La théorie de l’action situationnelle (TAS) est une théorie générale du crime qui
propose d’expliquer la décision du passage à l’acte délinquant comme le résultat de
l’interaction entre la propension ...criminelle d’un individu et l’environnement criminogène
dans lequel cet individu décide de commettre un délit. Sur la base de l’échantillon des
données belges de la Recherche Internationale de Délinquance Auto-révélée (ISRD-3), composé
de 4758 adolescents, des régressions multiples (OLS) ont été menées afin de tester les
questions centrales de l’axe situationnel ainsi que quelques questions de l’axe
sociodéveloppemental. Les résultats obtenus démontrent que la propension criminelle et
l’exposition à des environnements criminogènes participent individuellement et conjointement
au comportement délinquant des adolescents ; que la moralité explique davantage cette
propension criminelle que le contrôle de soi ; et enfin, que cette propension est elle-même
expliquée de façon significative par de faibles relations avec les parents et avec l’école
ainsi que par une criminalité perçue à l’école et dans le voisinage (exposition
socioécologique). Les contributions de cette recherche tendent à confirmer les questions
centrales de la TAS auprès d’un échantillon européen, en partie francophone, nous permettant
de discuter certaines pistes de prévention et défis méthodologiques autour de la
TAS.
Gastrointestinal stromal tumours (GIST) are mesenchymal tumours which mostly arise in the gastrointestinal tract showing positive CD117 immunohistochemical staining. In recent years, other locations ...such as the mesentery and the retroperitoneum have been reported.
A 77-year-old woman presented with a pelvic mass, raising the suspicion of an ovarian or a uterine tumour. During laparotomy, a ruptured process arising from the uterus was seen and removed. Histologic features, immunophenotype and genotype of the tumour supported the diagnosis of a GIST.
To the best of our knowledge, this is the first case of a primary GIST presenting as a uterine mass. Because of recent advances in GIST-therapy, making a correct diagnosis has major clinical implications.
Summary
Neurectomy of the deep branch of the right lateral plantar nerve was performed on a single healthy mature horse. Six weeks after surgery, the horse was subjected to euthanasia and both hind ...suspensory ligaments harvested. The cross sectional area of the muscular part of the proximal part of the suspensory ligament was measured and assessed for morphological abnormalities in a blinded fashion. There was a clear difference in cross sectional area of the muscular part between treated and control ligament and there was profound neurogenic atrophy of the muscular fibres in the treated ligament.
Summary
Ten new crystal structures of cis and trans bicyclic diketopiperazines (DKPs) of thia‐pipecolic acid (with sulfur in the β, γ or δ position) or thia‐proline (with sulfur in the β or γ position) and ...N‐methyl phenylalanine (NMe)Phe: cyclo(β‐S)Pip‐(NMe)Phe, cyclo(γ‐S)Pip‐(NMe)Phe, cyclo(δ‐S)Pip‐(NMe)Phe, cyclo(β‐S)Pro‐(NMe)Phe and cyclo(γ‐S)Pro‐(NMe)Phe were determined with X‐ray crystallography. Density functional theory calculations of these molecules in the gas phase succeed in reproducing the observed molecular conformations in the crystal remarkably well. This illustrates the weak to moderate impact of intermolecular packing forces in the absence of classical N—H…O hydrogen bonds. The effect of sulfur on the geometry of the DKP ring and details of amide bond non‐planarity are discussed. Molecular flexibility of the DKP ring, as estimated from the calculated deformation energies of its endocyclic ring torsion angles, is not in general the decisive factor for the occurrence of multiple symmetry independent molecules in the unit cell (Z′ > 1), though in some cases a correlation is observed.
X‐ray and computational study of cis‐ and trans‐diketopiperazines of N‐methyl‐phenylalanine with the thia‐pipecolic acids and thia‐prolines are presented. The effect of sulfur on the geometry of diketopiperazine ring and amide bond non‐planarity is discussed.
Recent studies reported significant additional clinical and microbiological improvements when severe adult periodontitis was treated by means of a "one-stage full-mouth" disinfection instead of a ...standard treatment strategy with consecutive root planings quadrant per quadrant. The one stage full-mouth disinfection procedure involves scaling and root planing of all pockets within 24 h in combination with an extensive application of chlorhexidine to all intra-oral niches such as periodontal pockets, tongue dorsum, tonsils (chairside, and at home for 2 months). This study aims to examine the relative importance of the use of chlorhexidine in the one stage full-mouth disinfection protocol.
Therefore, 3 groups of 12 patients each with advanced periodontitis were followed, both from a clinical and microbiological point of view, over a period of 8 months. The patients from the control group were scaled and root planed, quadrant per quadrant. at two-week intervals. The 2 other groups underwent a one stage full-mouth scaling and root planing (all pockets within 24 h) with (Fdis) or without (FRp=full-mouth root planing) the adjunctive use of chlorhexidine. At baseline and after 1, 2, 4 and 8 months, the following clinical parameters were recorded: plaque and gingivitis indices, probing depth, bleeding on probing and clinical attachment level. Microbiological samples were taken from different intra-oral niches (tongue, mucosa, saliva and pooled samples from single- and multi-rooted teeth). The samples were cultured on selective and non-selective media in order to evaluate the number of CFU/ml for the key-periodontopathogens. At baseline, an anonymous questionnaire was given to the patients to record the perception of each treatment (post operative pain, fever, swelling etc.).
All 3 treatment strategies resulted in significant improvements for all clinical parameters, but the Fdis and FRp patients reacted always significantly more favourably than the control group, with an additional probing depth reduction of +/- 1.5 mm and an additional gain in attachment of +/- 2 mm (for pockets > or = 7 mm). Also from a microbiological point of view both the FRp and Fdis patients showed additional improvements when compared to the control group, as well in the reduction of spirochetes and motile organisms as in the number of CFU/ml of the key-pathogens, especially when the subgingival plaque samples were considered. The differences between FRp and Fdis patients were negligible.
These findings suggest that the benefits of a "one-stage full-mouth disinfection" in the treatment of patients suffering from severe adult periodontitis probably results from the full-mouth scaling and root planing within 24 h rather than the beneficial effect of chlorhexidine. The raise in body temperature the second day after the full-mouth scaling and root planing seems to indicate a Shwartzman reaction.
Gaia Data Release 2 Bastian, U.; Babusiaux, C.; Breddels, M. A. ...
Astronomy and Astrophysics - A&A,
05/2020, Letnik:
637
Journal Article, Publication
Recenzirano
Odprti dostop
An error occurred during the production process of the original published version. The following names were omitted from theauthor list: R. Haigron, D. Hatzidimitriou, M. Hauser, M. Haywood, U. ...Heiter, J. Heu, T. Hilger. The original published version hasbeen corrected together with the publication of this corrigendum.