Inclusions of benign tissues in lymph nodes are most often aberrant glandular tissue, including endosalpingiosis, the thyroid, parotid, breast, and pancreas. Nonglandular inclusions are rare and ...include nevus cells and decidua. Mesothelial cells in lymph nodes are exceedingly rare; only eight cases have been reported in mediastinal lymph nodes and three cases in abdominal lymph nodes. The incidence of benign mesothelial cells in mediastinal lymph nodes in patients with a history of pericarditis or pleuritis is reported in this study. A retrospective search showed eight cases with removal of mediastinal lymph nodes in the absence of neoplasm. Hematoxylin and eosin-stained sections were examined in all cases. Immunohistochemical stains for CAM 5.2 were performed in all cases, and stains for AE1/AE3, Ber-EP4, carcinoembryonic antigen, Leu-M1, B72.3, and S-100 were performed in one case. CAM 5.2-positive cells with features of mesothelial cells were present in five of eight cases. In all cases, the cells were present in nodal sinuses and appeared as single cells or small clusters. The cells were missed on routine hematoxylin and eosin sections in all cases but one, in which they were numerous and mimicked metastatic carcinoma. Malignancy was not found in any of the cases preoperatively, at the time of surgery, or during the follow-up period. Benign mesothelial cells may embolize to regional lymph nodes in pleuritis or pericarditis. In most cases, these cells are few and undetectable on routine sections. Rarely, hyperplastic mesothelial cells may be present and must be distinguished from metastatic carcinoma, mesothelioma, and melanoma.
Objectives: Amniotic fluid levels of nitric oxide metabolites are significantly elevated in intra-amniotic infection. We hypothesized that fetal amnion is a possible site for the production of nitric ...oxide. Because inducible nitric oxide synthase is the key enzyme responsible for the generation of nitric oxide in patients with intra-amniotic infection, we used immunohistochemistry to localize it on human fetal amnion.
Study Design: Human fetal amnions were obtained from patients with and without intra-amniotic infection (
n = 5, respectively). Intra-amniotic infection was diagnosed by positive amniotic fluid cultures and placental pathologic features. Human fetal amniotic membranes were processed into tissue blocks and embedded in paraffin. A rabbit polyclonal antibody against human inducible nitric oxide synthase was used as the primary antibody, followed by avidin-biotin immunoperoxidase localization. Normal rabbit serum was used as a negative control and ovarian carcinoma cells were used as the positive control.
Results: Anti–inducible nitric oxide synthase labeling of human fetal amniotic membranes in patients with intra-amniotic infection showed positive immunostaining of epithelial cells, specifically in the cytoplasm of the perinuclear area. In contrast, no anti–inducible nitric oxide synthase immunostaining on human fetal amniotic membranes could be identified in patients without intra-amniotic infection.
Conclusions: Our data provide important evidence that inducible nitric oxide synthase can be induced on human fetal amnion in intra-amniotic infection. These findings strongly support our hypothesis that human fetal amnion may be a possible site for the synthesis of nitric oxide after inducible nitric oxide synthase is induced in response to infectious products in intra-amniotic infection. (Am J Obstet Gynecol 1998;179:1271-4.)
Identification of two imidazole binding sites in VAP-1 Bligt, E.; Parkash, V.; Nymalm-Rejström, Y. ...
Acta crystallographica. Section A, Foundations of crystallography,
08/2011, Letnik:
67, Številka:
a1
Journal Article
We report a patient who developed metastatic gestational choriocarcinoma following delivery of a normal, healthy child that, however, was anemic and required blood transfusion. The patient developed ...secondary postpartum hemorrhage over a period of several weeks and required curettage and myometrial contractants to control the bleeding. At the time of diagnosis the patient had extensive pulmonary metastases and ultrasound showed full penetration of the myometrium by tumor. Immediately following the second course of chemotherapy with etoposide, methotrexate, and actinomycin D, alternating with cyclophosphamide and vincristine, the patient developed sepsis associated with a uteroperitoneal fistula and required hysterectomy. The sepsis was associated with disseminated intravascular coagulopathy and adult respiratory distress syndrome. However, the patient's tumor was exquisitely sensitive to chemotherapy and with good intensive care unit support and chemotherapy she survived without residual scar except for the loss of reproductive function. There are two lessons to be learned from these events: (1) The syndrome of secondary postpartum hemorrhage with a fetus that is anemic spells a diagnosis of choriocarcinoma; and (2) color Doppler flow vaginal ultrasound performed at the time of presentation of trophoblastic tumors may be useful to show full penetration of the myometrium by tumor which may be a warning of possible scar rupture in a subsequent pregnancy.
Seven species of
,
and
) from sunflower rhizosphere are described and illustrated. A key to species of the genus
is also prepared based on morphological characters. Spores of these species were ...identified on the basis of their morphological characters such as hyphal attachment, spore ornamentation, wall layers and spore color and size.
Se describieron e ilustraron siete especies de
,
y
de la rizósfera del girasol. Además se preparó una clave de las especies del género
sobre la base de caracteres morfológicos. Se identificaron esporas de esas especies de acuerdo con características morfológicas como adherencia hifal, ornamentación de las esporas, capas de las paredes y color y tamaño de las esporas.
Sept espèces du genre
et
) de la rhizosphère du tournesol sont décrites et illustrées. Une clef de détermination de l’espèce au sein du genre
est préparée sur la base des caractères morphologiques. Les spores de ces espèces ont été identifiées sur des caractères morphologiques tels que l’attachement des hyphes, l’ornementation des spores, la paroi, la couleur et la taille des spores.
Carbon nanotubes are promising candidates for futuristic nanoelectronic applications due to their excellent properties. In this paper, we present a comprehensive modeling and calculation of ...electrostatic capacitances for various carbon nanotube systems that can be used to model interconnects in nanotechnology circuits. We provide results for single walled, multiwalled and bundles of single-walled carbon nanotubes as functions of the various design parameters. Numerical computations were performed using the method of moments in conjunction with a Greenpsilas function appropriate for the geometry of the interconnects.
Superficial acral fibromyxoma is an uncommon benign tumour which was first described recently (Fetsch et al., 2001, Human Pathology 32: 704–714). It has been reported several times since, suggesting ...it is more common than initially thought.
A total of seven
species (
) isolated from sunflower rhizosphere are described and illustrated. A key to species of
genus has also been prepared on the basis of their morphological characters. Spores ...of these species have been identified by morphological characters such as hyphal attachment if any, spore ornamentation, wall layers and spore color and size.
Se describieron e ilustraron siete especies de
) aisladas de la rizósfera del girasol. Se preparó una clave de las especies del género
sobre la base de caracteres morfológicos. Se identificaron las esporas de estas especies sobre la base de caracteres morfológicos como adherencia hifal si la hubiera, ornamentación de las esporas, capas de las paredes celulares y color y tamaño de esporas.
Un total de sept espèces du genre
) isolées à partir de la rhizosphère du tournesol sont décrites et illustrées. Une clef de détermination de l’espèce au sein du genre
est préparée sur la base des caractères morphologiques. Les spores de ces espèces ont été identifiées sur des caractères morphologiques tels que l’attachement des hyphes le cas échant, l’ornementation des spores, la paroi, la couleur et la taille des spores.
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