As an acute effect, both ethanol and methanol prolong P-R, Q-T and ST intervals in rat electrocardiogram. The R wave amplitude showed a marked increase with methanol. Other ECG abnormalities like S-T ...segment changes, appearance of Iso-electric S-T segment, inverted 'T' wave, ventricular ectopic and wandering pace maker were more common in methanol treated animals.
Bone-derived Immunomodulator. An In-vitro Study SIVAPRAKASH, R. M. ANAND; DEVI, R. SHEELA; NAMASIVAYAM, A. ...
Pharmacy and Pharmacology Communications,
03/1997, Letnik:
3, Številka:
3
Journal Article
Recenzirano
The present study was designed to explore the role of bone marrow‐derived immuno‐modulators on the in‐vitro migration of splenocytes.
Leucocyte migration inhibition tests were carried out using ...different fractions of splenic cells against whole splenic cells, splenic cells after removal of macrophages and splenic cells after removing nylon wool‐adherent B cells from non‐sensitized and sensitized animals in the presence and absence of antigen.
Our results indicate that in the normal non‐sensitized splenic cell population, the bone marrow‐derived immunomodulators act on macrophages to enhance their migration. In the case of splenocytes derived from sensitized animals, the immunomodulators act not only on macrophages, but also on T cells.
Cassava (tapioca, manihot) is consumed as a staple food in some developing countries. The intake of cassava has been linked to several diseases including fibrocalculous pancreatic diabetes (tropical ...calcific pancreatitis). There are few long-term studies on the effect of cassava ingestion on the pancreas in animal models. This article reports on the long-term (up to 1 yr) effects of cassava in the rat model. We found that cassava did not produce diabetes in the rat even after a year of cassava feeding. There were transient changes in serum insulin and lipase levels, but the significance of these findings are not clear. There was no histopathological evidence of either acute or chronic pancreatitis, but there were changes of toxic hepatitis in the liver. In conclusion, chronic cassava ingestion up to a year does not lead to either diabetes or chronic pancreatitis in the rat model.
The binding of terreic acid to macromolecules such as nucleic acids and protein was examined. In vivo studies using 14Cterreic acid showed that radioactivity was incorporated into the protein and ...nucleic acid fractions of the liver mice. In vitro experiments with human serum showed that 14Cterreic acid bound to the albumin component and spectral studies indicated that terreic acid also combined with hepatic DNA.
Eastern Countries Singh, Sardar Bhagat; Shafqat, C. M.; Lahiri, S. M. ...
Journal of comparative legislation and international law,
01/1950, Letnik:
32, Številka:
1/2
Journal Article
Eastern Countries Gupta, S. K. D.; Rajagopalan, K. V.; Dhurandhar, J. R. ...
Journal of comparative legislation and international law,
01/1949, Letnik:
31, Številka:
1/2
Journal Article
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