Multiple heteroatom doping is identified as an effective method to realize superior anode materials for lithium-ion batteries (LIBs). In this study, a novel 4-fold interpenetrated dia MOF was ...synthesized and characterized and then used as a N,S-containing precursor to fabricate a foam-like CoO@N,S-codoped carbon hybrid composite via thermal treatment. In the composites, the outermost foam-like N,S-codoped carbon matrix can effectively buffer the drastic volume variations, enhance electronic conductivity, and prevent CoO nanoparticles from aggregation and pulverization during discharge/charge processes. Consequently, the novel hybrid nanomaterial exhibited excellent electrochemical properties as an anode material for LIBs. The specific capacity can retain a stable value of about 809 mA h g −1 at a current of 1000 mA g −1 within 500 cycles. As a proof-of-concept application, introduction of heteroatoms into MOFs can offer a valid method for doping the as-derived hybrid composites and then enhancing their performance as anodes of LIBs.
Porous N-doped carbon coated Co3O4 fish-scale structures were successfully fabricated via chemical transformation of a well-designed N-rich Co-MOF at 500 degree C in a nitrogen atmosphere. Due to the ...synergistic effect between the assembled porous Co3O4 nanoparticles and the N doped C coating, the sample exhibited excellent electrochemical properties as an anode material for lithium-ion batteries. The specific capacity can remain at a stable value of about 612 mA h g-1 at a current of 1000 mA g-1 within 500 cycles.
A new Cp*Rh(
iii
)-catalyzed regioselective cyclization reaction of aromatic amides with allenes is reported. The use of allenyl derivatives bearing a directing-group assistant as a reaction promoter ...was the key to the success of this protocol. In this catalytic system,
N
-(pivaloyloxy)benzamide substrates react with allenes
via
Rh-σ-alkenyl intermediates, while
N
-(pivaloyloxy) indol substrates react
via
Rh-π-allyl intermediates. These reactions were characterized by mild reaction conditions, a broad substrate scope, and high functional-group compatibility to yield several high-value isoquinolinone and pyrimido1,6-
a
indol-1(2
H
)-one skeleton-containing compounds. The synthetic applications and primary mechanisms were also investigated.
A mild reaction condition is employed for the Cp*Rh(
iii
)-catalyzed regioselective annulation of aromatic amides with allenes, enabling the preparation of isoquinolin-1(2
H
)-ones and pyrimido1,6-
a
indol-1(2
H
)-one.
Cancer cells acquire genetic heterogeneity to escape from immune surveillance during tumor evolution, but a systematic approach to distinguish driver from passenger mutations is lacking. Here we ...investigate the impact of different immune pressure on tumor clonal dynamics and immune evasion mechanism, by combining massive parallel sequencing of immune edited tumors and CRISPR library screens in syngeneic mouse tumor model and co-culture system. We find that the core microRNA (miRNA) biogenesis and targeting machinery maintains the sensitivity of cancer cells to PD-1-independent T cell-mediated cytotoxicity. Genetic inactivation of the machinery or re-introduction of ANKRD52 frequent patient mutations dampens the JAK-STAT-interferon-γ signaling and antigen presentation in cancer cells, largely by abolishing miR-155-targeted silencing of suppressor of cytokine signaling 1 (SOCS1). Expression of each miRNA machinery component strongly correlates with intratumoral T cell infiltration in nearly all human cancer types. Our data indicate that the evolutionarily conserved miRNA pathway can be exploited by cancer cells to escape from T cell-mediated elimination and immunotherapy.
The field of next‐generation microdisplays is flourishing. Relevant display technologies, such as mini‐light emission diodes (mini‐LEDs), micro‐organic light emission diodes (micro‐OLEDs), and ...micro‐light emission diodes (micro‐LEDs) are thus in the urgent stage of development. From this perspective, comprehensive and systematical analyzes are conducted for the aforesaid microdisplay configurations. A holistic view of microdisplay technologies is developed with the corresponding performance metrics, providing a path for miscellaneous scenarios. Among these scenarios, the applications in augmented reality (AR), virtual reality (VR), wearable devices, and head‐up displays (HUD) are currently attracting considerable attention for deeper human‐digital interactions. However, there is a multiplicity of obstacles and challenges hindering such development. Nevertheless, recent advances in microdisplay technologies hold tremendous promise for the paradigms of these applications, taking a leap forward for next‐generation microdisplays. This review presents perspectives, relevant materials, and the technology landscape for such ongoing display technologies, offering guidance on the design of advanced microdisplays.
The demand for augmented reality (AR), virtual reality (VR), wearables, and head‐up display (HUD) technology has fueled the rapid growth of next‐generation microdisplays. Despite their promise, challenges remain. This review analyzes performance metrics across various scenarios and provides valuable materials and technology perspectives for ongoing display technology. Our guidance for advanced microdisplay design aims to overcome obstacles and improve the field.
Edge computing technology can be used to the Internet of Vehicles (IOV) to solve the mobile characteristics of vehicles and the limited communication range between roadside units and vehicles. New ...method of edge computing-based data adaptive return in IOV is proposed in this article. The transmission strategy can be determined by adaptive estimating the vehicle movement, the amount of data returned, the maximum transmission delay, and effective life of link. And the factors, such as speed, direction, and position of the vehicles, are comprehensively considered and these factors can be measured by the stability effect value when adaptive designing the auxiliary transmission strategy. At the same time, greedy selection method is used when constructing the data return link, and the neighbor node as the relay node with the maximum stability and efficiency value is chosen. Our experimental results show our method in terms of performance on transmission delay and packet delivery rate is better than other ones.
RNA interference (RNAi) has been developed and used as an emerging strategy for pest management. Here, an entomopathogen
(
) was used to express the dsRNA for the control of
. A vector containing a ...325-bp fragment of the conserved region of
arginine kinase gene (
) flanking in two ends with the promoter Pro3α was developed and transferred into
8010 and BMB171, and consequently engineered
strains 8010AKi and BMB171AKi expressing dsRNA of
were developed. The two engineered
strains were separately mixed with
8010 in a series of ratios, and then fed to the
larvae. We found that 8010:8010AKi of 9:1 and 8010:BMB171AKi of 7:3 caused a higher mortality than
8010.
expression levels in the individuals treated with the mixtures, 8010AKi and BMB171Aki, were lower than that in the control. The intrinsic rate of increase (
) and net reproductive rate (
) of the population treated with 8010:8010AKi of 9:1 were lower than those of the population treated with
8010 or 8010AKi. We developed a
-mediated insect RNAi for the control of
and demonstrated a practical approach to integrating the entomopathogen with RNAi technique for the pest management.
Postsynthetic metalation (PSM) has been employed as a robust method for the postsynthetic modification of metal–organic frameworks (MOFs). However, the lack of relevant information that can be ...obtained for the postsynthetically introduced metallic ions has hindered the development of PSM applications. Thanks to the advancement in single-crystal X-ray diffraction (SCXRD) technology, there have been a few recent examples in which successful postsynthetic introduction of single metal ions into MOFs occurred at the defined chelating sites. These works have provided useful explanations about the complicated host–guest chemistry involved in PSMs. On the other hand, there are only limited examples with crystallographic snapshots of the postsynthetic installation of metal clusters into the pores of MOFs using an ordinary SCXRD due to the loss of crystallinity of parent matrix during the PSM process. Herein, by the careful selection of starting materials and controlling the reaction conditions, we report the first crystallographic visualization of metal clusters inserted into Zr-based MOFs via PSM. The structural advantages of the parent Zr-MOF, which are inherited from the stable Zr6 cluster and triazole-containing dicarboxylate ligand, ensure both the preservation of high crystallinity and the presence of flexible coordination sites for PSM. Furthermore, PSM of metal clusters in a MOF pore space enhances stability of the final samples while also imparting the functionality of a successful catalyst toward ethylene dimerization reaction. The related construction ideas and structural information detailed in this work can help lay the foundation for further advancements using the postmodification of MOFs as well as open new doors for the utilization of SCXRD technology in the field of MOFs.
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