We have made a precise measurement of the absolute branching fractions of Bs->Ds(*)+ Ds(*)- decays using 121.4 fb-1 of data recorded by the Belle experiment running on the Upsilon(5S) resonance. The ...results are B(Bs0->Ds+ Ds-) = (0.58 +0.11 -0.09 +-0.13)%, B(Bs0->Ds*+- Ds-+) = (1.8 +-0.2 +-0.4)%, and B(Bs0->Ds*+ Ds*-) = (2.0 +-0.3 +-0.5)%; the sum is B(Bs0->Ds(*)+ Ds(*)- = (4.3 +-0.4 +-1.0)%. Assuming Bs->Ds(*)+ Ds(*)- saturates decays to CP-even final states, the branching fraction constrains the ratio Delta(Gamma_s)/cos(phi_s), where Delta(Gamma_s) is the difference in widths between the two Bs0-Bs0bar mass eigenstates, and phi_s is the CP-violating phase in Bs0-Bs0bar mixing. For phi_s=0 we obtain Delta(Gamma_s)/Gamma_s = 0.090 +-0.009 (stat.) +-0.023 (syst.), where Gamma_s is the mean decay width. We also measure for the first time the longitudinal polarization fraction of Bs->Ds*+ Ds*-; the result is 0.12 +0.30 -0.28 +0.04 -0.05.
The cross section for e^+e^- \to \eta J/\psi between \sqrt{s}=3.8 GeV/c^2 and 5.3 GeV/c^2 is measured via initial state radiation using 980 fb^{-1} of data on and around the \Upsilon(nS)(n=1,2,3,4,5) ...resonances collected with the Belle detector at KEKB. Two resonant structures at the \psi(4040) and \psi(4160) are observed in the \eta J/\psi invariant mass distribution. Fitting the mass spectrum with the coherent sum of two Breit-Wigner functions, one obtains BR(\psi(4040)\to\eta J/\psi)\cdot\Gamma_{ee}^{\psi(4040)} = (4.8\pm0.9\pm1.4) eV and BR(\psi(4160)\to\eta J/\psi)\cdot\Gamma_{ee}^{\psi(4160)} = (4.0\pm0.8\pm1.4) eV for one solution and BR(\psi(4040)\to\eta J/\psi)\cdot\Gamma_{ee}^{\psi(4040)} = (11.2\pm1.3\pm1.9) eV and BR(\psi(4160)\to\eta J/\psi)\cdot\Gamma_{ee}^{\psi(4160)} = (13.8\pm1.3\pm2.0) eV for the other solution, where the first errors are statistical and the second are systematic. This is the first measurement of this hadronic transition mode of these two states, and the partial widths to \eta J/\psi are found to be about 1 MeV. There is no evidence for the Y(4260), Y(4360), \psi(4415), or Y(4660) in the \eta J/\psi final state, and upper limits of their production rates in e^+e^- annihilation are determined.
Embryonal carcinoma is a model of embryonic development as well as tumor cell differentiation. In response to all-trans retinoic acid (RA), the human embryonal carcinoma (EC) cell line, NT2/D1, ...differentiates toward a neuronal lineage with associated loss of cell growth and tumorigenicity. Through the use of cDNA-based microarrays we sought to identify the early downstream targets of RA during differentiation commitment of NT2/D1 cells. A total of 57 genes were induced and 37 genes repressed by RA. RA regulated genes were restricted at 8 h with 27 genes induced and five repressed. The total number of RA-responsive transcripts increased at 24 and 48 h and their pattern of expression was more symmetrical. For a given time point less than 1% of the 9128 cDNAs on the expression array were regulated by RA. Many of these gene products are associated with developmental pathways including those of TGF- beta (Lefty A, NMA, follistatin), homeo domain (HoxD1, Meis2, Meis1, Gbx2), IGF (IGFBP3, IGFBP6, CTGF), Notch (manic fringe, ADAM11), Hedgehog (patched) and Wnt (Frat2, secreted frizzled-related protein 1) signaling. In addition a large cassette of genes induced by RA at 24-48 h are associated with cell adhesion, cytoskeletal and matrix remodeling, growth suppression and intracellular signaling cascades. The majority of repressed genes are associated with protein/RNA processing, turnover or metabolism. The early induced genes identified may play a regulatory role in RA-mediated growth suppression and terminal differentiation and may have physiologic or pharmacologic importance during normal human development and retinoid-based cancer therapy or prevention.
Radiohumeral stability to forced translation was experimentally analyzed in 8 osteocartilaginous joint preparations. The joints were dislocated in 8 centrifugal directions at 12 different ...combinations of joint flexion and rotation while a constant joint compression force of 23 N was applied. Stability was measured as the maximum resistance to translation. On average, the specimens could resist a transverse force of 16.4 N (range, 13.0-19.1 N). Stability was greater in some directions than in others. Rotating the joint changed the direction at which stability was greatest, whereas joint flexion did not. In supination, the greatest stability was observed for anteromedial dislocations, in neutral rotation for posteromedial dislocations, and in pronation for posterolateral dislocations. The findings from this study indicate systematic variations in wall height around the radial head concavity as well as individual variations in joint constraint. This may have implications for the treatment of conditions involving radiohumeral joint dislocation. (J Shoulder Elbow Surg 2002;11:158-165)
We present the second public data release of the Dark Energy Survey, DES DR2, based on optical/near-infrared imaging by the Dark Energy Camera mounted on the 4-m Blanco telescope at Cerro Tololo ...Inter-American Observatory in Chile. DES DR2 consists of reduced single-epoch and coadded images, a source catalog derived from coadded images, and associated data products assembled from 6 years of DES science operations. This release includes data from the DES wide-area survey covering ~5000 deg2 of the southern Galactic cap in five broad photometric bands, grizY. DES DR2 has a median delivered point-spread function full-width at half maximum of g= 1.11, r= 0.95, i= 0.88, z= 0.83, and Y= 0.90 arcsec photometric uniformity with a standard deviation of < 3 mmag with respect to Gaia DR2 G-band, a photometric accuracy of ~10 mmag, and a median internal astrometric precision of ~27 mas. The median coadded catalog depth for a 1.95 arcsec diameter aperture at S/N= 10 is g= 24.7, r= 24.4, i= 23.8, z= 23.1 and Y= 21.7 mag. DES DR2 includes ~691 million distinct astronomical objects detected in 10,169 coadded image tiles of size 0.534 deg2 produced from 76,217 single-epoch images. After a basic quality selection, benchmark galaxy and stellar samples contain 543 million and 145 million objects, respectively. These data are accessible through several interfaces, including interactive image visualization tools, web-based query clients, image cutout servers and Jupyter notebooks. DES DR2 constitutes the largest photometric data set to date at the achieved depth and photometric precision.
The inclusive production of D(s), D(0), and J/psi mesons is studied using a 1.86 fb(-1) data sample collected on the Upsilon(5S) resonance with the Belle detector at the KEKB asymmetric-energy ...e(+)e(-) collider. The number of bb events in this Upsilon(5S) data sample is determined. We measure the branching fractions B(Upsilon(5S)-->D(s)X)/2=(23.6+/-1.2+/-3.6)%, B(Upsilon(5S)-->D(0)X)/2=(53.8+/-2.0+/-3.4)%, and B(Upsilon(5S)-->J/psiX)/2=(1.030+/-0.080+/-0.067)%. From the D(s) and D(0) inclusive branching fractions the ratio f(s)=(18.0+/-1.3+/-3.2)% of B(s)(*)B(s)(*) to the total bb quark pair production at the Upsilon(5S) energy is obtained in a model-dependent way.
An epidemiologic and clinical study of traumatic vasospastic disease (TVD) was carried out involving 18 workers in a granite quarry. The prevalence of TVD was found to be 72 % (95 % confidence limits ...47—90 %) estimated from the combined information from a questionnaire and a clinical interview. The fingers of the hand contralateral to the preferred working hand were the most frequently affected. A newly developed cold provocation test measuring reduction in finger systolic blood pressure during combined body and finger cooling was applied to the quarrymen and to 20 age-matched men in a reference group. Raynaud's phenomenon with digital arterial closure was verified by the measurement of zero pressure in the test finger at 15 or 6°C in 12 of 13 quarrymen with anamnestic and clinical evidence of TVD. The test showed an abnormal response as compared to that of the reference group in all the workers having used vibrating hand tools for more than five years. The precision, estimated as 95 % confidence limits from double determinations, was 18.7 %. The cold provocation test can be employed diagnostically, and it can also be used to observe the effects of prophylactic measures.
The invariant mass spectrum of the \eta' \pi^+ \pi^- final state produced in two-photon collisions is obtained using a 673 fb^{-1} data sample collected in the vicinity of the \Upsilon(4S) resonance ...with the Belle detector at the KEKB asymmetric-energy e^+e^- collider. We observe a clear signal of the \eta_c and measure its mass and width to be M(\eta_c)=(2982.7 +- 1.8(stat) +- 2.2(syst) +- 0.3(model)) MeV/c^2 and \Gamma(\eta_c) = (37.8^{+5.8}_{-5.3}(stat) +- 2.8(syst) +- 1.4(model)) MeV/c^2. The third error is an uncertainty due to possible interference between the \eta_c and a non-resonant component. We also report the first evidence for \eta(1760) decay to \eta' \pi^+ \pi^-; we find two solutions for its parameters, depending on the inclusion or not of the X(1835), whose existence is of marginal significance in our data. From a fit to the mass spectrum using coherent X(1835) and \eta(1760) resonant amplitudes, we set a 90% confidence level upper limit on the product \Gamma_{\gamma\gamma} \BR (\eta' \pi^+ \pi^-) for the X(1835).
Based on a sample of 5.8×107J/ψ events taken with the BESII detector, the branching fractions of J/ψ→2(π+π−)η and J/ψ→3(π+π−)η are measured for the first time to be (2.26±0.08±0.27)×10−3 and ...(7.24±0.96±1.11)×10−4, respectively.