The adsorption of Acid blue 25, basic blue 9, basic violet 3, Pb2+, Ni2+, Zn2+ and Cd2+ ions has been studied in single and dye–metal binary solutions using two mineral materials: Clinoptilolite (CL) ...and ER (Erionite). These zeolites were characterized by FT-IR spectroscopy; potentiometric titration and nitrogen adsorption isotherms at 77 K to obtain their textural parameters. Results indicated that ER has an acidic character and a high specific surface (401 m2 g−1) in contrast with the zeolite CL (21 m2 g−1). Surprisingly, the removal of dyes was very similar for the two zeolites and they showed a considerable selectivity by the basic dyes in comparison with the acid dyes. In the case of heavy metals, ER was more effective in the adsorption process showing a selectivity of: Pb2+ > Ni2+ > Zn2+ > Cd2+. In the multicomponent adsorption experiments an antagonistic effect was observed in the removal of basic dyes and heavy metals. Particularly, the adsorbed amount of basic violet 3 decreased more significantly when the heavy metals are presents in contrast with the basic blue 9.
► Adsorption of dyes and heavy metals was studied in single and dye–metal solutions. ► Two natural zeolites: Clinoptilolite and Erionite were used as sorbents. ► The zeolites are more efficient to remove cationic dyes. ► In dye–metal binary solutions one antagonistic effect was observed in the adsorption of dyes and heavy metals.
ABSTRACT The "main sequence of galaxies"-defined in terms of the total star formation rate versus the total stellar mass M*-is a well-studied tight relation that has been observed at several ...wavelengths and at different redshifts. All earlier studies have derived this relation from integrated properties of galaxies. We recover the same relation from an analysis of spatially resolved properties, with integral field spectroscopic (IFS) observations of 306 galaxies from the CALIFA survey. We consider the SFR surface density in units of log(M yr−1 Kpc−2) and the stellar mass surface density in units of log(M Kpc−2) in individual spaxels that probe spatial scales of 0.5-1.5 Kpc. This local relation exhibits a high degree of correlation with small scatter ( = 0.23 dex), irrespective of the dominant ionization source of the host galaxy or its integrated stellar mass. We highlight (i) the integrated star formation main sequence formed by galaxies whose dominant ionization process is related to star formation, for which we find a slope of 0.81 0.02; (ii) for the spatially resolved relation obtained with the spaxel analysis, we find a slope of 0.72 0.04; and (iii) for the integrated main sequence, we also identified a sequence formed by galaxies that are dominated by an old stellar population, which we have called the retired galaxies sequence.
Context. The star formation rate (SFR) is one of the main parameters used to analyze the evolution of galaxies through time. The need for recovering the light reprocessed by dust commonly requires ...the use of low spatial resolution far-infrared data. Recombination line luminosities provide an alternative, although uncertain dust-extinction corrections based on narrowband imaging or long-slit spectroscopy have traditionally posed a limit to their applicability. Integral field spectroscopy (IFS) is clearly the way to overcome this kind of limitation. Aims. We obtain integrated Hα, ultraviolet (UV) and infrared (IR)-based SFR measurements for 272 galaxies from the CALIFA survey at 0.005 <z< 0.03 using single-band and hybrid tracers. We aim to determine whether the extinction-corrected Hα luminosities provide a good measure of the SFR and to shed light on the origin of the discrepancies between tracers. Updated calibrations referred to Hα are provided. The well-defined selection criteria and large statistics allow us to carry out this analysis globally and split by properties, including stellar mass and morphological type. Methods. We derive integrated, extinction-corrected Hα fluxes from CALIFA, UV surface and asymptotic photometry from GALEX and integrated WISE 22 μm and IRAS fluxes. Results. We find that the extinction-corrected Hα luminosity agrees with the hybrid updated SFR estimators based on either UV or Hα plus IR luminosity over the full range of SFRs (0.03−20 M⊙ yr-1). The coefficient that weights the amount of energy produced by newly-born stars that is reprocessed by dust on the hybrid tracers, aIR, shows a large dispersion. However, this coefficient does not became increasingly small at high attenuations, as expected if significant highly-obscured Hα emission were missed, i.e., after a Balmer decrement-based attenuation correction is applied. Lenticulars, early-type spirals, and type-2 AGN host galaxies show smaller coefficients because of the contribution of optical photons and AGN to dust heating. Conclusions. In the local Universe, the Hα luminosity derived from IFS observations can be used to measure SFR, at least in statistically-significant, optically-selected galaxy samples, once stellar continuum absorption and dust attenuation effects are accounted for. The analysis of the SFR calibrations by galaxies properties could potentially be used by other works to study the impact of different selection criteria in the SFR values derived, and to disentangle selection effects from other physically motivated differences, such as environmental or evolutionary effects.
We use optical integral field spectroscopy (IFS) of nearby supernova (SN) host galaxies provided by the Calar Alto Legacy Integral Field Area (CALIFA) Survey with the goal of finding correlations in ...the environmental parameters at the location of different SN types. In this first study of a series we focus on the properties related with star formation (SF). We recover the sequence in association of different SN types to the star-forming regions by using several indicators of the ongoing and recent SF related to both the ionized gas and the stellar populations. We estimate that the low-mass galaxies produce ten times fewer SNe Ia and three times fewer CC SNe than the high-mass group. Therefore the ratio between the number of CC SNe and SNe Ia is expected to increase with decreasing galaxy mass. CC SNe tend to explode at positions with younger stellar populations than the galaxy average, but the galaxy properties at SNe Ia locations are one average the same as the global galaxy properties.
•The average diameter of the ZnO and ZnO:Eu nanoparticles was in the range 14 a 20 nm.•Methylene blue degradation with ZnO and ZnO:Eu.•ZnO nanoparticles is not necessary to heat treatment to activate ...the photoactive.•1.62% Eu-ZnO has highest photocatalytic activity.
Photocatalysis using semiconductor materials, such as ZnO and TiO2, allows the degradation of organic compounds through the redox process when it is irradiated by UV or solar light. In the present work the nanoparticles of ZnO and ZnO:Eu were synthesized using the forced-hydrolysis method. It was determined the effect of the heat treatment on ZnO nanoparticles at 400, 450 and 500 °C. The percentages of doped ZnO with Europium (Eu) was 0.97, 1.62 and 3% weight. The materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), infrared spectroscopy (FT-IR), visible ultraviolet spectroscopy (UV–vis) and the photocatalytic activity was evaluated to degradation of methylene blue (MB). The ZnO:Eu with 1.62% show MB degradation of 99.3% in 80 min.
We use optical integral field spectroscopy (IFS) of nearby supernova (SN) host galaxies (0.005 <z< 0.03) provided by the Calar Alto Legacy Integral Field Area (CALIFA) Survey with the goal of finding ...correlations in the environmental parameters at the location of different SN types. In this first study of a series we focus on the properties related with star formation (SF). We recover the sequence in association of different SN types to the star-forming regions by using several indicators of the ongoing and recent SF related to both the ionized gas and the stellar populations. While the total ongoing SF is on average the same for the three SN types, SNe Ibc/IIb tend to occur closer to star-forming regions and in higher SF density locations than SNe II and SNe Ia; the latter shows the weakest correlation. SNe Ia host galaxies have masses that are on average ~0.3−0.8 dex higher than those of the core collapse (CC) SNe hosts because the SNe Ia hosts contain alarger fraction of old stellar populations. Using the recent SN Ia delay-time distribution and the SFHs of the galaxies, we show that the SN Ia hosts in our sample are expected to produce twice as many SNe Ia as the CC SN hosts. Since both types occur in hosts with a similar SF rate and hence similar CC SN rate, this can explain the mass difference between the SN Ia and CC SN hosts, and reinforces the finding that at least part of the SNe Ia originate from very old progenitors. By comparing the mean SFH of the eight least massive galaxies with that of the massive SF SN Ia hosts, we find that the low-mass galaxies formed their stars during a longer time (0.65%, 24.46%, and 74.89% in the intervals 0–0.42 Gyr, 0.42–2.4 Gyr, and >2.4 Gyr, respectively) than the massive SN Ia hosts (0.04%, 2.01%, and 97.95% in these intervals). We estimate that the low-mass galaxies produce ten times fewer SNe Ia and three times fewer CC SNe than the high-mass group. Therefore the ratio between the number of CC SNe and SNe Ia is expected to increase with decreasing galaxy mass. CC SNe tend to explode at positions with younger stellar populations than the galaxy average, but the galaxy properties at SNe Ia locations are one average the same as the global galaxy properties.
The essential oils of Citrus sinensis and Citrus latifolia showed antimycotic activity against Candida spp. isolated from the oral cavity; they are neither mutagenic on the Ames test nor cytotoxic. ...Their main components are R-(+)-limonene, β-thujene, α-myrcene and γ-terpinene. The aim of this work was to evaluate their antimutagenic and antioxidant capacities. Antimutagenic properties were evaluated against MNNG and ENNG on S. typhimurium TA100; against 2AA on strain TA98 and in front of 4NQO and NOR on strain TA102. Both were antimutagenic against MNNG (p < 0.001) but only C. latifolia was antimutagenic against ENNG (p < 0.001). Both presented antimutagenic activity against 2AA (p < 0.001). They were antioxidant against the ROS-generating compound 4NQO (p < 0.001) and the antibiotic NOR (p < 0.001). In the antioxidant evaluation, the activity in DPPH assay was in a range of 6-23% for C. sinensis and of 22-71% for C. latifolia. Both were antioxidant compared with BHT in β-carotene bleaching assay and were able to decreased apoptosis in HaCat cells stimulated with H
O
. The levels of intracellular superoxide ion were lower in the presence of both oils. In conclusion, the essential oils of C. sinensis and C. latifolia are antimutagenic against at least three types of mutagens and have antioxidants properties.
In
x
Ga
1
-
x
As
y
Sb
1
-
y
epilayers with a fixed In content of
x
= 0.145 were grown on GaSb(100) substrates using liquid-phase epitaxy (LPE). The lattice mismatch between the quaternary epilayers ...and substrates was analyzed for different As contents (
y
) by X-ray
ω
-2
θ
. Epilayers with As content between
y
= 0.120 and
y
= 0.124 exhibited a positive lattice mismatch, leading to compressive strain. These samples showed a high crystalline quality and flat surfaces, as confirmed by high-resolution X-ray diffraction (HR-XRD) and atomic force microscopy (AFM). Quaternary alloys with As content between
y
= 0.133 and
y
= 0.141 displayed a negative lattice mismatch, resulting in tensile strain. Structural defects in these samples were evidenced by HR-XRD and on AFM micrographs. Raman measurements also revealed that lateral strain has a direct impact on the intensities of the LO-like, phonon–plasmon and disorder-activated longitudinal acoustic modes. For all In
x
Ga
1
-
x
As
y
Sb
1
-
y
films, photoluminescence (PL) spectra showed a bound exciton (BE) transition, with additional features observed in samples under tensile strain, indicating the involvement of native defect centers and donor–acceptor pairs. This study provides new insights into the effect of lateral strain on the crystalline and surface quality, and optical properties of quaternary alloys, relevant for novel optoelectronic applications.
Purpose
Intestinal dysbiosis has emerged as a biomarker of response to immune checkpoint inhibitors (ICIs). It can be caused by antibiotics, although it may also result from the use of other drugs ...that have been studied to a lesser extent. The objective of our study was to analyze the association between the use of potentially dysbiosis-related drugs and survival in patients treated with ICIs in the clinical practice.
Materials and methods
A retrospective, multicenter, cohort study was conducted. Clinicopathological variables were collected and the concomitant use of drugs was analyzed. A descriptive analysis of variables and overall survival, estimated by the Kaplan–Meier method, was performed, and association with various independent variables was assessed using Cox regression.
Results
We included 253 patients, mainly with non-small cell lung cancer and melanoma. The most commonly used drugs were acid reducers, prescribed to 55.3% of patients, followed by corticosteroids (37.9%), anxiolytic drugs (35.6%), and antibiotics (20.5%). The use of acid reducers (9 vs. 18 months,
P
< .0001), antibiotics (7 vs. 15 months,
P
< .017), anxiolytic drugs (8 vs. 16 months,
P
< .015), and corticosteroids (6 vs. 19 months,
P
< .00001) was associated with poorer overall survival. Furthermore, the greater the number of drugs used concomitantly with ICIs, the higher the risk of death (1 drug: hazard ratio, 1.88; CI 95%, 1.07–3.30; 4 drugs: hazard ratio, 4.19; CI9 5%, 1.77–9.92;
P
< .001).
Conclusion
Response to ICIs may be influenced by the use of drugs that lead to intestinal dysbiosis. Although a confirmatory prospective controlled study is required, our findings should be taken into account when analyzing ICI efficacy.
HIV-2 is a neglected virus despite estimates of 1-2 million people being infected worldwide. The virus is naturally resistant to some antiretrovirals used to treat HIV-1 and therapeutic options are ...limited for patients with HIV-2.
In this retrospective observational study, we analysed all HIV-2-infected individuals treated with integrase strand transfer inhibitors (INSTIs) recorded in the Spanish HIV-2 cohort. Demographics, treatment modalities, laboratory values, quantitative HIV-2 RNA and CD4 counts as well as drug resistance were analysed.
From a total of 354 HIV-2-infected patients recruited by the Spanish HIV-2 cohort as of December 2017, INSTIs had been given to 44, in 18 as first-line therapy and in 26 after failing other antiretroviral regimens. After a median follow-up of 13 months of INSTI-based therapy, undetectable viraemia for HIV-2 was achieved in 89% of treatment-naive and in 65.4% of treatment-experienced patients. In parallel, CD4 gains were 82 and 126 cells/mm3, respectively. Treatment failure occurred in 15 patients, 2 being treatment-naive and 13 treatment-experienced. INSTI resistance changes were recognized in 12 patients: N155H (5), Q148H/R (3), Y143C/G (3) and R263K (1).
Combinations based on INSTIs are effective and safe treatment options for HIV-2-infected individuals. However, resistance mutations to INSTIs are selected frequently in failing patients, reducing the already limited treatment options.
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