Réduire en art Brioist, Pascal; Carvais, Robert; Castex, Jean-Gérald ...
2008
Book
Ce n'est que dans ces derniers siècles que les arts se sont vus, hors des laboratoires de l'ouvrier, faire l'occupation de la plume et des discours polis ... ils ont produit une si grande quantité de ...livres que la technologie est devenue un genre de littérature très considérable. La multitude de ses objets est immense par le nombre d'arts que le temps, le besoin et l'industrie ont mis au jour. Nicolas-Gabriel Clerc, 1789
Les manuscrits italiens du XVe siècle : maîtres à danser et traités de danse Les premiers écrits techniques sur la danse sont des manuscrits italiens du XVe siècle La production de traités est liée à ...un souci de normalisation qui émerge avec l’humanisme et vise à constituer un corpus de préceptes utiles à différents aspects de la vie individuelle et sociale. Si la danse fait l’objet de ce genre alors en développement pour d’autres arts et techniques, c’est grâce à la fonction que la société d...
Objectives
To explore the impact of sex and age on relationship between prodromal constipation and disease phenotype in Parkinson’s disease at early stages.
Methods
A total of 385 Parkinson’s disease ...patients from the PRIAMO study were classified according to the presence of prodromal constipation and followed for 24 months. Multivariable mixed-effect models were applied. All analyses were performed separately for sex (64.1% men) and median age (different by sex: 67 years-old in men and 68 years-old in women).
Results
As for sex, prodromal constipation was associated with greater odds of attention/memory complaints and apathy symptoms in women only. As for age, prodromal constipation was associated with lower cognitive and higher apathy scores in older patients only.
Conclusions
Prodromal constipation anticipates lower cognitive performances and more severe apathy since the earliest stages in women and older patients. Sex- and age-related heterogeneity of prodromal markers of Parkinson’s disease may impact disease phenotype.
The Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) has been available in English since 2008. As part of this process, the MDS-UPDRS ...organizing team developed guidelines for development of official non-English translations. We present here the formal process for completing officially approved non-English versions of the MDS-UPDRS and specifically focus on the first of these versions in Italian. The MDS-UPDRS was translated into Italian and tested in 377 native-Italian speaking PD patients. Confirmatory and exploratory factor analyses determined whether the factor structure for the English-language MDS-UPDRS could be confirmed in data collected using the Italian translation. To be designated an ‘Official MDS translation,’ the Comparative Fit Index (CFI) had to be ≥0.90 relative to the English-language version. For all four parts of the Italian MDS-UPDRS, the CFI, in comparison with the English-language data, was ≥0.94. Exploratory factor analyses revealed some differences between the two datasets, however these differences were considered to be within an acceptable range. The Italian version of the MDS-UPDRS reaches the criterion to be designated as an Official Translation and is now available for use. This protocol will serve as outline for further validation of this in multiple languages.
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