Several conditions as trauma, cancer surgical resection, fractures, congenital malformations and periodontitis could bring alveolar bone defects. To avoid more invasive and less predictable ...regenerative procedures, Stem cells of different origins as pluripotent Embryonic Stem Cells (ESCs), undifferentiated multipotent Mesenchymal Stem Cells (MSCs) and Induced Pluripotent Stem Cells (iPSCs) were proposed as possible alternative. IPSCs have potential for proliferation and differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm and mesoderm. According with their ability to involve in several cells type, Induced Pluripotent Stem Cells (iPSCs) could be proposed as alternative in regeneration either of mineralized tooth components or supporting tissue. The aim of this brief review is to describe clinical applications of Induced Pluripotent Stem Cells (iPSCs) in oral bone regeneration to employ their use in tissue regeneration in dentistry.
Aim: The objective of this paper was to show a case report of maxillary sinus lift with crestal access using the Magnetic Mallet technique and bio-material placement.
A new measurement of the cosmic-ray antiproton-to-proton flux ratio between 1 and 100 GeV is presented. The results were obtained with the PAMELA experiment, which was launched into low-Earth orbit ...on-board the Resurs-DK1 satellite on June 15th 2006. During 500 days of data collection a total of about 1000 antiprotons have been identified, including 100 above an energy of 20 GeV. The high-energy results are a tenfold improvement in statistics with respect to all previously published data. The data follow the trend expected from secondary production calculations and significantly constrain contributions from exotic sources, e.g., dark matter particle annihilations.
Objectives: over the years a device has been developed, the Magnetic Mallet, which allows a very high control and stability of the applied forces, able to perform procedures that were the safest ...possible for the patient and the surgeon himself. The handpiece has been designed so that different shock waves are emitted according to the type of surgery, with the possibility of inserting different inserts according to the technique/procedure that is being applied. The Magnetic Mallet can be used in different surgical procedures; Dental extractions, implant placement, implant site preparation (osseodensification), maxillary sinus lift procedures or crestal expansion procedures. Materials and methods: In the following clinical case, the extraction of element 2.7 is conducted with the simultaneous insertion of two implant fixtures in place 2.6 and 2.7 and simultaneous regenerative therapy. The implant in site 2.6 was positioned with a traditional method, with the help of the implant motor, while the post-extraction implant in site 2.7 was inserted with the use of the Magnetic Mallet. Results: At one week the sutures were removed and the tissues showed good healing. The patient is then placed in a maintenance and follow-up program to monitor healing after some time.
YODA++ is a proposal for a semi-automated data handling and analysis system for the PAMELA space experiment. The core of the routines have been developed to process a stream of raw data downlinked ...from the Resurs DK1 satellite (housing PAMELA) to the ground station in Moscow. Raw data consist of scientific data and are complemented by housekeeping information. Housekeeping information will be analyzed within a short time from download (1 h) in order to monitor the status of the experiment and to foreseen the mission acquisition planning. A prototype for the data visualization will run on an APACHE TOMCAT web application server, providing an off-line analysis tool using a browser and part of code for the system maintenance. Data retrieving development is in production phase, while a GUI interface for human friendly monitoring is on preliminary phase as well as a JavaServerPages/JavaServerFaces (JSP/JSF) web application facility. On a longer timescale (1–3 h from download) scientific data are analyzed. The data storage core will be a mix of CERNs ROOT files structure and MySQL as a relational database. YODA++ is currently being used in the integration and testing on ground of PAMELA data.
The fundamental moment of prosthetic rehabilitation is the "temporary". Although the meaning of the term diminishes its importance, the provisional has fundamental biological, aesthetic and ...functional functions. The oral cavity must maintain an adequate level of oral hygiene to carry out this delicate phase in the best possible way; a result achieved only with the collaboration of the prosthetic dentist with the hygienist and the patient, as if they were a biological system in motion. The different methods of hygiene are effective in maintaining a good level of oral health; but they could, if too aggressive, affect the prosthetic restoration. Our objective in vitro is to understand, after applying a known bacterial load, which hygiene method is the most effective in removing bacterial biofilm but at the same time is less aggressive towards resinous material.
The PAMELA Storage and Control Unit Casolino, M.; Altamura, F.; Basili, A. ...
Advances in space research,
2006, 2006-1-00, 20060101, Letnik:
37, Številka:
10
Journal Article
Recenzirano
Odprti dostop
The
PAMELA experiment aims to measure with great precision the antimatter present in our Galaxy in the form of high energy particles; in the same time it will measure the galactic, solar and trapped ...components of cosmic rays. The experiment will be housed on board a Russian Resurs-DK1 satellite and launched in the year 2005 to fly a 350–600 km orbit with an inclination of 70.4°. All operations of the instrument – including data storage – are handled by the
PAMELA Storage and Control Unit (PSCU), which is divided in a Central Processing Unit (CPU) and a Mass Memory (MM). The CPU of the experiment is based on a ERC-32 architecture (a SPARC v7 implementation) running a real time operating system (RTEMS). The main purpose of the CPU is to handle slow control, acquire and store data on a 2 GB MM. Communications between
PAMELA and the satellite are performed via a 1553B bus. Data acquisition from the sub-detectors (Time-of-Flight counter, Magnetic Spectrometer, Electromagnetic Calorimeter, Anticoincidence shield, Neutron Detector, and Bottom scintillator S4) is performed via a 2 MB/s interface. Download from the
PAMELA MM towards the satellite main storage unit is handled by a 16 MB/s bus. The daily amount of data transmitted to ground has been evaluated in not more 20 GB. In this work, we describe the CPU of the experiment and the general software scheme.
Objectives: The aim of this cross-sectional study was to describe QoL in a large sample of women attending menopause centres and compare untreated postmenopausal women and matched HRT users by ...employing the Women's Health Questionnaire (WHQ) and two generic instruments, the SF-36 and the EQ-5D.
Methods: Overall, 2906 women were recruited by 64 menopause centres throughout Italy, of whom 2160 filled in the questionnaire (1093 on HRT and 1067 not on HRT; response rate: 74%).
Results: HRT users tended to be younger, healthier and with shorter menopause duration as opposed to non users, while no major socio-economic differences were present. At multivariate analysis, the presence of chronic diseases, low socio-economic status and living in Southern Italy represented the most important predictors of poor QoL. Furthermore, HRT users showed a lower probability of reporting problems in usual activities and pain/discomfort (EQ-5D), role limitations due to emotional problems (SF-36) and anxiety/fears (WHQ). HRT users also showed highly significant better outcomes in those areas that are more directly attributable to hormonal changes of mid age, namely vasomotor symptoms and sexual problems.
Conclusions: Although QoL is mainly influenced by socio-economic and cultural factors, HRT has the potential for improving not only symptoms, but also more general aspects of physical and psychological well-being of symptomatic postmenopausal women.
Data processing and distribution in the PAMELA experiment Casolino, M.; Nagni, M.
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
03/2007, Letnik:
572, Številka:
1
Journal Article
Recenzirano
Odprti dostop
YODA is a semi-automated data handling and analysis system for the PAMELA space experiment. The core of the routines have been developed to process a stream of raw data downlinked from the Resurs DK1 ...satellite (housing PAMELA) to the ground station in Moscow. Raw data consist of scientific data and engineering information. Housekeeping information are analyzed in a short time from download
(
≃
hours
)
in order to monitor the status of the experiment and for the mission planning. A prototype for the data visualization runs on an APACHE TOMCAT web application server, providing an off-line analysis tool using a browser and part of code for the system maintenance. A quicklook system with GUI interface is used for operator monitoring and fast macrocommand issuing. On a longer timescale scientific data are analyzed, calibrations performed and the database adjourned. The data storage core is composed of CERN's ROOT files structure and MySQL as a relational database. YODA++ is currently being used in the integration and testing of ground PAMELA data.