Rak tijela maternice, prema zadnjim podatcima Registra za rak iz 2017. godine u Republici Hrvatskoj, nalazi se na četvrtom mjestu po učestalosti, a na osmom mjestu po smrtnosti. Najčešće se ...dijagnosticira u postmenopauzalnih žena, većinom u dobi od 50. do 79. godine života. Dijagnoza karcinoma endometrija utvrđuje se patohistološkom analizom kiretmana ili bioptata sluznice maternice, a stupanj proširenosti bolesti primjenom slikovnih metoda. U većine bolesnica bolest se otkriva u lokaliziranom stadiju te se uspješno liječi operativno, a ovisno o patohistološkom nalazu i primjenom odgovarajuće adjuvantne terapije. Lokalno uznapredovala bolest najčešće se liječi operativno uz adjuvantnu terapiju, a metastatska primjenom kemoterapije ili hormonske terapije. Mezenhimalni tumori tijela maternice liječe se operativno uz dodatak sistemske terapije adjuvantno ili samo sistemskom terapijom u slučaju diseminirane bolesti. Ove kliničke upute pisane su u cilju postizanja najviših standarda i ujednačenja postupaka u dijagnosticiranju, liječenju i praćenju bolesnica sa zloćudnim tumorima tijela maternice u Republici Hrvatskoj.
Rak vrata maternice, u odnosu na novotvorine drugih ginekoloških sijela, bolest je žena mlađe životne dobi koja se može prevenirati zdravstvenim odgojem i cijepljenjem adolescentske populacije te ...preventivnim i redovitim ginekološkim pregledima, a u ranim stadijima bolesti i učinkovito liječiti. Metode liječenja uključuju kirurgiju, radioterapiju i sistemnu terapiju, ovisno o stadiju bolesti i općem stanju bolesnica. Odluku o liječenju donosi multidisciplinarni tim u koji trebaju biti uključeni ginekolozi, radiolozi, klinički onkolozi, patolozi, citolozi i po potrebi kirurzi i urolozi. Uspjeh liječenja uvelike ovisi o njihovoj međusobnoj suradnji i kvalitetnoj komunikaciji u razmjeni iskustava i nalaza. S obzirom na važnost ove bolesti i posljedice koje ostavlja na obitelj i društvo potrebno je definirati i provoditi standardizirani pristup u dijagnostici, liječenju i praćenju ovih bolesnica. U tekstu koji slijedi iznesene su obnovljene i nadopunjene kliničke smjernice s ciljem implementacije standardiziranih postupaka u radu s bolesnicama s rakom vrata maternice u Republici Hrvatskoj.
Uterine choriocarcinoma - a case report Paradžik-Pašalić, Vanda; Lešin, Joško; Matković, Višnja ...
Libri oncologici,
05/2021, Letnik:
49, Številka:
1
Journal Article
Recenzirano
Odprti dostop
Choriocarcinoma is one of the histological types of entities called gestational trophoblastic neoplasia (GTN) that refers to a rare group of malignancies that are formed by abnormal proliferation of ...trophoblastic tissue. Choriocarcinoma is the most aggressive GTN histological type and is characterized by early vascular invasion and disseminated disease. The clinical presentation depends on the spread of the disease and the location of the seedlings. In this paper we present the case of a 32-year-old patient sent to our Department for a specific oncological treatment of uterine choriocarcinoma diagnosed in an external institution. The disease is according to FIGO and WHO scale classified as III stage, low risk and chemotherapy with methotrexate and folic acid is indicated. The chemotherapy achieved negativity of the initially elevated tumor marker human chorionic gonadotropin (hCG) and full regression of lesions described in computerized tomography (CT).
Uterine cancer, according to the latest data from the 2017 Croatian Cancer Registry, is the fourth most common cancer in women in Croatia and ranking eighth in mortality. Most commonly, it is ...diagnosed in postmenopausal women at the age 50–79. Endometrial cancer diagnosis is determined by pathohistological analysis of curettage or biopsy and the stage of the disease by radiological imaging. In most patients, the disease is diagnosed in the localized stage and is successfully treated surgically; depending on the pathohistological finding, appropriate adjuvant therapy could be applied. Locally advanced disease is most commonly treated surgically with adjuvant therapy, and metastatic with chemotherapy or hormone therapy. Mesenchymal tumors of the uterine body are treated surgically with the addition of systemic adjuvant therapy, or only systemic therapy in the case of metastatic disease. The following manuscript presents clinical guidelines to standardise procedures for the diagnosis, treatment and follow-up of patients with malignant tumors of the uterus in the Republic of Croatia.
Cervical cancer, in comparison with other gynecological malignancies, mainly affects younger women. It can be prevented through educational programs, vaccination, screening and early detection. In ...early stages it can also be effectively treated. Treatment modalities include surgery, radiotherapy and systemic therapy according to stage of the disease and patient condition. Treatment decisions should be made through multidisciplinary team meetings that consist of gynecologists, radiologists, clinical oncologists, pathologists, cytologists and if necessary surgeons and urologists. The success rate of the treatment depends significantly on their good and thorough communication and cooperation. Due to the significance and impact of this disease it is important to define and implement a standardized algorithm and approach for diagnostics, treatment and monitoring. The following text presents up-dated and supplemented clinical guidelines for the standardization of the diagnostic criteria, management, treatment and monitoring of patients with uterine cervical cancer in the Republic of Croatia.
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