Relationships between degree/area of academic formation and religious and Darwinian views are controversial. This study aimed to compare the religious beliefs and acceptance of Darwinian evolution ...between two contrasting South American scientific communities (Chile and Colombia), accounting for different degrees and areas of academic formation. In 2018, 115 last year bachelor students (surveyed as freshmen in 2014 for a previous study) from Chile, and 283 first/last year bachelor students, graduate students, and professors from Colombia, all belonging to biology, chemistry, or physics, were surveyed. Chilean students/faculty were significantly more agnostic/atheist, more accepting of Darwinian evolution, and less creationist than their Colombian counterparts. Academic degree and area differently affected these views in both countries, as only in Chile there was a clear tendency among biologists and physicists with higher degrees to hold less religious and creationist views. Marked differences between the history, socioeconomic contexts, and especially in high school and university curricula of both countries might explain these results.
Rockall score is the most widely used prognostic scale for assessing risk of complications from non-varicose upper gastrointestinal bleeding (UGIB). Several studies have been conducted in adult ...populations with non-varicose UGIB in different parts of the world, with conflicting findings regarding the extent of association between the score and some morbidity and mortality outcomes. Also, there is controversy regarding the best cut-off point for the score. Moreover, no studies validating this score in Colombia have been carried out.
To assess the diagnostic performance of the Rockall score in predicting rebleeding and mortality in patients with non-varicose UGIB.
A prospective cohort study was conducted in patients requiring upper gastrointestinal endoscopy (UGIE) for non-varicose bleeding. The pre-and post-endoscopy Rockall scores were calculated and outcomes, including mortality, UGIB-associated mortality and in hospital rebleeding were determined at the 1 and 3-month time points. The association between the scores and these outcomes was assessed using the chi2 or the Fisher test, whereas the discrimination ability of the score was determined using the areas under the ROC curve (AUC). High discrimination ability was considered to exist in cases in which an AUC ≤0.7 with α=0.05 could be rejected.
Overall, 177 patients were analyzed. In-hospital outcomes at 1 and 3 months were 12%, 17% and 23% for general mortality, 6%, 12% and 15% for UGIB mortality, and 19%, 30% and 37% for rebleeding. The post-endoscopy Rockall score was associated with the three outcomes at the three time points assessed, while the pre-endoscopy score was only associated with general mortality at the three time points, and rebleeding at 1 and 3 months. Regarding discrimination ability, although the AUC was greater than expected by randomness (0.5) in all cases, only one AUC ≤0.7 was rejected in the post-endoscopy score for in-hospital UGIB mortality (AUC=0.901; 95%CI: 0.845-0.958), at 1 month (AUC=0.836; 95%CI: 0.717-0.954) and at 3 months (AUC=0.869; 95%CI: 0.771-0.967), and for rebleeding at 1 month (AUC=0.793; 95%CI: 0.725-0.861) and at 3 months (AUC=0.806; 95%CI: 0.741-0.871).
An association was found between the Rockall score and rebleeding and mortality in patients with non-varicose UGIB. Only the post-endoscopy score had a high predictive ability for rebleeding and UGIB mortality.
Introduction. Diabetes mellitus (DM) is a highly prevalent disease worldwide. It has been associated with an important morbimortality due to its complications and sometimes as a result of adverse ...events related to treatment. Insulin pump therapy (IPT) is one of the options used to control this disease and reduces one of the most frequent complication associated with treatment: hypoglycemia, which has also a great impact on life quality and clinical status of patients. Materials and Methods. A descriptive and retrospective study was performed including patients treated and followed by the department of endocrinology from a high-complexity university hospital in Cali, Colombia, between 2012 and 2017. Patients were on IPT and continuous glucose monitoring (CGM): MiniMed Paradigm® Veo™ Insulin Pump (Medtronic®) and MiniMed 640G Insulin Pump-Enlite™ Sensor (Medtronic®). Presentation of hypoglycemia and variables associated with its development were evaluated. Results. 51 patients were included. The main indication for IPT initiation was the report of hypoglycemic episodes and inappropriate metabolic control. Initiation of IPT was related with a decrease in glycosylated hemoglobin (HbA1c) and also a decrease in severe hypoglycemic events and hospitalization due to hypoglycemia. The risk factors linked with clinically significant hypoglycemia were male gender, and standard deviation of glucose measures calculated by CGM. A diminished glomerular filtration rate (GFR) (<60 mL/min/1.73 m2) was correlated with higher risk of severe hypoglycemia. Conclusion. IPT with CGM is a useful strategy in the management of patients with DM; it is associated with a reduction of adverse hypoglycemic events and hospitalizations due to hypoglycemia.
Introduction: The platelet count/spleen diameter (PC/SD) ratio is a noninvasive method for the diagnosis of esophageal varices (EV) used as an alternative to endoscopy in patients with cirrhosis.
...Objective: To evaluate the diagnostic performance of the PC/SD ratio (cut-off point <909) to detect EV in patients with cirrhosis treated at a tertiary referral hospital in Bogotá D.C., Colombia.
Materials and methods: A prospective diagnostic test accuracy study was conducted in 66 patients with cirrhosis treated at the Hospital Universitario de La Samaritana between July and December 2018. A descriptive analysis of the data was performed. In addition, the diagnostic performance of the PC/SD ratio (cut-off point <909) for the detection of EV was compared with the findings reported in the esophagogastroduodenoscopy (gold standard), calculating its sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), and negative likelihood ratio (LR-). A significance level of p<0.05 was considered.
Results: The mean age of the participants was 65.5 years, 53.03% were female, and the most common causes of cirrhosis were alcohol consumption (40.90%) and autoimmune hepatitis (22.72%). EV was diagnosed in 48 patients (72.72%). The PC/SC ratio showed sensitivity of 60%, specificity of 78%, PPV of 0.88, NPV of 0.42, LR+ of 2.73, and LR- of 0.51.
Conclusion: The low sensitivity, specificity, and NPV found in the present study suggest that the PC/SD ratio (cut-off point <909) may not be a useful diagnostic test for detecting EV in patients with cirrhosis.
Resumen Introducción: la epidemiología de la disfagia está pobremente definida. Es un síntoma que se asocia con el envejecimiento, y en poblaciones jóvenes sigue siendo tema de incertidumbre. También ...es un problema que no siempre informan los pacientes y es poco comprendido en la población general. Objetivo: describir las características clínicas y epidemiológicas de la disfagia a partir de una muestra de pacientes adultos remitidos a un centro especializado en gastroenterología. Metodología: estudio observacional, descriptivo y retrospectivo, realizado en un centro especializado en gastroenterología en Bogotá D. C. durante 2016, en el cual se revisaron 3148 historias clínicas y se recopilaron aquellas de pacientes cuyo motivo de consulta fuera disfagia o la refirieran como síntoma asociado, y cuyo diagnóstico se confirmara con pruebas complementarias. Resultados: de 3148 historias clínicas, 85 (2,7 %) presentaron disfagia como motivo de consulta principal o síntoma asociado. La mayoría correspondió a mujeres (70,5 %). El grupo de edad más afectado fue entre 70 y 79 años. La enfermedad por reflujo gastroesofágico (ERGE) representó el diagnóstico más frecuente. Conclusión: la prevalencia de disfagia encontrada es similar a la reportada en la literatura. La ERGE es causa frecuente de disfagia. La disfagia continúa siendo un problema predominantemente de adultos mayores.
In vegetables of economic importance such as onion, one of the main limitations in their production is that their seeds have a relatively short storage life, so their viability decreases rapidly. ...Research has been carried out on onions to improve seed germination and to extend its use for sowing. The magnetic field is considered a simple, inexpensive, and non-invasive physical method to stimulate the germination process, compared to traditional chemical methods. In this sense the objective of this research were to evaluate the effects of static magnetic fields on Yellow Granex PRR hybrid onion (Allium cepa L.) seed germination, and early growth in the laboratory conditions. Seeds were exposed to 10 and 21mT, (mT=militesla), static magnetic fields induced by magnets for 0, 5, 3, 6, 12 and 24h; each treatment had four repetitions. The results showed that the low intensity stationary magnetic fields (10 and 21mT) did not cause significant differences in germination, dry weight, or fresh weight, but for the seedling length. It is necessary to increase the intensity of the magnetic fields and the exposure time to achieve important physiological changes that positively affect the germination and growth of onion seeds, and thus contribute to the improvement of their yield and productivity. The use of physical methods such as magnetism can stimulate different physiological processes in plants and thus contribute to the improvement of characteristics of agronomic interest.
In vegetables of economic importance such as onion, one of the main limitations in their production is that their seeds have a relatively short storage life, so their viability decreases rapidly. ...Research has been carried out on onions to improve seed germination and to extend its use for sowing. The magnetic field is considered a simple, inexpensive, and non-invasive physical method to stimulate the germination process, compared to traditional chemical methods. In this sense the objective of this research were to evaluate the effects of static magnetic fields on Yellow Granex PRR hybrid onion (Allium cepa L.) seed germination, and early growth in the laboratory conditions. Seeds were exposed to 10 and 21mT, (mT=militesla), static magnetic fields induced by magnets for 0, 5, 3, 6, 12 and 24h; each treatment had four repetitions. The results showed that the low intensity stationary magnetic fields (10 and 21mT) did not cause significant differences in germination, dry weight, or fresh weight, but for the seedling length. It is necessary to increase the intensity of the magnetic fields and the exposure time to achieve important physiological changes that positively affect the germination and growth of onion seeds, and thus contribute to the improvement of their yield and productivity. The use of physical methods such as magnetism can stimulate different physiological processes in plants and thus contribute to the improvement of characteristics of agronomic interest.
Día a día observamos como las problemáticas sociales inciden en el aula ycomo el aula se adapta de diversas maneras a dichas problemáticas. En losúltimos años una fuerte corriente de educación ...matemática propone la inclusiónde dichas problemáticas al trabajo en el aula. Este documento se proponemostrar una experiencia de aula donde colaborativamente se crearonambientes de aprendizaje que respondieran a las problemáticas de la comunidady se plantea una posible secuencia de actividades para la enseñanza degeometría y espacialidad en quinto grado de educación básica.
El tratamiento de la infección por Helicobacter pylori continúa siendo un problema no resuelto en la práctica clínica con un alto porcentaje de fallas en su erradicación; la principal causa es la ...resistencia antibiótica que varía dependiendo del área geográfica estudiada. Se han desarrollado diversas técnicas para el estudio de la sensibilidad in vitro, pero su utilización en la práctica clínica es difícil de aplicar y costosa. También es importante reconocer que no siempre esta tiene una relación directa con los estudios in vivo pero pueden contribuir a mejorar los resultados de erradicación. En el presente artículo se revisan los mecanismos de resistencia y los artículos publicados en América Latina, sobre resistencia in vitro a los antibióticos más empleados en los esquemas de erradicación. La revisión encontró 35 estudios en Latinoamérica con un total de 3.358 aislados. Las técnicas de sensibilidad empleadas en los estudios de la región fueron E-test 48%, dilución en agar 37% y la difusión en agar 8%. Los estudios presentan bastante heterogeneidad con importantes diferencias entre los países de la región e incluso en estudios realizados en un mismo país. La resistencia in vitro, parametronidazol fue de 65,7%, para amoxicilina de 6,5%, para claritromicina de 14%, para tetraciclina de 8,3%, para levofloxacina de 39% y para furazolidona de 6,9%.
PDF
