1) and their opacity (contrast ratio). There was no significant difference in the ability of the porcelain veneers in masking a color change from white to black backgrounds compared to their ability to mask the color change from white to the discolored teeth.
Rectal mucosal ornithine decarboxylase (ODC) activity has been reported to distinguish between patients with and without adenomatous polyps (AP). In the present investigation, ODC activity has been ...measured in 28 patients with AP and 34 patients without AP. To assess the intraindividual variation in ODC activity, repeat biopsies were performed on 11 patients. In addition, the effect of postbiopsy sample handling was investigated by storage of samples on either dry or wet ice during transport to the laboratory. The mean rectal mucosal ODC activity in patients with AP was 196.0 +/- 195.5, whereas that in AP negative patients was 182.2 +/- 320.5. The rectal mucosal ODC activity in patients with colorectal cancer was 388.2 +/- 581. Repeat samples in individuals were generally within the same range as the original samples. The method of sample transport did not significantly affect the level of ODC measured in a particular biopsy. Because of high variability in rectal mucosal ODC activity within the population, there was wide overlap in ODC values between those patients with and without AP in an unselected general population. Thus, the measurement of flat rectal mucosal ODC activity is not a good predictor of the presence or absence of AP. Additional studies of the factors affecting mucosal ODC activity are necessary before the potential clinical utility of the method can be realized in the general population.
