New precise results of a measurement of the elastic electron-proton scattering cross section performed at the Mainz Microtron MAMI are presented. About 1400 cross sections were measured with negative ...four-momentum transfers squared up to Q² = 1 (GeV/c)² with statistical errors below 0.2%. The electric and magnetic form factors of the proton were extracted by fits of a large variety of form factor models directly to the cross sections. The form factors show some features at the scale of the pion cloud. The charge and magnetic radii are determined to be <r²E>½ = 0.879(5)stat(4)syst(2)model(4)group fm and <r²M>½ = 0.777(13)stat(9)syst(5)model(2)group fm.
The zoonotic potential of Mycobacterium tuberculosis complex species is well known. However, M. pinnipedii, the causative agent of tuberculosis (TB) predominantly in seals and sea lions, has never ...been isolated from a respiratory specimen in humans. Here we describe the
first known human case of pulmonary TB caused by M. pinnipedii in a 79-year-old female patient with rheumatoid arthritis and chronic respiratory disease. The epidemiological data did not explain where the patient was exposed to M. pinnipedii, thus leaving the source of transmission
unknown.
Literature Highlights Makek, M. Jankovic; Amorim, G. G. C.; Ragonnet, R. ...
The international journal of tuberculosis and lung disease,
08/2023, Letnik:
27, Številka:
8
Journal Article
Recenzirano
Literature Highlights is a digest of notable papers recently published in the leading respiratory journals. Coverage includes shorter regimen for TB treatment; mapping the geographical evolution of ...TB incidence; diagnostic packages for active case finding for TB; TB burden estimation
in settings with high levels of HIV; and digital approaches for TB treatment adherence.
Literature Highlights Makek, M. J.; Tiberi, S.; Felker, I. ...
The international journal of tuberculosis and lung disease,
06/2023, Letnik:
27, Številka:
6
Journal Article
Recenzirano
Literature Highlights is a digest of notable papers recently published in the leading respiratory journals. Coverage includes clinical trials to investigate the diagnostic and clinical effect of ...trial of antibiotics on TB; a Phase 3 trial to assess if glucocorticoids decrease mortality
among patients with pneumonia; a Phase 2 trial on pretomanid use for treating drug-susceptible TB; contact investigation for TB in China; and post-TB sequelae after TB treatment in children.
Abstract
We measured azimuthal correlations of the Compton-scattered gamma quanta from positron annihilation with two 8 × 8 matrices of Gadolinium Aluminum Gallium Garnet doped with Cerium. Each ...detector matrix contains 64 crystals of size 3 mm × 3 mm × 20 mm and it is read-out by a single Silicon Photo-multiplier (SiPM) array, with one SiPM matching one pixel. The studied single-side readout concept keeps the modules compact and cost-efficient on a large scale. Coincidence events were recorded using a Na-22 source placed between the modules. We clearly identify and reconstruct the Compton scattering events and we observe the excess of orthogonally scattered gammas over the ones with the parallel azimuthal angles. We present the measured azimuthal modulation factors for several kinematic selection criteria and different inter-pixel distances.
Chylous effusion is a rare manifestation of systemic lupus erythematosus (SLE). When it does occur in SLE, it is generally well treated with standard pharmacologic or surgical measures. We present a ...decade of management in a case of SLE with lung affliction and development of refractory bilateral chylous effusion and pulmonary arterial hypertension (PAH). In the first years, the patient was treated under a Sjogren syndrome diagnose. After few years, her respiratory condition worsened due to chylous effusion and PAH. Immunosuppression therapy (methylprednisolone) was reintroduced, and vasodilator therapy commenced. With this, her cardiac function remained stable, but respiratory function continuously worsened despite several therapy trials with different combinations of immunosuppressant (glucocorticoids, resochin, cyclophosphamide and mycophenolate mofetil). On top of pleural effusion worsening, the patient developed ascites and severe hypoalbuminaemia. Even though albumin loss was stabilized with monthly octreotide applications, the patient remained respiratory insufficient and in need of continuous oxygen therapy. At that point, we decided to introduce sirolimus on top of glucocorticoids and mycophenolate mofetil therapy. Her clinical status, radiological finding, and lung function gradually improved and she became respiratory sufficient at rest. The patient remains in our follow-up and has been stable on given therapy for over 3 years despite overcoming a severe COVID-19 pneumonia in 2021. This case adds to the body of evidence of sirolimus effectiveness in patients with refractory systemic lupus and is, to our best knowledge, the first case to report its successful application in a patient with SLE and refractory chylous effusion.
A Hadron Blind Detector (HBD) has been developed, constructed and successfully operated within the PHENIX detector at RHIC. The HBD is a Cherenkov detector operated with pure
CF
4
. It has a 50
cm ...long radiator directly coupled in a windowless configuration to a readout element consisting of a triple GEM stack, with a CsI photocathode evaporated on the top surface of the top GEM and pad readout at the bottom of the stack. This paper gives a comprehensive account of the construction, operation and in-beam performance of the detector.
A highly segmented neutron polarimeter for A1 Spreckels, R.; Hoek, M.; Müller, U. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
05/2024, Letnik:
1062
Journal Article
Recenzirano
Odprti dostop
A new neutron polarimeter for measuring the neutron’s electric form factor was designed and constructed to complement the A1 spectrometer setup at the Mainz Microtron (MAMI). The design is based on a ...previous polarimeter with significant improvements to halve the error of the extracted form factor. A higher granularity of the polarimeter sections and a deeper first section on the one hand, and a faster readout employing Time-over-Threshold methods to measure the signal amplitudes combined with a high-precision FPGA-based TDC on the other hand will allow to achieve this goal. The performance of the new polarimeter during a first measurement campaign in 2019 using liquid hydrogen and deuterium targets will be discussed.
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