Valsartan is an angiotensin receptor antagonist that specifically blocks the angiotensin II type 1 receptors. It is an effective and well-tolerated once-daily antihypertensive agent, with a ...tolerability profile similar to placebo. A recent series of large-scale clinical trials have shown the benefits of valsartan in disease states beyond hypertension. Based on the results of the Val-HeFT (Valsartan in Heart Failure Trial) and VALIANT (Valsartan in Acute Myocardial Infarction Trial) studies, valsartan is indicated for use in patients with heart failure and in patients post-myocardial infarction. Recently, in the VALUE (Valsartan Antihypertensive Long-term Use Evaluation) trial, valsartan was no more cardioprotective than calcium channel blockers, but was shown to reduce the risk of developing new-onset diabetes in hypertensive patients at high risk of cardiac events compared with calcium antagonist treatment. In diabetic patients with microalbuminuria, valsartan has been shown to have benefits beyond those attributable to blood pressure lowering alone.
We report the first evidence of charmless semileptonic decays of {ital B} mesons. In the momentum interval 2.4--2.6 GeV/{ital c} where the background from {ital b}{r arrow}{ital cl}{nu} is ...negligible, the average of the measured {ital b}{r arrow}{ital ue}{nu} and {ital b}{r arrow}{ital u}{mu}{nu} partial branching ratios is {Delta}{ital B}{sub {ital ub}}(2.4,2.6) =(1.8{plus minus}0.4{plus minus}0.3){times}10{sup {minus}4}. Inclusion of data from the interval 2.2--2.4 GeV/{ital c}, where the lepton yield is dominated by {ital b}{r arrow}{ital cl}{nu}, gives {Delta}{ital B}{sub {ital ub}}(2.2,2.6) =(3.3{plus minus}0.8{plus minus}0.8){times}10{sup {minus}4}. {vert bar}{ital V}{sub {ital ub}}/V{sub cb}{vert bar} depends on the theoretical model of {ital b}{r arrow}{ital ul}{nu} decay and is approximately 0.1.
Using the CLEO II detector, we have obtained evidence for a new meson decaying to ital Dsup 0ital Ksup +. Its mass is 2573.2sub minus1.6sup +1.7plus minus0.8plus minus0.5 MeV/ital csup 2 and its ...width is 16sub minus4sup +5plus minus3 MeV/ital csup 2. Although we do not establish its spin and parity, the new meson is consistent with predictions for an ital L=1, ital S=1, ital Jsup ital P=2sup + charmed strange state.
Luminosity measurement with the CLEO II detector
Nuclear instruments and methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment/Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
07/1994
Journal Article
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