The association between mean arterial blood pressure (MAP) and hematocrit (Hct) as a surrogate for blood viscosity was investigated in a young (average 20.0±2.3 years), healthy population of 174 men ...and 442 women. Health status was assessed by clinical examination and serological evaluation. Individuals with severe anemia or hemoconcentration, prior traumas or major surgical intervention, smokers, and pregnant or lactating women were excluded from the study. The MAP/Hct association was positive and significant (P=0.04) for women and negative, albeit not significantly so, for men. The MAP/Hct association was also evaluated in subgroups of the same population with a progressive step-by-step exclusion of: individuals with cholesterol >200 mg/dL; triglycerides >200 mg/dL; body mass index >25 kg/m(2); and glucose >100 mg/dL. This consecutively reduced the strength of the positive MAP/Hct association in women, which became negative - although not significantly so - when all anomalously high factors were excluded. The same trend was found in men. Our study indicates that previously reported positive trends in the relationship between the MAP and Hct in the population are not present in a young, healthy population of men or women that excludes individuals with the confounding factors of above normal serological values and BMI.
Hispanic-Serving Institutions In American Higher Education Jesse Perez Mendez, Fred A. Bonner II, Josephine Méndez-Negrete, Robert T. Palmer / Jesse Perez Mendez, Fred A. Bonner II, Josephine Méndez-Negrete, Robert T. Palmer
2015, 2023-07-03, 2015-09-21
eBook
This is the first book to exclusively address Hispanic-serving institutions (HSIs), filling a major gap in the research on these institutions. Written by leading and rising scholars on HSIs, this ...book offers insight into the complexity of these institutions. It not only addresses historic policy origins, but also describes the experiences of various student populations served, examines faculty issues, addresses the role of student affairs in advancing student development, and considers issues of governance and funding. This book also critically examines the contradictions and challenges that many of these institutions face and looks to likely future developments.
Context. Extragalactic surveys are a key tool for better understanding the evolution of galaxies. Both deep and wide-field surveys serve to provide a clearer emerging picture of the physical ...processes that take place in and around galaxies, and to identify which of these processes are the most important in shaping the properties of galaxies. Aims. The Lockman Spectroscopic Redshift Survey using Osiris (Lockman-SpReSO) aims to provide one of the most complete optical spectroscopic follow-ups of the far-infrared (FIR) sources detected by the \textit{Herschel} Space Observatory in the Lockman Hole (LH) field. The optical spectroscopic study of the FIR-selected galaxies supplies valuable information about the relation between fundamental FIR and optical parameters, including extinction, star formation rate, and gas metallicity. In this article, we introduce and provide an in-depth description of the Lockman-SpReSO project and of its early results. Methods. We selected FIR sources from \textit{Herschel} observations of the central 24 arcmin \(\times\) 24 arcmin of the LH field with an optical counterpart up to 24.5 \(R_{\rm C}\)(AB). The sample comprises 956 \textit{Herschel} FIR sources, plus 188 additional interesting objects in the field. These are point X-ray sources, cataclysmic variable star candidates, high-velocity halo star candidates, radio sources, very red quasi-stellar objects, and optical counterparts of sub-millimetre galaxies. The faint component of the catalogue (\(R_{\rm C}(\mathrm{AB})\geq20\)) was observed using the OSIRIS instrument on the 10.4 m Gran Telescopio Canarias in multi-object spectroscopy (MOS) mode. The bright component was observed using two multi-fibre spectrographs: the AF2-WYFFOS at the William Herschel Telescope and the HYDRA instrument at the WYIN telescope.
The microtubule (MT) "plus end" constitutes the platform for the accumulation of a structurally and functionally diverse group of proteins, collectively called "MT plus-end tracking proteins" ...(+TIPs). +TIPs control MT dynamics and link MTs to diverse sub-cellular structures. Neurospora crassa MicroTubule Binding protein-3 (MTB-3) is the homolog of yeast EB1, a highly conserved +TIP. To address the function of MTB-3, we examined strains with mtb-3 deletions, and we tagged MTB-3 with GFP to assess its dynamic behavior. MTB-3-GFP was present as comet-like structures distributed more or less homogeneously within the hyphal cytoplasm, and moving mainly towards the apex at speeds up to 4x faster than the normal hyphal elongation rates. MTB-3-GFP comets were present in all developmental stages, but were most abundant in mature hyphae. MTB-3-GFP comets were observed moving in anterograde and retrograde direction along the hypha. Retrograde movement was also observed as originating from the apical dome. The integrity of the microtubular cytoskeleton affects the presence and dynamics of MTB-3-GFP comets, while actin does not seem to play a role. The size of MTB-3-GFP comets is affected by the absence of dynactin and conventional kinesin. We detected no obvious morphological phenotypes in DELTAmtb-3 mutants but there were fewer MTs in DELTAmtb-3, MTs were less bundled and less organized. Compared to WT, both MT polymerization and depolymerization rates were significantly decreased in DELTAmtb-3. In summary, the lack of MTB-3 affects overall growth and morphological phenotypes of N. crassa only slightly, but deletion of mtb-3 has strong effect on MT dynamics.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
The microtubule (MT) "plus end" constitutes the platform for the accumulation of a structurally and functionally diverse group of proteins, collectively called "MT plus-end tracking proteins" ...(+TIPs). +TIPs control MT dynamics and link MTs to diverse sub-cellular structures. Neurospora crassa MicroTubule Binding protein-3 (MTB-3) is the homolog of yeast EB1, a highly conserved +TIP. To address the function of MTB-3, we examined strains with mtb-3 deletions, and we tagged MTB-3 with GFP to assess its dynamic behavior. MTB-3-GFP was present as comet-like structures distributed more or less homogeneously within the hyphal cytoplasm, and moving mainly towards the apex at speeds up to 4 faster than the normal hyphal elongation rates. MTB-3-GFP comets were present in all developmental stages, but were most abundant in mature hyphae. MTB-3-GFP comets were observed moving in anterograde and retrograde direction along the hypha. Retrograde movement was also observed as originating from the apical dome. The integrity of the microtubular cytoskeleton affects the presence and dynamics of MTB-3-GFP comets, while actin does not seem to play a role. The size of MTB-3-GFP comets is affected by the absence of dynactin and conventional kinesin. We detected no obvious morphological phenotypes in Delta mtb-3 mutants but there were fewer MTs in Delta mtb-3, MTs were less bundled and less organized. Compared to WT, both MT polymerization and depolymerization rates were significantly decreased in Delta mtb-3. In summary, the lack of MTB-3 affects overall growth and morphological phenotypes of N. crassa only slightly, but deletion of mtb-3 has strong effect on MT dynamics.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
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•The g-C3N4@BiOBr heterojunction was hydrothermally synthesized at 130 °C.•The maximum visible light photoreactivity corresponds to a 1:2 M ratio.•The activity derives from the ...coupling of (002) g-C3N4 and (001) BiOBr surfaces.•The surfaces can degrade complex dye matrices and eliminate sulfadiazine.
A novel and versatile strategy to increase the photoreactivity (PR) of catalytic systems is to modulate the coupling between two dimensional (2D) semiconductors. Herein, a 2D heterojunction of graphitic carbon nitride (g-C3N4) and bismuth oxobromide (BiOBr), g-C3N4@BiOBr, was carefully synthesized by a solvothermal method at different molar ratios. The optical, morphological, structural, and electronic properties were characterized for the heterojunction and compared with pure 2D BiOBr and g-C3N4. The photocatalytic degradation kinetics of rhodamine B showed that the molar composition (1:2) of g-C3N4@BiOBr produces the largest activity under visible light. Radical scavenger studies showed that the (1:2) heterojunction in an oxygen-saturated environment induces superoxide and hole radicals that actively participate in the photodegradation, while the contribution of hydroxyl radicals is negligible. The optimized PR derives from the perfect coupling between (001) crystalline planes of BiOBr with (002) planes of g-C3N4as evidenced by HRTEM and XRD.To prove the photocatalytic efficiency, tests were carried out on the degradation of different dyes, their reuse cycles, and the degradation capacity of emerging contaminants, particularly for the antibiotic sulfadiazine, obtaining excellent promising results for the development of future commercial applications for the treatment of wastewater.
Triorganoindium reagents (R3In) react with tetrahydroisoquinolines (THIQs) in the presence of Ph3CBF4 as an oxidant to afford 1-substituted THIQs. The reaction proceeds in good yields at rt using 50 ...mol % R3In with a variety of organic groups. 1H NMR studies show the generation of an iminium ion intermediate, supporting a two-step mechanism based on THIQ oxidation and R3In nucleophilic addition. This reaction was applied to the synthesis of the alkaloid nuciferine in three steps.
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