Sexual violence against young girls is a pervasive multifaceted phenomenon which embraces several different forced sexual acts, including attempted and/or completed rape, sexual coercion and ...harassment, and sexual contact with force or threat of force. The aim of this study is to evaluate the characteristics of sexual violence in adolescent girls, by a retrospective analysis of 731 consecutive cases of sexually abused girls.
We analyzed demographic characteristics, risk factors for rape, and the eventual subsequent presence and type of ano-genital lesions.
We found that sexual violence with penetration was perpetrated in 591 (80%) cases. Vulnerability factors related with a major risk of rape were age >17 years old and consumption of alcohol and/or other drugs. About 196 (55%) victims had at a least one genital lesion.
A prompt identification of red flags of sexual violence may help physicians in suspecting and managing cases of sexual assault in adolescent girls, even in the absence of typical lesions.
C1 inhibitor deficiency is a rare, potentially lethal condition that can be either inherited (hereditary angioedema, HAE) or acquired (acquired angioedema, AAE). Substitutive therapy with C1-INH ...concentrate is the treatment of choice for severe acute attacks of angioedema in Europe.
We report the need and effect of C1-INH concentrate in 448 patients with HAE and 25 with AAE. Time to beginning of resolution of attacks, side effects were recorded.
We recorded 326 infusions of C1 inhibitor plasma concentrate in 127 HAE patients (mean infusion/patient 2.5, range 1-17) and 89 infusion in 8 AAE patients (mean infusion/patient 11.1, range 1-27). Dose of concentrate ranged from 500U to 2000U for HAE, 1000U-12000U for AAE. Time to beginning of resolution was 1 hour in 303 (93%), between 1 and 2 hours in 7 and between 2 and 12 hours in the remaining 16 patients. One HAE patient underwent tracheostomy for laryngeal edema despite treatment with C1-INH concentrate. In 5 patients with AAE (54 infusions) beginning of resolution was always within one hour; in the remaining 3 patients (35 infusions) the response became progressively slow 3 (3 hours or more) requiring higher doses of C1-INH concentrate. One anaphylactic reaction and 2 generalized cutaneous reactions were reported in 2 patients with HAE. Transmission of HCV has been recorded before introduction of virucidal methods.
C1 inhibitor concentrate is effective and safe for treatment of severe symptoms in the majority of patients with HAE. Patients with AAE may become resistant to the treatment.
Part I of the report covers the discussion and recommendations of the meeting while communications and papers are given in part II. Briefings on IPGRI and ECP/GR, report of the Working Group Chair, ...status of the European Malus and Pyrus databases, overview of the EPGRIS project, status of national collections, phytosanitory and legal aspects of apple and pear germplasm exchange in Europe, definition of a system for international responsibility for the conservation of apple and pear germplasm in Europe; and Collection, evaluation and use of wild species of Malus and Pyrus are presented. Research activities concerning molecular identification of fruit genetic resources, durable apple resistance evaluation, Belgian network for Malus and Pyrus genetic resources, the ISHS (International Society for Horticultural Science) Pear working group and SERIDA (Servicio Regionoal de Investigación y Desarrollo Agroalimentario del Principado de Asturias) are reviewed. Country reports on national collections and research were presented. Evaluation descriptors for Malus, Model for a Memorandum of responsibility, Establishment of a European Malus/Pyrus Collection and a report of an extraordinary meeting of the ECP/GR Working Group on Malus/Pyrus held during the EUCARPIA Symposium, 2 September 2003, are included
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