The article presents solar modules of various types and designs, in the development and study of which the author took part. Along with planar photovoltaic solar modules with an extended term of ...nominal power, high-voltage matrix solar modules with an extended term of nominal power and electrical efficiency up to 28% are considered. Such modules are made with the help of encapsulation technology with a polysiloxane compound, which improves the performance of solar modules and increases their service life. For autonomous power supply of mobile and compact electrical devices in the field, folding and sectional solar modules are proposed, which, when parallel-sequential switching, allow to gain the necessary power. For architectural solutions, solar roofing panels are presented, which along with electrogeneration make it possible to generate heat energy, and the base can be made of recycled plastic, which has a positive effect on the environment. To reduce the number of solar cells used, a concentrating solar roofing panel has been proposed, which allows the use of thermal energy. For the cogeneration of electric energy and thermal energy, a concentrator solar photovoltaic thermal module with a paraboloid type concentrator is also proposed. Each type of solar modules is used in a stationary heat and electric power supply and mobile power generation.
The family of JADE proteins includes three paralogues encoded by individual genes and designated PHF17 (JADE1), PHF16 (JADE2), and PHF15 (JADE3). All three JADE proteins bear in tandem two Plant ...Homeo-domains (PHD) which are zinc finger domains. This review focuses on one member of the JADE family, JADE1. Studies addressing the biochemical, cellular and biological role of JADE1 are discussed. Recent discoveries of JADE1 function in the regulation of the epithelial cell cycle with potential relevance to disease are presented. Unresolved questions and future directions are formulated.
•PHD zinc finger proteins JADE1, JADE2, and JADE3 make up a small family of proteins.•JADE1 facilitates bulk histone H4 acetylation via interaction with an endogenous HAT.•JADE1S and JADE1L isoforms of JADE1 appear to play different cellular roles.•JADE1 proteins directly regulate cell cycle progression.•JADE1S is a negative regulator of cytokinesis and possibly the NoCut checkpoint.
Characteristics and special features of jet pumps with a curvilinear initial section of the mixing chamber are considered. The advantages of this type of pumps are noted in comparison with ...straight-jet pumps. The influence of the radius of curvature of the initial section of the mixing chamber on the jet pump characteristics is shown.
The Elegant sculpin
Bero elegans
is a plentiful but little-studied fish species that lives in the coastal shallow waters of the north-western part of the Japan Sea. In the study reported here, we ...assessed for the first time the life span, growth pattern, and age at maturity of this fish, based on growth and maturation observations and an analysis of the structure of otoliths from fish captured in Paris and Zhitkov bays, Russky Island, Peter the Great Bay, Sea of Japan in the period 2018–2022. The life span is estimated to be 47 months for females and 40 months for males. Males generally grow faster than females, but groups of slow-growing and fast-growing males that form during maturation are found. Both males and females spawn for the first time at 2 years of age. The von Bertalanffy’s growth function with three constants was used to calculate growth (
L
t
= estimated length as a function of time
t
months;
L
∞
= theoretical asymptotic length;
t
0
= theoretical time at 0 length;
k
= constant of linear growth), with the following values obtained:
L
∞
= 176.294,
k
= 0.033436,
t
0
= − 2.3394 at
R
= 0.95 for males;
L
∞
= 118.389,
k
= 0.0536,
t
0
= − 2.3464 at
R
= 0.94 for females (where
R
is otolith radius).
Nine years of ionograms from a higher mid-latitude ionospheric station (Moscow) are analyzed, by applying the ‘height–time–intensity’ (HTI) technique along with Spectrum (Lomb periodogram) analysis ...with the aim to investigate the daily and seasonal variability of sporadic E (Es) and intermediate descending layers (IDLs). Es and IDL traces are observed over Moscow, which are characterized by a 12-h periodicity prevailing throughout the year. Shorter periodicities in IDL and Es occurrence are also observed. A 6-h periodicity in Es and IDL dominates during November and December, while an 8-h periodicity is found mainly from October to February for IDL and in July for Es. These periodicities are primarily induced by the semi-, quarter- and terdiurnal thermospheric tides, respectively. Our results also establish the systematic and widespread manifestation of shorter-scale (4.8- and 4-h) periodicities observed mainly for IDL and less frequently for Es only during December and January, in the nine years considered, which is most probably linked to higher-order solar tides.
Graphical Abstract
Riboflavin (Rf) is a vitamin and endogenous photosensitizer capable to generate reactive oxygen species (ROS) under UV-blue irradiation and kill cancer cells, which are characterized by the enhanced ...uptake of Rf. We confirmed its phototoxicity on human breast adenocarcinoma cells SK-BR-3 preincubated with 30-μM Rf and irradiated with ultraviolet light, and proved that such Rf concentrations (60 μM) are attainable in vivo in tumour site by systemic intravascular injection. In order to extend the Rf photosensitization depth in cancer tissue to 6 mm in depth, we purpose-designed core/shell upconversion nanoparticles (UCNPs, NaYF
:Yb
:Tm
/NaYF
) capable to convert 2% of the deeply-penetrating excitation at 975 nm to ultraviolet-blue power. This power was expended to photosensitise Rf and kill SK-BR-3 cells preincubated with UCNPs and Rf, where the UCNP-Rf energy transfer was photon-mediated with ~14% Förster process contribution. SK-BR-3 xenograft regression in mice was observed for 50 days, following the Rf-UCNPs peritumoural injection and near-infrared light photodynamic treatment of the lesions.
Genetic heterogeneity of the population used in the experimental studies with living organisms as model objects is one of the reasons for the poor replicability of the results. Nonhuman primates ...represent the phylogenetically closest model to humans and it is possible to use it in the studies of genetic basis of diseases with a hereditary predisposition. However, primates represent a population that is significantly limited in number when kept in captivity. We have studied the genetic homogeneity of the population of male rhesus macaques by polymorphisms of genes
oprm1
,
npy
,
maoa
,
crh
, and
5-htt.
Cluster analysis (method of K-means) was used for the assessment considering data of genotyping, origination of the animals, blood count, and veterinary examination. Two significant clusters of animals were identified which differ in the values of blood count parameters within the reference range. The identified clusters are not associated with the origin, age, housing conditions, and the level of morbidity of animals. Clustering made it possible to identify a subpopulation of animals with frequency of carriers of
maoa
gene VNTR polymorphism with seven repeats 25% higher compared to the entire population. Thus, cluster analysis of nongenetic data may be of use to assess the homogeneity of the distribution of genetic variants in a population and to select a genetically more homogeneous subpopulation in order to reduce the problem of small samples in biomedical research.
Two intraspecific groups of the plain sculpin
Myoxocephalus jaok
inhabiting the Russian territoral waters in the Sea of Japan, representing the northern and southern species groups, have been ...revealed. In a summer season, the species groups are separated from each other by a wide water area extending from 45° to 48° N. The northern species-group nucleus in this period is located in the Tatar Strait inlet, while the southern species group inhabits the Peter the Great Bay. In the summertime, the plain sculpin prefers the upper slope shelf area with water column depths ranged from 80 m (for the southern species group) to 60 m (for the northern species group). The juvenile fish tend to be found in shallower waters as opposed to the mature fish. In a cold season, the majority of fish stocks of the southern species group is still congregating in the Peter the Great Bay, shifting to the shelf edge and the continental slope. Some porton of male fish remains at spawning grounds in the coastal zone to the springtime to guard egg clutches. The specimens of the nothern group leave the shallow-water Tatar Bay inlet at massive level to congregate over the winter in the locations of a deep-water area off the mid-coastal zone of the Sakhalin Island. The specimens of the northern group reach the body length of 67 cm, while the sizes in the southern fish group are larger, reaching 75 cm in length.
To analyze spontaneous behavior in 36 male rhesus macaques during formation of alcoholic motivation under free choice.
The model composed the initiation stage with the provision of an aqueous ethanol ...solution of increasing concentration from 1 to 4% with a sweetener and restricted access to the tap water supply and the subsequent stage of the formation of alcoholic motivation with a free choice between 4% ethanol solution without sweetener and water. The behavior was recorded by the «One-Zero» method with ethogram compiled in accordance with the behavioral peculiarities of rhesus monkeys when housed individually. Three subgroups of high, medium and low-level ethanol consumption were distinguished.
In the subgroup of high ethanol consumption median consumption was 1.70 g/kg/day at initiation (
0.05, compared to other subgroups) and 1.79 g/kg/day (
0.05) at free choice stage. Animals of high consumption subgroup had significantly higher frequency being at the cage bottom and in a sitting posture. We observed significant changes in a number of indicators of spontaneous behavior depending on the level of ethanol consumption, which included displacement behavior, stereotypic behavior and posture of animals. In the high consumption subgroup, there was a significant increase in the frequency of stereotypic behavior, atypical behavior, being on four legs, as well as a decrease in the frequency of being at the back side of the cage and of displacement behavior. At the same time, the inhibitory effect of ethanol on the hypothalamic-pituitary-adrenal system was revealed.
In the model of free choice alcohol self-administration rhesus monkeys demonstrate a significant change in a number of indicators of spontaneous behavior depending on the level of ethanol consumption, which includes displacement, stereotypic behaviors and animal posture.
—
It is shown that in Peter the Great Bay, the southern part of the range of the threaded sculpin
Gymnocanthus pistilliger
, its maximum size is larger than in the more northern waters off western ...Kamchatka
.
Reliable records of the species in trawl catches begin when individuals reach an absolute body length of 20 cm. Since males reach smaller sizes than females, their records, especially in the north, are less comprehensive. The growth rates of fish in Peter the Great Bay are higher, which is why the fish of the same age are larger here than in the waters off the Kamchatka Peninsula. The weight of individuals of the same size in the bay is also larger. The best growth rates in the area located to the south is determined by more favorable conditions of the aquatic environment. Despite the differences in growth rates, the maximum age of fish reached in populations is similar. The sex ratio with a predominance of females is also similar.
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