Personality Disorders O′Donohue, William T; Fowler, Katherine A; Lilienfeld, Scott O
2007, 2007-05-01
eBook
Personality Disorders: Toward the DSM-V offers a scientifically balanced evaluation of competing theoretical perspectives and nosological systems for personality disorders. Editors William T. ...O′Donohue, Scott O. Lilienfeld, and Katherine A. Fowler have brought together recognized authorities in the field to offer a synthesis of competing perspectives that provide readers with the richest and most nuanced assessment possible for each disorder. The result is a comprehensive, current, and critical summary of research and practice guidelines related to the personality disorders.
To characterize coronary blood flow velocity parameters and to determine the relation among velocity, volumetric flow, and vascular resistance in awake human beings, we performed paired proximal and ...distal velocity measurements in 28 angiographically normal coronary arteries. Mean velocity, peak velocity, diastolic-to-systolic velocity ratio, and diameter and cross-sectional area of proximal and distal arteries were determined and coronary flow and vascular resistance computed. Mean velocity and coronary vasodilator reserve were similar for all three native arteries and were preserved from proximal to distal segments. Volumetric flow decreased from proximal to distal segments. The demonstrated inverse and curvilinear (polynomial) relation between volumetric flow and vascular resistance agrees with theoretical and animal models of coronary physiologic characteristics and suggests a nadir of coronary vascular resistance below which coronary flow no longer increases.
Quantitation of coronary collateral flow in patients has been limited to angiographic techniques, which are subject to well-known methodologic limitations. The use of a Doppler-tipped angioplasty ...guidewire permits measurement of both antegrade and retrograde flow distal to totally or subtotally occluded vessels that may be supplied with acutely recruitable or angiographically mature collateral conduits. Using coronary flow velocity as an indicator of collateral flow, retrograde flow velocity was quantitated in 17 patients. Mean collateral flow velocity was approximately 30% of normal postangioplasty antegrade flow velocity. The phasic pattern of collateral flow was highly variable, but the retrograde diastolic and systolic flow velocity integrals were 20% and 40% (respectively) of post-procedure antegrade flow velocity. Preliminary studies with pharmacologic stimulation of the contralateral supply artery suggests that collateral flow is not increased by intracoronary nitroglycerin (200 micrograms) or adenosine (12 micrograms), but may be markedly augmented during mechanical stimulation of balloon occlusion. These data represent the first in a series of quantitative observations on control of the coronary collateral circulation in humans. Future investigations using the Doppler Flowire (Cardiometrics) will enhance understanding of factors modulating ischemia through collateral supply.
Previous studies have shown that deficiencies in selenium (Se) and/or vitamin E (VE) can exacerbate the infectivity and pathogenesis of coxsackievirus B3 and influenza. Both Se and VE play a role in ...immune function and antioxidant defense. To determine whether these deficiencies would affect the normal course of infection with a metazoan parasite, mice were made deficient in Se and/or VE and inoculated with the gastrointestinal nematode parasite Heligmosomoides polygyrus. Both primary and secondary infections were assessed. Although the course of a primary infection with H. polygyrus was unaffected by diet, diets deficient in Se, VE, and both Se and VE (Se/VE double-deficiency) all caused delayed adult worm expulsion and increased fecundity during a secondary infection; suggesting an impaired intestinal response. H. polygyrus-induced IL-4 levels were diet-independent; but Se/VE double-deficiency blocked the H. polygyrus-induced IL-4 receptor-associated decrease in sodium-dependent glucose absorption in the jejunum that contributes to worm expulsion. In contrast, Se/VE double-deficiency had no effect on the infection-induced, IL-4R-associated increase in epithelial cell permeability that accompanies the infection. These results suggest that both Se and VE are required for specific IL-4-related changes in intestinal physiology that promote host protection against H. polygyrus.
The effects of deficiencies in the antioxidant nutrients, vitamin E and selenium, on the host response to gastrointestinal nematode infection are unknown. The aim of the study was to determine the ...effect of antioxidant deficiencies on nematode-induced alterations in intestinal function in mice. BALB/c mice were fed control diets or diets deficient in selenium or vitamin E and the response to a secondary challenge inoculation with
Heligmosomoides polygyrus was determined. Egg and worm counts were assessed to determine host resistance. Sections of jejunum were mounted in Ussing chambers to measure changes in permeability, absorption, and secretion, or suspended in organ baths to determine smooth muscle contraction. Both selenium and vitamin E deficient diets reduced resistance to helminth infection. Vitamin E, but not selenium, deficiency prevented nematode-induced decreases in glucose absorption and hyper-contractility of smooth muscle. Thus, vitamin E status is an important factor in the physiological response to intestinal nematode infection and may contribute to antioxidant-dependent protective mechanisms in the small intestine.
Radionuclides. Their use in osteomyelitis Donohue, T W; Kanat, I O
Journal of the American Podiatric Medical Association,
06/1987, Letnik:
77, Številka:
6
Journal Article
Promoting Treatment Adherence provides health care providers with a comprehensive set of information and strategies for understanding and promoting treatment adherence across a wide range of ...treatment types and clinical populations. The information is presented in a practical how-to manner, and is intended as a resource that practitioners can draw from to improve skills in promoting treatment adherence.
I havent seen this disorder in ageswhats the latest treatment? What measures are most useful in assessing this problem?Her coverage allows so few visitscan we get anything done?Are there any ...useful self help materials or websites?How do I know this will work?Designed to bring ready answers from scientific data to real life practice, The Practitioners Guide to Evidence-Based Psychotherapy is an accessible, authoritative reference for todays clinician.The Guide, organized alphabetically for quick reference, distills vast amounts of proven knowledge and strategies (across the lifespan as well as across the DSM) into a user friendly, hands-on reference. Chapters are written by leading experts, focusing on appropriate assessment and empirically supported therapies. Here are solid guidelines for what to rule out, what works, what doesnt work and what can be improved for a wide range of mental health problems, including:- ADHD, learning disabilities, autism spectrum disorders- Bedwetting, feeding disorders, school refusal, thumb sucking- Bipolar disorder, obsessive-compulsive disorder, PTSD- Child abuse and domestic violence- Dysthymia, depression, suicidal thoughts- Erectile and orgasmic disorders- Smoking, gambling, substance abuse- Stress, chronic pain, insomniaDeveloped with the frontline clinicians time and cost constraints firmly in mind, the Practitioners Guide to Evidence-Based Psychotherapy allows readers to understand the best assessment and treatment options. This resource is designed to help clinical psychologists, clinical social workers, psychiatrists and counselors achieve the maximum in service to their clients. Concise and up-to-date, it also serves as an excellent student guide.Written for: Clinical psychologists, psychiatrists, clinical social workers, and counselors
A guide to working effectively with children in the criminal justice system Uniquely designed to train psychology, criminology, and social work students to work with children in the criminal justice ...system—both in the courtroom and as clinical clients—Forensic Child Psychology presents current research and practice-based knowledge to improve the judicial and child welfare systems. Authors Matthew Fanetti, William T. O'Donohue, Rachel N. Happel, and Kresta N. Daly bring their combined expertise in child psychology, forensic interviewing, and criminal prosecution to bear on the process of obtaining accurate information from children involved in legal proceedings, preparing professionals to work with: Children who are victims of crime Children who are perpetrators of crime Children who are witnesses of crime The book also covers related topics, including mandated reporting, the structure of juvenile justice and advocacy systems, and contains sidebars, summaries, glossaries, and study questions to assist with material mastery. This is an excellent resource for students of child psychopathology in psychology, social work, nursing, and criminal justice at the graduate and late undergraduate stage of their educations.
Understanding the Behavioral Healthcare Crisis is a necessary book, edited and contributed to by a great variety of authors from academia, government, and industry. The book takes a bold look at what ...reforms are needed in healthcare and provides specific recommendations. Some of the serious concerns about the healthcare system that Cummings, O'Donohue, and their contributors address include access problems, safety problems, costs problems, the uninsured, and problems with efficacy. When students, practitioners, researchers, and policy makers finish reading this book they will have not just a greater idea of what problems still exist in healthcare, but, more importantly, a clearer idea of how to tackle them and provide much-needed reform.
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