We present the results of optical (R band) photometric and polarimetric monitoring and Very Long Baseline Array (VLBA) imaging of the blazar S5 0716+714 along with Fermi gamma -ray data during a ...multi-waveband outburst in 2011 October. We analyze total and polarized intensity images of the blazar obtained with the VLBA at 43 GHz during and after the outburst. Monotonic rotation of the linear polarization vector at a rate of > ~50degrees per night coincided with a sharp maximum in gamma -ray and optical flux. At the same time, within the uncertainties, a new superluminal knot appeared with an apparent speed of 21 + or - 2c. The general multi-frequency behavior of the outburst can be explained within the framework of a shock wave propagating along a helical path in the blazar's jet.
We use a combination of high-resolution very long baseline interferometry (VLBI) radio and multiwavelength flux density and polarization observations to constrain the physics of the dissipation ...mechanism powering the broadband flares in 3C 279 during an episode of extreme flaring activity in 2013-2014. Six bright flares superimposed on a long-term outburst are detected at γ-ray energies. Four of the flares have optical and radio counterparts. The two modes of flaring activity (faster flares sitting on top of a long-term outburst) present at radio, optical, and γ-ray frequencies are missing in X-rays. X-ray counterparts are only observed for two flares. The first three flares are accompanied by ejection of a new VLBI component (NC2), suggesting the 43 GHz VLBI core as the site of energy dissipation. Another new component, NC3, is ejected after the last three flares, which suggests that the emission is produced upstream from the core (closer to the black hole). The study therefore indicates multiple sites of energy dissipation in the source. An anticorrelation is detected between the optical percentage polarization (PP) and optical/γ-ray flux variations, while the PP has a positive correlation with optical/γ-ray spectral indices. Given that the mean polarization is inversely proportional to the number of cells in the emission region, the PP versus optical/γ-ray anticorrelation could be due to more active cells during the outburst than at other times. In addition to the turbulent component, our analysis suggests the presence of a combined turbulent and ordered magnetic field, with the ordered component transverse to the jet axis.
ABSTRACT
We present observations of SN 2020fqv, a Virgo-cluster type II core-collapse supernova (CCSN) with a high temporal resolution light curve from the Transiting Exoplanet Survey Satellite ...(TESS) covering the time of explosion; ultraviolet (UV) spectroscopy from the Hubble Space Telescope (HST) starting 3.3 d post-explosion; ground-based spectroscopic observations starting 1.1 d post-explosion; along with extensive photometric observations. Massive stars have complicated mass-loss histories leading up to their death as CCSNe, creating circumstellar medium (CSM) with which the SNe interact. Observations during the first few days post-explosion can provide important information about the mass-loss rate during the late stages of stellar evolution. Model fits to the quasi-bolometric light curve of SN 2020fqv reveal 0.23 M⊙ of CSM confined within 1450 R⊙ (1014 cm) from its progenitor star. Early spectra (<4 d post-explosion), both from HST and ground-based observatories, show emission features from high-ionization metal species from the outer, optically thin part of this CSM. We find that the CSM is consistent with an eruption caused by the injection of ∼5 × 1046 erg into the stellar envelope ∼300 d pre-explosion, potentially from a nuclear burning instability at the onset of oxygen burning. Light-curve fitting, nebular spectroscopy, and pre-explosion HST imaging consistently point to a red supergiant (RSG) progenitor with $M_{\rm ZAMS}\approx 13.5\!-\!15 \, \mathrm{M}_{\odot }$, typical for SN II progenitor stars. This finding demonstrates that a typical RSG, like the progenitor of SN 2020fqv, has a complicated mass-loss history immediately before core collapse.
As one of the most devastating forms of trauma, spinal cord injury (SCI) remains a challenging clinical problem. The secondary processes associated with the primary injury, such as overproduction of ...reactive oxygen species (ROS) and inflammation, lead to concomitant compression of the injured spinal cord and neuronal death. Delivery of copper-zinc superoxide dismutase (SOD1), an efficient ROS scavenger, to the site of injury can mitigate SCI-induced oxidative stress and tissue damage. Towards this goal catalytically active nanoformulations of SOD1 (“nanozymes”) are developed as a modality for treatment of SCI. Along with the cross-linked polyion complex of SOD1 with polycation poly(ethylene glycol) (PEG)-polylysine (single-coat (SC) nanozyme), we introduce for the first time the chemically cross-linked multilayer polyion complex in which SOD1 is first incorporated into a polyion complex with polycation, then coated by anionic block copolymer, PEG-polyglutamic acid (double-coat (DC) nanozyme). We developed DC nanozymes with high enzymatic activity and ability to retain and protect SOD1 under physiological conditions. Pharmacokinetic study revealed that DC nanozymes significantly prolonged circulation of active SOD1 in the blood stream compared to free SOD1 or SC nanozymes (half-life was 60 vs 6min). Single intravenous injection of DC nanozymes (5kU of SOD1/kg) improved the recovery of locomotor functions in rats with moderate SCI, along with reduction of swelling, concomitant compression of the spinal cord and formation of post-traumatic cysts. Thus, based on the testing in a rodent model the SOD1 DC nanozymes are promising modality for scavenging ROS, decreasing inflammation and edema, and improving recovery after SCI.
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Blazars are active galactic nuclei, which are powerful sources of radiation whose central engine is located in the core of the host galaxy. Blazar emission is dominated by non-thermal radiation from ...a jet that moves relativistically towards us, and therefore undergoes Doppler beaming. This beaming causes flux enhancement and contraction of the variability timescales, so that most blazars appear as luminous sources characterized by noticeable and fast changes in brightness at all frequencies. The mechanism that produces this unpredictable variability is under debate, but proposed mechanisms include injection, acceleration and cooling of particles, with possible intervention of shock waves or turbulence. Changes in the viewing angle of the observed emitting knots or jet regions have also been suggested as an explanation of flaring events and can also explain specific properties of blazar emission, such as intra-day variability, quasi-periodicity and the delay of radio flux variations relative to optical changes. Such a geometric interpretation, however, is not universally accepted because alternative explanations based on changes in physical conditions-such as the size and speed of the emitting zone, the magnetic field, the number of emitting particles and their energy distribution-can explain snapshots of the spectral behaviour of blazars in many cases. Here we report the results of optical-to-radio-wavelength monitoring of the blazar CTA 102 and show that the observed long-term trends of the flux and spectral variability are best explained by an inhomogeneous, curved jet that undergoes changes in orientation over time. We propose that magnetohydrodynamic instabilities or rotation of the twisted jet cause different jet regions to change their orientation and hence their relative Doppler factors. In particular, the extreme optical outburst of 2016-2017 (brightness increase of six magnitudes) occurred when the corresponding emitting region had a small viewing angle. The agreement between observations and theoretical predictions can be seen as further validation of the relativistic beaming theory.
Hybrid systems based on carbon nanotubes (CNTs) and fullerenes are promising for applications in nanoelectronics. Under small variations in the CNT diameter, the geometric characteristics of ...fullerenes change. Fullerenes regularly arranged inside a CNT present a set of quantum dots in a one-dimensional superlattice. By varying the fullerene concentration inside the nanotube and the fullerene types, it is possible to modulate the band structure of the CNT–fullerene system and control its electron and phonon characteristics. In this study, the optical and thermoelectric properties of properties of CNTs with encapsulated C
60
fullerene molecules are investigated. By the first-principles calculations, the absorption coefficients, optical conductivity, thermal conductivity, and thermoelectric quality factor are determined for a metal CNT with the fullerenes periodically arranged inside CNT at different distances from each other. It is established that, as the spacing between fullerenes is decreased, the optical conductivity of the CNT–C
60
system at high frequencies is suppressed. It is shown that the conductance of the structures with fullerenes is lower than the conductance of pure CNT and approximately the same for the spacing between fullerenes 12.3 and 19.7 Å. It is found that, due to the encapsulation of fullerenes, the thermal conductivity of the CNT becomes substantially lower (by a factor of three or four) for the CNT(8,8)–C
60
system.
In an effort to locate the sites of emission at different frequencies and physical processes causing variability in blazar jets, we have obtained high time-resolution observations of BL Lacertae over ...a wide wavelength range: with the Transiting Exoplanet Survey Satellite (TESS) at 6000-10000 with 2 minute cadence; with the Neil Gehrels Swift satellite at optical, UV, and X-ray bands; with the Nuclear Spectroscopic Telescope Array at hard X-ray bands; with the Fermi Large Area Telescope at γ-ray energies; and with the Whole Earth Blazar Telescope for measurement of the optical flux density and polarization. All light curves are correlated, with similar structure on timescales from hours to days. The shortest timescale of variability at optical frequencies observed with TESS is ∼0.5 hr. The most common timescale is 13 1 hr, comparable with the minimum timescale of X-ray variability, 14.5 hr. The multiwavelength variability properties cannot be explained by a change solely in the Doppler factor of the emitting plasma. The polarization behavior implies that there are both ordered and turbulent components to the magnetic field in the jet. Correlation analysis indicates that the X-ray variations lag behind the γ-ray and optical light curves by up to ∼0.4 day. The timescales of variability, cross-frequency lags, and polarization properties can be explained by turbulent plasma that is energized by a shock in the jet and subsequently loses energy to synchrotron and inverse Compton radiation in a magnetic field of strength ∼3 G.
Here we represent the first example of the formation of mixed nanoscale associates, constructed from amphiphilic calixresorcinarenes and hydrophobic carboxylic acids including drugs. The ...amidoamino-calixresorcinarene self-associates effectively solubilize hydrophobic carboxylic acids - drugs such as naproxen, ibuprofen, ursodeoxycholic acid and aliphatic dodecanoic acid - with the formation of the mixed aggregates with the macrocycle/substrate stoichiometry from 1/1 to 1/7. The ionization of organic acids and the peripheral nitrogen atoms of the macrocycles with the subsequent inclusion of hydrophobic acids into the macrocycle self-associates is the driving force of solubilization. In some cases, this leads to the co-assembly of the macrocycle polydisperse associates into supramolecular monodisperse nanoparticles with the diameter of about 100 nm. The efficiency of drug loading into the nanoparticles is up to 45% and depends on the structure of organic acid. The dissociation of the mixed aggregates and release of organic acid are attained by decreasing pH.
Blazars are active galactic nuclei (AGN) with relativistic jets whose non-thermal radiation is extremely variable on various timescales
. This variability seems mostly random, although some ...quasi-periodic oscillations (QPOs), implying systematic processes, have been reported in blazars and other AGN. QPOs with timescales of days or hours are especially rare
in AGN and their nature is highly debated, explained by emitting plasma moving helically inside the jet
, plasma instabilities
or orbital motion in an accretion disc
. Here we report results of intense optical and γ-ray flux monitoring of BL Lacertae (BL Lac) during a dramatic outburst in 2020 (ref.
). BL Lac, the prototype of a subclass of blazars
, is powered by a 1.7 × 10
M
(ref.
) black hole in an elliptical galaxy (distance = 313 megaparsecs (ref.
)). Our observations show QPOs of optical flux and linear polarization, and γ-ray flux, with cycles as short as approximately 13 h during the highest state of the outburst. The QPO properties match the expectations of current-driven kink instabilities
near a recollimation shock about 5 parsecs (pc) from the black hole in the wake of an apparent superluminal feature moving down the jet. Such a kink is apparent in a microwave Very Long Baseline Array (VLBA) image.
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