Interstellar dust and starlight are modeled for the galaxies of the project "Key Insights on Nearby Galaxies: A Far-Infrared Survey with Herschel." The galaxies were observed by the Infrared Array ...Camera and the Multiband Imaging Photometer for Spitzer on Spitzer Space Telescope, and the Photodetector Array Camera and Spectrometer and the Spectral and Photometric Imaging Receiver on Herschel Space Observatory. With data from 3.6 to 500 m, dust models are strongly constrained. Using a physical dust model, for each pixel in each galaxy we estimate (1) dust surface density, (2) dust mass fraction in polycyclic aromatic hydrocarbons (PAHs), (3) distribution of starlight intensities heating the dust, (4) total infrared (IR) luminosity emitted by the dust, and (5) IR luminosity originating in subregions with high starlight intensity. The dust models successfully reproduce the observed global and resolved spectral energy distributions. With the angular resolution of Herschel, we obtain well-resolved maps (available online) for the dust properties. As in previous studies, we find the PAH fraction to be an increasing function of metallicity, with a threshold oxygen abundance Z/Z 0.1, but we find the data to be fitted best with increasing linearly with above a threshold value of 0.15(O/H) . We obtain total dust masses for each galaxy by summing the dust mass over the individual map pixels; these "resolved" dust masses are consistent with the masses inferred from a model fit to the global photometry. The global dust-to-gas ratios obtained from this study are found to correlate with galaxy metallicities. Systems with Z/Z 0.5 have most of their refractory elements locked up in dust, whereas in systems with Z/Z 0.3 most of these elements tend to remain in the gas phase. Within galaxies, we find that is suppressed in regions with unusually warm dust with . With knowledge of one long-wavelength flux density ratio (e.g., f160/f500), the minimum starlight intensity heating the dust ( ) can be estimated to within ∼50%, despite a variation in of more than two orders of magnitude. For the adopted dust model, dust masses can be estimated to within ∼0.2 dex accuracy using the f160/f500 flux ratio and the integrated dust luminosity, and to ∼0.07 dex accuracy using the 500 m luminosity alone. There are additional systematic errors arising from the choice of dust model, but these are hard to estimate. These calibrated prescriptions for estimating starlight heating intensity and dust mass may be useful for studies of high-redshift galaxies.
Political brokers mobilize voters all over the world, yet little is known about what motivates them to do so. This article theorizes about two drivers of brokers' efforts: (1) incentives—monetary ...rewards or sanctions—and monitoring and (2) partisan attachment. We examine our theory using data on the Mexican National Educational Workers Union (SNTE), Latin America's largest union and a well-known political machine. Consistent with the role of teachers as brokers, we find that the vote share of parties supported by the SNTE machine is higher in polling stations located in schools. This effect is absent when teachers are asked to mobilize voters in support of a party for which they have no partisan attachment, and it is uncorrelated with the union's monitoring capacity. This suggests that partisan attachment, rather than incentives and monitoring, explains the SNTE's effectiveness as a political machine.
The luminous Type IIn SN 2010jl shows strong signs of interaction between the SN ejecta and dense circumstellar material. Dust may be present in the unshocked ejecta; the cool, dense shell (CDS) ...between the shocks in the interaction region; or in the circumstellar medium (CSM). We present and model new optical and infrared photometry and spectroscopy of SN 2010jl from 82 to 1367 days since explosion. We evaluate the photometric and spectroscopic evolution using the radiative transfer codes mocassin and damocles, respectively. We propose an interaction scenario and investigate the resulting dust formation scenarios and dust masses. We find that SN 2010jl has been continuously forming dust based on the evolution of its infrared emission and optical spectra. There is evidence for preexisting dust in the CSM as well as new dust formation in the CDS and/or ejecta. We estimate that 0.005-0.01 M of predominantly carbon dust grains has formed in SN 2010jl by ∼1400 days post-outburst.
The triatomine
is the main vector of Chagas disease in countries such as Colombia and Venezuela, and the first kissing bug whose genome has been sequenced and assembled. In the repetitive genome ...fraction (repeatome) of this species, the transposable elements represented 19% of
genome, being mostly DNA transposon (Class II elements). However, scarce information has been published regarding another important repeated DNA fraction, the satellite DNA (satDNA), or satellitome. Here, we offer, for the first time, extended data about satellite DNA families in the
genome using bioinformatics pipeline based on low-coverage sequencing data. The satellitome of
represents 8% of the total genome and it is composed by 39 satDNA families, including four satDNA families that are shared with
, as well as telomeric (TTAGG)
and (GATA)
repeats, also present in the
genome. Only three of them exceed 1% of the genome. Chromosomal hybridization with these satDNA probes showed dispersed signals over the euchromatin of all chromosomes, both in autosomes and sex chromosomes. Moreover, clustering analysis revealed that most abundant satDNA families configured several superclusters, indicating that
satellitome is complex and that the four most abundant satDNA families are composed by different subfamilies. Additionally, transcription of satDNA families was analyzed in different tissues, showing that 33 out of 39 satDNA families are transcribed in four different patterns of expression across samples.
Background
ESG is a safe and effective technique in the obesity management, usually indicated in class I and II obesity. It is also an acceptable treatment in patients with class III obesity who have ...high surgical risk or refuse surgery. This procedure results in a significant weight loss and important improvement in metabolic comorbidities. Nevertheless, there are several procedure-related complications. Few cases of gastric perforation following ESG have been reported. We present a case of septic shock after ESG with preoperative diagnostic uncertainties.
Methods
We present the case of a 54-year-old male with a BMI of 43.6 kg/m2 who underwent ESG 7 days before in an external center. The patient came to the emergency department presenting abdominal pain, nausea, and vomiting since the day after the procedure. Physical examination revealed hemodynamic instability, altered level of consciousness, diffuse abdominal pain, and a painful umbilical lump due to a complicated umbilical hernia. Emergent surgery was decided after preoperative assessment.
Results
Intraoperative gastroscopy was performed, viewing a gastric ischemic ulcer covered with fibrin and a mucosal defect and suspecting a covered gastric perforation. Firstly, we performed an open approach to the complicated umbilical hernia. Subsequently, an exploratory laparoscopy was performed through the hernial ring, where a fibrin-covered area was evidenced in the anterior face of the gastric body, adhered to the round ligament by a transmural suture of the ESG. Additionally, multiple transmural sutures were observed adhered to the greater omentum and lesser sac and an intramural hematoma in the greater gastric curvature. No intra-abdominal free fluid was evidenced. A laparoscopic barbed suture of the area covered with fibrin was performed, after its release from the round ligament. The adhesions of the sutures and metallic material from the ESG were released. Finally, two abdominal drains were placed in the anterior and posterior gastric face. The patient presented superficial incisional surgical site infection and was discharged 6 days after laparoscopic surgery.
Conclusions
ESG is a novel procedure, which has proven to be an effective alternative in the treatment of obesity. However, this technique may have major complications that can require urgent surgery.
Most turtle species possess temperature-dependent sex determination (TSD), but genotypic sex determination (GSD) has evolved multiple times independently from the TSD ancestral condition. GSD in ...animals typically involves sex chromosomes, yet the sex chromosome system of only 9 out of 18 known GSD turtles has been characterized. Here, we combine comparative genome hybridization (CGH) and BAC clone fluorescent in situ hybridization (BAC FISH) to identify a macro-chromosome XX/XY system in the GSD wood turtle
Glyptemys insculpta
(GIN), the youngest known sex chromosomes in chelonians (8–20 My old). Comparative analyses show that GIN-X/Y is homologous to chromosome 4 of
Chrysemys picta
(CPI) painted turtles, chromosome 5 of
Gallus gallus
chicken, and thus to the X/Y sex chromosomes of
Siebenrockiella crassicollis
black marsh turtles. We tentatively assign the gene content of the mapped BACs from CPI chromosome 4 (CPI-4) to GIN-X/Y. Chromosomal rearrangements were detected in
G. insculpta
sex chromosome pair that co-localize with the male-specific region of GIN-Y and encompass a gene involved in sexual development (
Wt1
—a putative master gene in TSD turtles). Such inversions may have mediated the divergence of
G. insculpta
sex chromosome pair and facilitated GSD evolution in this turtle. Our results illuminate the structure, origin, and evolution of sex chromosomes in
G. insculpta
and reveal the first case of convergent co-option of an autosomal pair as sex chromosomes within chelonians.
We report far-infrared and submillimeter observations of supernova 1987A, the star whose explosion was observed on 23 February 1987 in the Large Magellanic Cloud, a galaxy located 160,000 light years ...away. The observations reveal the presence of a population of cold dust grains radiating with a temperature of about 17 to 23 kelvin at a rate of about 220 times the luminosity of the Sun. The intensity and spectral energy distribution of the emission suggest a dust mass of about 0.4 to 0.7 times the mass of the Sun. The radiation must originate from the supernova ejecta and requires the efficient precipitation of all refractory material into dust. Our observations imply that supernovae can produce the large dust masses detected in young galaxies at very high redshifts.
Objetivo Determinar el comportamiento temporal y espacial de la leptospirosis en México durante el periodo 2013-2019.Materiales y Métodos Se utilizó la información depositada en los boletines ...epidemiológicos del Sistema Nacional de Vigilancia Epidemiológica de México. Para determinar el comportamiento espacial se construyeron canales endémicos y análisis de series de tiempo. Para determinar el comportamiento espacial, se utilizó el modelo estadístico espacial Scan.Resultados Se determinó que los casos de leptospirosis en México se presentan todo el año; sin embargo, los picos endémicos se observaron en los meses de agosto, septiembre y octubre. Con respecto al comportamiento espacial, no se determinó ninguna agrupación estadísticamente; no obstante, los estados con la mayor prevalencia fueron: Sinaloa, con 146.7 casos por cada millón de habitantes, y Tabasco, con 142 casos por cada millón de habitantes.Discusión La leptospirosis es una enfermedad influenciada por los hábitos y las costumbres de la población, al igual que por variables climatológicas que favorecen el contacto con el agente etiológico. Esto coincide con lo reportado por otros estudios que han determinado que la incidencia de leptospirosis aumenta durante la época de lluvia y que esta enfermedad se relaciona con actividades de recreación en zonas tropicales.Conclusiones La leptospirosis es una enfermedad zoonótica emergente de gran importancia en México, que se presenta con mayor frecuencia en época de lluvias. Los estados de Sinaloa y Tabasco son los más afectados.
One of the biggest challenges of Higher Education is to train professionals prepared to join the workforce in a dynamic world, that can adapt rapidly to change and can acquire new knowledge and ...skills by themselves in this journey of lifelong learning. Our university recently implemented a New Educational Model having Challenge-Based Learning as one of its main pillars. The university collaborates with Educational Partners, which are companies, institutions or persons that open their doors to bring the students to a real-life environment to work on real challenges. This study shows a particular course of the fourth semester of the Biomedical Engineering curricula, that includes as its challenge to design a medical device from the ground up. The course was implemented in four different groups, with a slight twist in the allocated time to the theoretic modules and the challenge project, to study and determine the best theoretic/practice balance ratio. The course deliverables were analyzed to observe any significant differences in the students' progress and achievements along the course. A student perception survey was applied to understand the experiential learning involvement from their perspective. The results show that the shift in equilibrium towards the challenge project hours improves the outcomes results, and the change in time allocation does not have a significant impact in the overall students' scores and performance.
The W chromosome of Lepidoptera is typically gene-poor, repeat-rich and composed of heterochromatin. Pioneering studies investigating this chromosome reported an abundance of mobile elements. ...However, the actual composition of the W chromosome varies greatly between species, as repeatedly demonstrated by comparative genomic hybridization (CGH) or fluorescence in situ hybridization (FISH). Here we present an analysis of repeats on the W chromosome in the willow beauty, Peribatodes rhomboidaria (Geometridae), a species in which CGH predicted an abundance of W-enriched or W-specific sequences. Indeed, comparative analysis of male and female genomes using RepeatExplorer identified ten putative W chromosome-enriched repeats, most of which are LTR or LINE mobile elements. We analysed the two most abundant: PRW LINE-like and PRW Bel-Pao. The results of FISH mapping and bioinformatic analysis confirmed their enrichment on the W chromosome, supporting the hypothesis that mobile elements are the driving force of W chromosome differentiation in Lepidoptera. As the W chromosome is highly underrepresented in chromosome-level genome assemblies of Lepidoptera, this recently introduced approach, combining bioinformatic comparative genome analysis with molecular cytogenetics, provides an elegant tool for studying this elusive and rapidly evolving part of the genome.
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