We first present the implementation and validation of the SuSAv2-MEC 1p1h and 2p2h models in the GENIE neutrino-nucleus interaction event generator and a comparison of the subsequent predictions to ...measurements of lepton and hadron kinematics from the T2K experiment. These predictions are also compared to those of other available models in GENIE. We further compare semi-inclusive predictions of the implemented 1p1h model to those of the microscopic model on which SuSAv2 is based-relativistic mean field-to begin to test the validity of widely used "factorization" assumptions employed by generators to predict hadron kinematics from inclusive input models. The results highlight that a more precise treatment of hadron kinematics in generators is essential in order to attain the few-% level uncertainty on neutrino interactions necessary for the next generation of accelerator-based long-baseline neutrino oscillation experiments.
We present our recent progress on the relativistic modeling of electron-nucleus reactions and compare our predictions with inclusive C super(12)(e, e') experimental data in a wide kinematical region. ...The model, originally based on the superscaling phenomenon shown by electron-nucleus scattering data, has recently been improved through the inclusion of relativistic mean field theory effects that take into account the enhancement of the quasielastic transverse scaling function compared with its longitudinal counterpart. In this work, we extend the model to include the complete inelastic spectrum-resonant, nonresonant and deep inelastic scattering. We also discuss the impact of meson-exchange currents through the analysis of two-particle two-hole contributions to electromagnetic response functions evaluated within the framework of the relativistic Fermi gas, considering for the first time not only the transverse but also the longitudinal channel. The results show quite good agreement with data over the whole range of energy transfer, including the dip region between the quasielastic peak and the Delta resonance.
The extraction of neutrino mixing parameters from accelerator-based neutrino-oscillation experiments relies on proper modeling of neutrino-nucleus scattering processes using neutrino interaction ...event generators. Experimental tests of these generators are difficult due to the broad range of neutrino energies produced in accelerator-based beams and the low statistics of current experiments. Here we overcome these difficulties by exploiting the similarity of neutrino and electron interactions with nuclei to test neutrino event generators using high-precision inclusive electron-scattering data. To this end, we revised the electron-scattering mode of the genie event generator (e-genie) to include electron-nucleus bremsstrahlung radiation effects and to use, when relevant, the exact same physics models and model parameters, as the standard neutrino-scattering version. We also implemented new models for quasielastic (QE) scattering and meson exchange currents (MECs) based on the theory-inspired super scaling approach SuSAv2. Comparing the new e-genie predictions with inclusive electron-scattering data, we find an overall adequate description of the data in the QE- and MEC-dominated lower energy transfer regime, especially when using the SuSAv2 models. Higher energy transfer interactions, which are dominated by resonance production, are still not well modeled by e-genie.
To assess in patients with 1–10 brain metastases, each of which has been treated by neurosurgery or stereotactic radiosurgery, whether hippocampal sparing whole brain radiotherapy (HS-WBRT) better ...spares neurocognitive function (NCF) than standard WBRT. Further, to assess whether a phase III randomised trial of HS-WBRT would be feasible in the UK.
A multicentre, randomised, open label phase II trial was undertaken, randomising patients to 30Gy in 10 fractions of WBRT or HS-WBRT. The primary endpoint was decline in Total recall using Hopkins Verbal Learning Test Revised (HVLT-R) at 4 months post treatment. To assess this, we aimed to recruit 84 patients over 3 years. Secondary endpoints included further measures of NCF, quality of life, duration of functional independence, local control of treated metastases, development of new metastases, disease control within the hippocampal regions, overall survival, steroid and antiepileptic medication requirements, and toxicity.
The trial closed prematurely due to slower than anticipated recruitment. From April 2016 to January 2018, 23 patients were randomised. Follow up was a median of 25 months. Fifteen patients (6 WBRT, 9 HS-WBRT) were assessed for the primary endpoint; of these, 1 in each arm experienced significant decline in the 4-month HVLT-R Total recall score (p = 0.8). Patients in the HS-WBRT arm experienced less insomnia (p < 0.01) and drowsiness (p < 0.01). There were no differences in other secondary endpoints.
A phase III randomised trial of HS-WBRT was shown not to be feasible at this time in the UK. As most randomised trials of HS-WBRT reported to date share common endpoints, including NCF, an individual patient data meta-analysis should be undertaken.
•Changes in clinical practice away from whole brain radiotherapy necessitated early trial closure.•No significant differences in any neurocognitive outcomes were observed.•Compliance with serial neurocognitive function assessments was high.•Patients in the hippocampal sparing arm had significantly less insomnia and drowsiness.
We compare the results of the SuSAv2 model including meson-exchange currents (MEC) with the recent measurement of the quasielasticlike double differential antineutrino cross section on a hydrocarbon ...performed by the MINERvA Collaboration C. E. Patrick et al. (MINERvA Collaboration), Phys. Rev. D 97, 052002 (2018). The relativistic nature of the model makes it suitable to describe these data, which correspond to a mean beam energy of 3.5 GeV. The standard SuSAv2 model predictions agree well with the data without needing any additional or tuned parameter. The role of longitudinal MEC is non-negligible and improves the agreement with the data. We also consider the impact of different treatments of the Δ-resonance propagator in the two-body currents on the data comparison.
In this review we compile results on interactions above and below ground and food web functioning in an arid environment at the Baza Basin, in the Iberian southeast. Our data reveal that herbivory is ...difficult to estimate in our system. Some herbivores (rabbits) and granivores (
Messor ants) create nutrient and detritus-rich patches, with important effects on the diversity and abundance of species both above and below ground. Fluctuations of prey availability, especially those caused by changes in their circadian rhythms, provoke seasonal migrations and omnivory in predators. We also present experimental evidence of the effects of interactions between aboveground and belowground macroarthropods on litter degradation; belowground detritivores are responsible for a high percentage of ground surface litter decomposition. We demonstrate that belowground herbivores and decomposers can dramatically change aboveground multitrophic interactions. Finally, we identify the biotic and abiotic factors controlling aboveground and belowground macrofaunal distribution at a broad scale. We conclude that trophic interactions in this semi-arid area are numerous and complex with many of the interactions involving more than two or three organisms. The interactions between above- and belowground organisms added complexity to this system. These habitats in which organisms deal with extreme abiotic conditions promote odd interactions resulting in an increase of biodiversity. Finally, despite the large research effort devoted to understanding food web structure and dynamics in this area recently, our state of knowledge is still far from providing a complete picture of interactions and their implications in the regulation and functioning of the system.
► Review of above- and belowground trophic interactions in an arid system in Spain. ► Rabbits and ants create nutrient patches that modulate above and belowground biodiversity. ► Fluctuations of prey availability provoke seasonal migrations and omnivory in predators. ► Belowground herbivores and decomposers change aboveground multitrophic interactions.
We present the results of semi-inclusive neutrino-nucleus cross sections within the plane wave impulse approximation (PWIA) for three nuclear models: relativistic Fermi gas, independent-particle ...shell model, and natural orbital shell model in comparison with the available CC 0 π measurements from the T2K, MINER ν A , and MicroBooNE collaborations where a muon and at least one proton are detected in the final state. Results are presented as a function of the momenta and angles of the final particles, as well as in terms of the imbalances between proton and muon kinematics. The present semi-inclusive formalism is based on fully relativistic microscopic calculations and numerical integrations to produce both lepton and hadron kinematics without relying on further approximations. The analysis reveals that contributions beyond PWIA are crucial to explain the experimental measurements and that the study of correlations between final-state proton and muon kinematics can provide valuable information on relevant nuclear effects such as the Fermi motion and final-state interactions.