Introduction
New tools have been developed to distinguish the COVID‐19 diagnosis from other viral infections presenting similar symptomatology and mitigate the lack of sensitivity of molecular ...testing. We previously identified a specific “sandglass” aspect on the white blood cells (WBC) scattergram of COVID‐19 patients, as a highly reliable COVID‐19 screening test (sensitivity: 85.9%, specificity: 83.5% and positive predictive value: 94.3%). We then decided to validate our previous data in a multicentric study.
Methods
This retrospective study involved 817 patients with flu‐like illness, among 20 centers, using the same CBC instrument (XN analyzer, SYSMEX, Japan). After training, one specialist per center independently evaluated, under the same conditions, the presence of the “sandglass” aspect of the WDF scattergram, likely representing plasmacytoid lymphocytes.
Results
Overall, this approach showed sensitivity: 59.0%, specificity: 72.9% and positive predictive value: 77.7%. Sensitivity improved with subgroup analysis, including in patients with lymphopenia (65.2%), patients presenting symptoms for more than 5 days (72.3%) and in patients with ARDS (70.1%). COVID‐19 patients with larger plasmacytoid lymphocyte cluster (>15 cells) more often have severe outcomes (70% vs. 15% in the control group).
Conclusion
Our findings confirm that the WBC scattergram analysis could be added to a diagnostic algorithm for screening and quickly categorizing symptomatic patients as either COVID‐19 probable or improbable, especially during COVID‐19 resurgence and overlapping with future influenza epidemics. The observed large size of the plasmacytoid lymphocytes cluster appears to be a hallmark of COVID‐19 patients and was indicative of a severe outcome. Furthers studies are ongoing to evaluate the value of the new hematological parameters in combination with WDF analysis.
Temps et migrations Mercier, Delphine; Chiffoleau, Sylvia; Thoemmes, Jens
Temporalités/Temporalités,
07/2021, Letnik:
33, Številka:
33
Journal Article
Odprti dostop
Ce dossier interroge la question des temporalités articulée à celle des migrations. Nous faisons le constat que si le « temps » est fréquemment mobilisé dans les titres d’articles ou d’ouvrages sur ...les migrations, force est de constater que ce concept reste souvent à l’état d’illustration. Le dernier ouvrage sur les migrations qui a utilisé le terme « temporalités » faisait ainsi part du constat suivant : « les temporalités constituent une entrée courante de l’approche des migrations internat...
ABSTRACT This article proposes an analytical approach to conflicts and policy-making related to urban water management based on multi-level policy coalitions. This is necessary to articulate four ...main issues. First, the repositioning of social and political struggles for access to water, along with policy variables. Second, the analysis of the effects of ecological transition, including climate change. Third, the reincorporation of these struggles and challenges in a multi-level approach. Finally, the enquiry into the apparent contradiction, in contemporary policymaking. The article proposes a definition of multi-level coalitions as collective preference systems that influence the content of policies (ideas/advocacy, decisions, policy tools) and their implementation, groups of actors that arise from engagement in policy issues. In the first section, the article presents the objectives of research on urban water management in the Americas, within the framework of which this analytical approach by multi-level coalitions is fashioned. In the second section, the article details four analytical issues. In the third section, it gives a definition of multi-level coalitions.
RESUMEN Este artículo propone un abordaje analítico, basado en coaliciones de política multinivel, sobre conflictos y policy-making relacionados con el manejo urbano del agua. Esto es necesario en pos de articular cuatro asuntos principales. En primer lugar, el reposicionamiento de las luchas sociales y políticas por el acceso al agua, junto a variables políticas. Luego, el análisis de los efectos de la transición ecológica, incluyendo al cambio climático. Terceramente, la reincorporación de dichas luchas y desafíos al abordaje multinivel. Y por último, la evidente contradicción en la formulación contemporánea de políticas. El trabajo sugiere una definición de coaliciones multinivel: sistemas colectivos de preferencias que influencian el contenido de políticas (ideas/defensa, decisiones, herramientas políticas) y su implementación; grupos de actores que surgen al involucrarse con los asuntos políticos. En la primera sección, el artículo presenta los objetivos de la investigación en manejo urbano del agua en las Américas, dentro del marco de trabajo del abordaje de coaliciones multinivel. En la segunda parte, se detallan los cuatro temas analíticos previamente mencionados. Y en la sección final, el trabajo brinda una definición de las coaliciones multinivel.
RESUMO Este artigo propõe uma abordagem analítica para conflitos e elaboração de políticas relacionadas com a gestão das águas urbanas com base em coligações políticas multi-nível. Isso é necessário para articular quatro questões principais: em primeiro lugar, o reposicionamento das lutas sociais e políticas para o acesso à água, juntamente com variáveis de políticas; em segundo lugar, a análise dos efeitos de transição ecológica, incluindo as alterações climáticas; em terceiro lugar, a reincorporação dessas lutas e os desafios no contexto de uma abordagem multi-nível, e por último, a pesquisa sobre a aparente contradição, na formulação de contemporânea de políticas. O artigo propõe uma definição de coalizões multi-níveis como sistemas de preferências coletivos que influenciam o conteúdo das políticas (ideias / defesa, decisões, instrumentos de políticas) e a respectiva implementação, grupos de atores que surgem de envolvimento em questões relacionadas com as políticas. Na primeira seção, o artigo apresenta os objetivos da pesquisa sobre a gestão das águas urbanas nas Américas, no marco conceitual no qual esta abordagem analítica por coalizões multi-nível é desenvolvida. Na segunda seção, o artigo detalha quatro questões analíticas. Na terceira seção, se apresenta uma definição de coalizões multi-nível.
They work in the street, day and night... their specificity, their work is circumscribed to the border, to its passage, where the street is transformed into multiple barriers, in the form of a ...horizontal mille-feuille. Globalisation is not only a story of capital and companies relocating to benefit from cheap labour, but globalisation is also a process of construction or consolidation of professions that emerge or are declined in particular in the appropriation of skills and know-how relating to border uses and devices. Within the framework of these new rules, individuals have been able to or have had to renegotiate professional spaces or create new ones. These workers, border entrepreneurs, thus move between two spaces that are particularly strong in terms of cost differentials in order to buy products, resell them and move them around. They are also customs officers, state officials who know the rules and use their official position to provide “à la carte” services, creating and consolidating clientelistic border crossing practices in the literal and figurative sense. In short, the list is long and involves a whole series of professions, some of which are “odd jobs” to get themselves out of precariousness. In recent years, these professions have been built around border skills and practices, and the harder the borders become, the more the skills in this area increase and are negotiated. These “border makers’ contribute for the most part to the fluidity and circumvention of the rules, and some of them have become indispensable for border users, who are often captive to these intermediaries. We therefore propose, thanks to this iconographic material, to give an account of the professions that are practised, in particular by making the link between this regionalisation of the economies of the South, which are combined by the construction of specific know-how that contributes to constituting new professions and even new professionalities that we call “border makers”.
Ce numéro spécial consacré au Mexique rassemble un ensemble de contributions fédérées par la volonté de proposer quelques « coups de sonde » au sein de secteurs et de métiers susceptibles d’éclairer, ...autant que faire se peut, la relation entre formation et emploi. Le lecteur y trouvera un article dédié aux salariés du secteur de l’énergie et de l’extraction, deux travaux portant sur ces métiers du « développement humain » que sont l’éducation et la santé (infirmerie), deux études consacrées a...
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