Summary
Background Environmental, cultural and health care differences may account for variation among countries in the prevalence of asthma and respiratory symptoms in teenagers.
Objective To ...examine the prevalence of respiratory symptoms and the level of diagnosis, and to compare determinants of asthma and severe wheeze in two countries.
Methods Self‐completion questionnaires based on the International Study of Asthma and Allergies in Childhood (ISAAC) protocol were provided to school children in Ireland (Republic and Northern Ireland). In the Republic of Ireland, all children in classes largely aged 13–14 years from 30 post‐primary schools were selected by random sampling stratified by school size, composition and Health Board in Spring 1995. In Northern Ireland, all children largely aged 13–14 years of age from 26 post‐primary schools were selected by random sampling stratified by school type, composition and Education and Library Board in Spring 1996.
Results Questionnaires were completed by 2364 children from Northern Ireland and 2671 from the Republic, about 90% of those eligible to participate. The prevalences of wheeze at various levels of severity, of diagnosed asthma and of treated wheeze were very similar in Northern Ireland and the Republic of Ireland. A significant proportion of those reporting more severe symptomatology (four or more attacks of wheeze in the past 12 months and/or one or more nights disturbed and/or moderate or greater disruption of daily activities and/or speech restriction due to wheeze) had been neither diagnosed nor treated for asthma (20–37%). To investigate the determinants of the more severe symptomatology of asthma or treated wheeze a series of stepwise multiple regression analyses was performed. A history of atopy, cigarette smoking, the possession of a furry pet other than a dog or cat and age were each independently associated with severe wheeze, whilst atopy, a furry pet (as above) and gender were each independently associated with asthma or treated wheeze.
Conclusions Cigarette smoking is closely associated with the reporting of significant respiratory symptoms together with atopy and exposure to furry pets. Some 20–37% of severe symptoms were neither diagnosed nor treated as asthma.
We present optical and infrared monitoring data of SN 2012hn collected by the Public ESO Spectroscopic Survey for Transient Objects (PESSTO). We show that SN 2012hn has a faint peak magnitude (MR ~ ...-15.7) and shows no hydrogen and no clear evidence for helium in its spectral evolution. Instead, we detect prominent Ca II lines at all epochs, which relates this transient to previously described 'Ca-rich' or 'gap' transients. However, the photospheric spectra (from -3 to +32 d with respect to peak) of SN 2012hn show a series of absorption lines which are unique, and a red continuum that is likely intrinsic rather than due to extinction. Lines of Ti II and Cr II are visible. This may be a temperature effect, which could also explain the red photospheric colour. A nebular spectrum at +150d shows prominent CaII, OI, CI and possibly MgI lines which appear similar in strength to those displayed by core-collapse SNe. To add to the puzzle, SN 2012hn is located at a projected distance of 6 kpc from an E/S0 host and is not close to any obvious starforming region. Overall SN 2012hn resembles a group of faint H-poor SNe that have been discovered recently and for which a convincing and consistent physical explanation is still missing. They all appear to explode preferentially in remote locations offset from a massive host galaxy with deep limits on any dwarf host galaxies, favouring old progenitor systems. SN 2012hn adds heterogeneity to this sample of objects. We discuss potential explosion channels including He-shell detonations and double detonations of white dwarfs as well as peculiar core-collapse SNe.