We discuss the physics potential and the experimental challenges of an upgraded LHC running at an instantaneous luminosity of 1035 cm-2s-1. The detector R&D needed to operate ATLAS and CMS in a very ...high radiation environment and the expected detector performance are discussed. A few examples of the increased physics potential are given, ranging from precise measurements within the Standard Model (in particular in the Higgs sector) to the discovery reach for several New Physics processes.
This research work presents the investigation of H13 tool steel powder in the production of parts characterized by complex features via selective laser melting. The authors proposed a benchmark ...geometry with 40 mm nominal height, self-supported overhanging structure and internal channels. To investigate powder printability and process capabilities, an experimental campaign was designed as a function of laser power, scan speed and hatching distance. Full dense parts exhibiting 99.92% internal density have been achieved by imposing a laser power equal to 150 W, a scan speed equal to 500 mm/s and a hatching distance equal to 120 µm, while high geometrical accuracy in terms of no material drops along sample edges and low-dimensional deviations of the realized sloping surfaces (i.e., + 0.23° and − 0.90° for nominal 35° and 40° overhang, respectively) has been achieved for 150 W, 1000 mm/s, and 100 µm. Findings open the way to use SLM technology in the design of advanced cutting tool solutions.
Monosomy 1p36 is the most common subtelomeric microdeletion syndrome with an incidence rate estimated to be 1 in 5000 births. A hypothesis of a similarity between patients with 1p36 deletion and ...those with Prader-Willi syndrome and the existence of two different phenotypes for 1p36 microdeletion has been suggested. The main objective of the present study was to determine the existence of 1p36 microdeletion in a sample of patients with mental retardation, obesity and hyperphagia who tested negative by the methylation test for Prader-Willi syndrome. Sixteen patients (7 females, 9 males), 16-26 years old, were evaluated with high-resolution cytogenetic analysis at 550-850 band levels and with 11 polymorphic microsatellite markers located in the 1p36 region. All patients had normal cytogenetic and molecular results. The results obtained by high-resolution cytogenetic methodology were confirmed by the molecular analyses. We did not detect a 1p36 microdeletion in 16 subjects with the Prader-Willi-like phenotype, which reinforces that no correlation seems to exist between Prader-Willi-like phenotype and the 1p36 microdeletion syndrome.
An experience of construction and implementation of nursing care protocols and procedures for district nurses is described. A course was offered to all the district nurses, where the indications for ...the nursing care of some common patients' problems (pressure sores management, mobilization of the stroke patient, the management of patients in pain; the nursing care to stoma patients etc.) were presented. After having compared their work habits with the indications derived from the literature, the nurses were asked to produce protocols and procedures for the problems addressed during the course. The protocols were revised by experts and formally adopted by the responsible of the District, printed in a booklet and mailed with an official letter, to all the district nurses. After two years from the mailing, the knowledge of the nurses (44) on the areas covered by the guidelines was assessed with a multiple choice questionnaire. The level of knowledge varied from 100% of correct answers for the meatal care before catheterization, to the 23% of correct answers on how to remove the needle from a port-a-cath system. The level of knowledge was dishomogenous not only across nurses but also across subjects. In fact low level of correct answers were obtained also for frequently encountered problems, such as patients with pressure sores. The possible causes of the failure of the implementation of the guidelines are discussed.
The barrel muon chambers of the CMS detector consist of three sets of four layers of rectangular drift tubes. The performance of several prototypes was measured in a muon beam for various ...experimental conditions. Special emphasis was given to study performance aspects related to the trigger capability of the chambers.
A citogenética do espermatozóide humano Elza M.P. Sartorelli; Wagner J.M. Paiva; Luiz F. Mazzucato ...
Medicina (Sao Paulo. 197?),
06/1998, Letnik:
32, Številka:
2
Journal Article
Recenzirano
Odprti dostop
A constituição cromossômica do espermatozóide humano pode ser estudada, atualmente, através da técnica de fertilização “in vitro” (FIV), heteróloga, homem/hamster. Essa técnica permite a ...individualização dos cromossomos do espermatozóide humano, possibilitando a análise de suas anomalias numéricas e estruturais. O aprimoramento dessa técnica estimulou um novo campo de pesquisa na Citogenética Humana e na Genética Clínica. Sua implantação em nosso laboratório na Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, propiciará melhor estimativa da probabilidade de transmissão de anomalias cromossômicas por células da linhagem germinativa de homens em risco genético.
A citogenética do espermatozóide humano Sartorelli, Elza M.P.; Paiva, Wagner J.M.; Mazzucato, Luiz F. ...
Medicina (Sao Paulo. 197?),
06/1998, Letnik:
32, Številka:
2
Journal Article
Recenzirano
A constituição cromossômica do espermatozóide humano pode ser estudada, atualmente, através da técnica de fertilização “in vitro” (FIV), heteróloga, homem/hamster. Essa técnica permite a ...individualização dos cromossomos do espermatozóide humano, possibilitando a análise de suas anomalias numéricas e estruturais. O aprimoramento dessa técnica estimulou um novo campo de pesquisa na Citogenética Humana e na Genética Clínica. Sua implantação em nosso laboratório na Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, propiciará melhor estimativa da probabilidade de transmissão de anomalias cromossômicas por células da linhagem germinativa de homens em risco genético.
We report the discovery and analysis of a massive, compact, hierarchical triple system (TIC 470710327) initially identified by citizen scientists in data obtained by NASA’s Transiting Exoplanet ...Survey Satellite (TESS). Spectroscopic follow-up observations obtained with the HERMES spectrograph, combined with eclipse-timing variations (ETVs), confirm that the system is comprised of three OB stars, with a compact 1.10 d eclipsing binary and a non-eclipsing tertiary on a 52.04 d orbit. Dynamical modelling of the system (from radial velocity and ETVs) reveal a rare configuration wherein the tertiary star (O9.5-B0.5V; 14–17 Mꙩ) is more massive than the combined mass of the inner binary (10.9–13.2 Mꙩ). Given the high mass of the tertiary, we predict that this system will undergo multiple phases of mass transfer in the future, and likely end up as a double neutron star gravitational wave progenitor or an exotic Thorne–Żytkow object. Further observational characterization of this system promises constraints on both formation scenarios of massive stars as well as their exotic evolutionary end-products.
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