NASA's OSIRIS-REx spacecraft collected samples from carbonaceous near-Earth asteroid (101955) Bennu on October 20, 2020, and will deliver them to the Earth on September 24, 2023. The samples will be ...processed at the NASA Johnson Space Center (JSC), where most of the sample collection will be subsequently curated in a new cleanroom suite. The spacecraft collected loose regolith two ways: in a bulk sample chamber capable of holding up to 2 kg, and on industrial Velcro “contact pads” intended to collect small particles at the surface. Included in the JSC collection will be the bulk sample, the contact pads, contamination-monitoring witness plates, and supporting hardware. Planning for the curation of the samples and hardware started at the earliest phase of proposal development and continued in parallel with project development and execution. Because a major mission goal is characterization of organic compounds in the Bennu samples, extra effort was spent in the design stage to ensure a clean curation environment. Here, we describe the preparations to receive the sample, including the design, construction, outfitting, and monitoring of the cleanrooms at JSC; the planned recovery of the sample-containing capsule when it lands on Earth; and the approach to characterizing and cataloging the samples. These curation efforts will result in the distribution of pristine Bennu samples from JSC to the OSIRIS-REx science team, international partners, and the global scientific community for years to come.
We describe a search underway for periodic gravitational waves from the central compact object in the supernova remnant Cassiopeia A. The object is the youngest likely neutron star in the Galaxy. Its ...position is well known, but the object does not pulse in any electromagnetic radiation band and thus presents a challenge in searching the parameter space of frequency and frequency derivatives. We estimate that a fully coherent search can, with a reasonable amount of time on a computing cluster, achieve a sensitivity at which it is theoretically possible (though not likely) to observe a signal even with the initial LIGO noise spectrum. Cassiopeia A is only the second object after the Crab pulsar for which this is true. The search method described here can also obtain interesting results for similar objects with current LIGO sensitivity.
OSIRIS-REx will return pristine samples of carbonaceous asteroid Bennu. This article describes how pristine was defined based on expectations of Bennu and on a realistic understanding of what is ...achievable with a constrained schedule and budget, and how that definition flowed to requirements and implementation. To return a pristine sample, the OSIRIS-REx spacecraft sampling hardware was maintained at level 100 A/2 and less than 180 ng/cm(exp 2) of amino acids and hydrazine on the sampler head through precision cleaning, control of materials, and vigilance. Contamination is further characterized via witness material exposed to the spacecraft assembly and testing environment as well as in space. This characterization provided knowledge of the expected background and will be used in conjunction with archived spacecraft components for comparison with the samples when they are delivered to Earth for analysis. Most of all, the cleanliness of the OSIRIS-REx spacecraft was achieved through communication among scientists, engineers, managers, and technicians.
Traditional quantitative coronary angiography is performed on two-dimensional (2-D) projection views. These views are chosen by the angiographer to minimize vessel overlap and foreshortening. With ...2-D projection views that are acquired in this nonstandardized fashion, however, there is no way to know or estimate how much error occurs in the QCA process. Furthermore, coronary arteries possess a curvilinear shape and undergo a cyclical deformation due to their attachment to the myocardium. Therefore, it is necessary to obtain three-dimensional (3-D) information to best describe and quantify the dynamic curvilinear nature of the human coronary artery. Using a patient-specific 3-D coronary reconstruction algorithm and routine angiographic images, a new technique is proposed to describe: (1) the curvilinear nature of 3-D coronary arteries and intracoronary devices; (2) the magnitude of the arterial deformation caused by intracoronary devices and due to heart motion; and (3) optimal view(s) with respect to the desired "pathway" for delivering intracoronary devices.
The objective of this paper is to summarise what is known about key trends and developments in working time across Europe. The European Region analysed in this paper includes not only the 27 current ...member states of the European Union (EU), but extends even beyond its borders. This paper review trends and patterns in working hours in the broadest range of countries possible given data limitations (especially outside the EU), with a focus on: average weekly hours of work and the proportion of workers working 'excessively long hours' (defined as usual working hours of 48 or more per week); developments regarding one unique form of working time arrangement, part-time work, with a focus on the incidence of part-time work in each country, changes in this incidence over time, the female share of part-time employment and issues related to the quality of part-time jobs; and finally considers trends in the organisation of working time across Europe, with a focus on the incidence of non-standard work schedules (e.g. night work and weekend work) and shift work, as well as the extent to which various types of flexible working time arrangements are being deployed in individual enterprises. Finally, the paper presents some policy suggestions within a broad framework designed to advance the International Labour Organisation (ILO) concept of decent work in the area of working time.
Trypanosoma cruzi marinkellei is a bat-associated parasite of the subgenus Schizotrypanum and it is regarded as a T. cruzi subspecies. Here we report a draft genome sequence of T. c. marinkellei and ...comparison with T. c. cruzi. Our aims were to identify unique sequences and genomic features, which may relate to their distinct niches.
The T. c. marinkellei genome was found to be ~11% smaller than that of the human-derived parasite T. c. cruzi Sylvio X10. The genome size difference was attributed to copy number variation of coding and non-coding sequences. The sequence divergence in coding regions was ~7.5% between T. c. marinkellei and T. c. cruzi Sylvio X10. A unique acetyltransferase gene was identified in T. c. marinkellei, representing an example of a horizontal gene transfer from eukaryote to eukaryote. Six of eight examined gene families were expanded in T. c. cruzi Sylvio X10. The DGF gene family was expanded in T. c. marinkellei. T. c. cruzi Sylvio X10 contained ~1.5 fold more sequences related to VIPER and L1Tc elements. Experimental infections of mammalian cell lines indicated that T. c. marinkellei has the capacity to invade non-bat cells and undergo intracellular replication.
Several unique sequences were identified in the comparison, including a potential subspecies-specific gene acquisition in T. c. marinkellei. The identified differences reflect the distinct evolutionary trajectories of these parasites and represent targets for functional investigation.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
We present direct upper limits on gravitational wave emission from the Crab pulsar using data from the first 9 months of the fifth science run of the Laser Interferometer Gravitational-wave ...Observatory (LIGO). These limits are based on two searches. In the first we assume that the gravitational wave emission follows the observed radio timing, giving an upper limit on gravitational wave emission that beats indirect limits inferred from the spin-down and braking index of the pulsar and the energetics of the nebula. In the second we allow for a small mismatch between the gravitational and radio signal frequencies and interpret our results in the context of two possible gravitational wave emission mechanisms.
We analyzed the available LIGO data coincident with GRB 070201, a short- duration, hard-spectrum -ray burst (GRB) whose electromagnetically determined sky position is coincident with the spiral arms ...of the Andromeda galaxy (M31). Possible progenitors of such short, hard GRBs include mergers of neutron stars or a neutron star and a black hole, or soft -ray repeater (SGR) flares. These events can be accompanied by gravitational-wave emission. No plausible gravitational-wave candidates were found within a 180 s long window around the time of GRB 070201. This result implies that a compact binary progenitor of GRB 070201, with masses in the range image and image, located in M31 is excluded at >99% confidence. If the GRB 070201 progenitor was not in M31, then we can exclude a binary neutron star merger progenitor with distance image Mpc, assuming random inclination, at 90% confidence. The result also implies that an unmodeled gravitational-wave burst from GRB 070201 most probably emitted less than image (image ergs) in any 100 ms long period within the signal region if the source was in M31 and radiated isotropically at the same frequency as LIGO's peak sensitivity (image Hz). This upper limit does not exclude current models of SGRs at the M31 distance.
Abstract
NASA's OSIRIS‐REx spacecraft collected samples from carbonaceous near‐Earth asteroid (101955) Bennu on October 20, 2020, and will deliver them to the Earth on September 24, 2023. The samples ...will be processed at the NASA Johnson Space Center (JSC), where most of the sample collection will be subsequently curated in a new cleanroom suite. The spacecraft collected loose regolith two ways: in a bulk sample chamber capable of holding up to 2 kg, and on industrial Velcro “contact pads” intended to collect small particles at the surface. Included in the JSC collection will be the bulk sample, the contact pads, contamination‐monitoring witness plates, and supporting hardware. Planning for the curation of the samples and hardware started at the earliest phase of proposal development and continued in parallel with project development and execution. Because a major mission goal is characterization of organic compounds in the Bennu samples, extra effort was spent in the design stage to ensure a clean curation environment. Here, we describe the preparations to receive the sample, including the design, construction, outfitting, and monitoring of the cleanrooms at JSC; the planned recovery of the sample‐containing capsule when it lands on Earth; and the approach to characterizing and cataloging the samples. These curation efforts will result in the distribution of pristine Bennu samples from JSC to the OSIRIS‐REx science team, international partners, and the global scientific community for years to come.