We explain the principles of gene expression pattern stabilization in systems of interacting, diffusible morphogens, with dynamically established source regions. Using a reaction-diffusion model with ...a step-function production term, we identify the phase transition between low-precision indeterminate patterning and the phase in which a traveling, well-defined contact zone between two domains is formed. Our model analytically explains single- and two-gene domain dynamics and provides pattern stability conditions for all possible two-gene regulatory network motifs.
Clustering in low density nuclear matter has been investigated using the NIMROD multidetector at Texas A&M University. Thermal coalescence modes were employed to extract densities, ρ, and ...temperatures, T, for evolving systems formed in collisions of 47A MeV (40)Ar+(112)Sn, (124)Sn and (64)Zn+(112)Sn, (124)Sn. The yields of d, t, (3)He, and (4)He have been determined at ρ=0.002 to 0.03 nucleons/fm(3) and T=5 to 11 MeV. The experimentally derived equilibrium constants for α particle production are compared with those predicted by a number of astrophysical equations of state. The data provide important new constraints on the model calculations.
Least-cost models for focal species are widely used to design wildlife corridors. To evaluate the least-cost modeling approach used to develop 15 linkage designs in southern California, USA, we ...assessed robustness of the largest and least constrained linkage. Species experts parameterized models for eight species with weights for four habitat factors (land cover, topographic position, elevation, road density) and resistance values for each class within a factor (e.g., each class of land cover). Each model produced a proposed corridor for that species. We examined the extent to which uncertainty in factor weights and class resistance values affected two key conservation-relevant outputs, namely, the location and modeled resistance to movement of each proposed corridor. To do so, we compared the proposed corridor to 13 alternative corridors created with parameter sets that spanned the plausible ranges of biological uncertainty in these parameters. Models for five species were highly robust (mean overlap 88%, little or no increase in resistance). Although the proposed corridors for the other three focal species overlapped as little as 0% (mean 58%) of the alternative corridors, resistance in the proposed corridors for these three species was rarely higher than resistance in the alternative corridors (mean difference was 0.025 on a scale of 1–10; worst difference was 0.39). As long as the model had the correct rank order of resistance values and factor weights, our results suggest that the predicted corridor is robust to uncertainty. The three carnivore focal species, alone or in combination, were not effective umbrellas for the other focal species. The carnivore corridors failed to overlap the predicted corridors of most other focal species and provided relatively high resistance for the other focal species (mean increase of 2.7 resistance units). Least-cost modelers should conduct uncertainty analysis so that decision-makers can appreciate the potential impact of model uncertainty on conservation decisions. Our approach to uncertainty analysis (which can be called a worst-case scenario approach) is appropriate for complex models in which distribution of the input parameters cannot be specified.
In-medium binding energies and Mott points for d, t, 3He and α clusters in low-density nuclear matter have been determined at specific combinations of temperature and density in low-density nuclear ...matter produced in collisions of 47A MeV 40Ar and 64Zn projectiles with 112Sn and 124Sn target nuclei. The experimentally derived values of the in-medium modified binding energies are in good agreement with recent theoretical predictions based upon the implementation of Pauli blocking effects in a quantum statistical approach.
Midrapidity production of π±, K±, and (¯p)p measured by the ALICE experiment at the CERN Large Hadron Collider, in Pb-Pb and inelastic pp collisions at √sNN=5.02 TeV, is presented. The invariant ...yields are measured over a wide transverse momentum (pT) range from hundreds of MeV/c up to 20 GeV/c. The results in Pb-Pb collisions are presented as a function of the collision centrality, in the range 0–90%. The comparison of the pT-integrated particle ratios, i.e., proton-to-pion (p/π) and kaon-to-pion (K/π) ratios, with similar measurements in Pb-Pb collisions at √sNN=2.76 TeV show no significant energy dependence. Blast-wave fits of the pT spectra indicate that in the most central collisions radial flow is slightly larger at 5.02 TeV with respect to 2.76 TeV. Particle ratios (p/π, K/π) as a function of pT show pronounced maxima at pT≈3GeV/c in central Pb-Pb collisions. At high pT, particle ratios at 5.02 TeV are similar to those measured in pp collisions at the same energy and in Pb-Pb collisions at √sNN=2.76 TeV. Using the pp reference spectra measured at the same collision energy of 5.02 TeV, the nuclear modification factors for the different particle species are derived. Within uncertainties, the nuclear modification factor is particle species independent for high pT and compatible with measurements at √sNN=2.76 TeV. The results are compared to state-of-the-art model calculations, which are found to describe the observed trends satisfactorily.
The first evidence of spin alignment of vector mesons ( K*0 and ϕ ) in heavy-ion collisions at the Large Hadron Collider (LHC) is reported. The spin density matrix element ρ 00 is measured at ...midrapidity ( | y | < 0.5 ) in Pb-Pb collisions at a center-of-mass energy ( √sNN ) of 2.76 TeV with the ALICE detector. ρ 00 values are found to be less than 1/3 (1/3 implies no spin alignment) at low transverse momentum ( p T < 2 GeV / c ) for K*0 and ϕ at a level of 3 σ and 2 σ , respectively. No significant spin alignment is observed for the K0S meson ( spin = 0 ) in Pb-Pb collisions and for the vector mesons in p p collisions. The measured spin alignment is unexpectedly large but qualitatively consistent with the expectation from models which attribute it to a polarization of quarks in the presence of angular momentum in heavy-ion collisions and a subsequent hadronization by the process of recombination.
One of the key challenges for nuclear physics today is to understand from first principles the effective interaction between hadrons with different quark content. First successes have been achieved ...using techniques that solve the dynamics of quarks and gluons on discrete space-time lattices
. Experimentally, the dynamics of the strong interaction have been studied by scattering hadrons off each other. Such scattering experiments are difficult or impossible for unstable hadrons
and so high-quality measurements exist only for hadrons containing up and down quarks
. Here we demonstrate that measuring correlations in the momentum space between hadron pairs
produced in ultrarelativistic proton-proton collisions at the CERN Large Hadron Collider (LHC) provides a precise method with which to obtain the missing information on the interaction dynamics between any pair of unstable hadrons. Specifically, we discuss the case of the interaction of baryons containing strange quarks (hyperons). We demonstrate how, using precision measurements of proton-omega baryon correlations, the effect of the strong interaction for this hadron-hadron pair can be studied with precision similar to, and compared with, predictions from lattice calculations
. The large number of hyperons identified in proton-proton collisions at the LHC, together with accurate modelling
of the small (approximately one femtometre) inter-particle distance and exact predictions for the correlation functions, enables a detailed determination of the short-range part of the nucleon-hyperon interaction.
Comprehensive results on the production of unidentified charged particles, π±, K±, K$_S^0$, K*(892)0, $p, \bar{p}, ϕ$(1020), Λ, Λ, Ξ-, Ξ+, Ω-, and $\bar{Ω}^+$ hadrons in proton-proton ...(pp) collisions at $ \sqrt{s}$=7 TeV at midrapidity (|y|<0.5) as a function of charged-particle multiplicity density are presented. In order to avoid autocorrelation biases, the actual transverse momentum (pT) spectra of the particles under study and the event activity are measured in different rapidity windows. In the highest multiplicity class, the charged-particle density reaches about 3.5 times the value measured in inelastic collisions. While the yield of protons normalized to pions remains approximately constant as a function of multiplicity, the corresponding ratios of strange hadrons to pions show a significant enhancement that increases with increasing strangeness content. Furthermore, all identified particle-to-pion ratios are shown to depend solely on charged-particle multiplicity density, regardless of system type and collision energy. The evolution of the spectral shapes with multiplicity and hadron mass shows patterns that are similar to those observed in p-Pb and Pb-Pb collisions at Large Hadron Collider energies. The obtained pT distributions and yields are compared to expectations from QCD-based pp event generators as well as to predictions from thermal and hydrodynamic models. These comparisons indicate that traces of a collective, equilibrated system are already present in high-multiplicity pp collisions.
This article reports measurements of the pT-differential inclusive jet cross section in pp collisions at s=5.02TeV and the pT-differential inclusive jet yield in Pb-Pb 0-10% central collisions at ...sNN=5.02TeV. Jets were reconstructed at midrapidity with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm. For pp collisions, we report jet cross sections for jet resolution parameters R=0.1-0.6 over the range 20<pT,jet<140 GeV/c, as well as the jet cross-section ratios of different R and comparisons to two next-to-leading-order (NLO)-based theoretical predictions. For Pb-Pb collisions, we report the R=0.2 and R=0.4 jet spectra for 40<pT,jet<140 GeV/c and 60<pT,jet<140 GeV/c, respectively. The scaled ratio of jet yields observed in Pb-Pb to pp collisions, RAA, is constructed, and exhibits strong jet quenching and a clear pT dependence for R=0.2. No significant R dependence of the jet RAA is observed within the uncertainties of the measurement. These results are compared to several theoretical predictions.
The pseudorapidity density of charged particles, dNch / d η , at midrapidity in Pb-Pb collisions has been measured at a center-of-mass energy per nucleon pair of √ s N N = 5.02 TeV . For the 5% ...most central collisions, we measure a value of 1943 ± 54 . The rise in dNch / d η as a function of √ s N N is steeper than that observed in proton-proton collisions and follows the trend established by measurements at lower energy. The increase of dNch / d η as a function of the average number of participant nucleons, ⟨ N part ⟩ , calculated in a Glauber model, is compared with the previous measurement at √ s N N = 2.76 TeV . A constant factor of about 1.2 describes the increase in dNch / d η from √ s N N = 2.76 to 5.02 TeV for all centrality classes, within the measured range of 0%–80% centrality. The results are also compared to models based on different mechanisms for particle production in nuclear collisions.
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