A 10-center randomized prospective multicenter study of endoscopic release of the carpal tunnel was carried out. Surgery was performed with a new device for transecting the transverse carpal ligament ...while control hands were treated with conventional open surgery. There were 122 patients in the study; 25 had carpal tunnel surgery on both hands and 97 had surgery on one hand. Of the surgical procedures, 65 were in the control group and 82 were in the device group. The endoscopic device was coupled to a fiberoptic light and a video camera. A trigger-activated blade was used to incise the transverse carpal ligament. After surgery, the best predictors of return to work and to activities of daily living were strength and tenderness variables. For patients in the device group with one affected hand, the median time for return to work was 21 1/2 days less than that for the control group. Two patients treated with the endoscopic device required reoperation by open surgical decompression; only one of these had incomplete release with the device. Two patients in the device group experienced transient ulnar neurapraxia.
A study of the two-body decays B±→Xcc¯K±, where Xcc¯ refers to one charmonium state, is reported by the BABAR Collaboration using a data sample of 424 fb−1. The absolute determination of branching ...fractions for these decays are significantly improved compared to previous BABAR measurements. Evidence is found for the decay B+→X(3872)K+ at the 3σ level. The absolute branching fraction BB+→X(3872)K+=2.1±0.6(stat)±0.3(syst)×10−4 is measured for the first time. It follows that BX(3872)→J/ψπ+π−=(4.1±1.3)%, supporting the hypothesis of a molecular component for this resonance.
We report on the first search for electron-muon lepton flavor violation (LFV) in the decay of a b quark and b antiquark bound state. We look for the LFV decay Υ(3S)→e±μ∓ in a sample of 118 million ...Υ(3S) mesons from 27 fb-1 of data collected with the BABAR detector at the SLAC PEP-II e+e- collider operating with a 10.36 GeV center-of-mass energy. No evidence for a signal is found, and we set a limit on the branching fraction BΥ(3S)→e±μ∓<3.6×10-7 at 90% C. L. This result can be interpreted as a limit ΛNP/gNP2>80 TeV on the energy scale ΛNP divided by the coupling-squared gNP2 of relevant new physics (NP).
Safety was evaluated for collagenase Clostridium histolyticum (CCH) based on 11 clinical trials (N = 1082) and compared with fasciectomy data in a structured literature review of 48 European studies ...(N = 7727) for treatment of Dupuytren’s contracture. Incidence of adverse events was numerically lower with CCH vs. equivalent complications from fasciectomy (median range incidence), including nerve injury (0% vs. 3.8% 0%−50+%), neurapraxia (4.4% vs. 9.4% 0%−51.3%), complex regional pain syndrome (0.1% vs. 4.5% 1.3%−18.5%) and arterial injury (0% vs. 5.5% 0.8%−16.5%). Tendon injury (0.3% vs. 0.1% 0%−0.2%), skin injury (16.2% vs. 2.8% 0%−25.9%) and haematoma (77.7% vs. 2.0% 0%−25%) occurred at a numerically higher incidence with CCH than surgery. Adverse events in CCH trials not reported after fasciectomy included peripheral oedema; extremity pain; injection site pain, haemorrhage and swelling; tenderness; pruritus and lymphadenopathy. CCH-related adverse events were reported as predominantly injection-related and transient. These results may support clinical decision-making for treatment of Dupuytren’s contracture.
Hand function following single ray amputation Peimer, Clayton A.; Wheeler, Dale R.; Barrett, Amy ...
The Journal of hand surgery (American ed.),
11/1999, Letnik:
24, Številka:
6
Journal Article
Although severe intra-articular fractures of the distal radius are often treated with external fixation/distraction, little attention has been devoted to the amount and duration of fixator ...distraction required to maximize outcome. To determine these effects, we conducted a retrospective study of 26 patients whose primary treatment was external fixation/distraction. Patients were evaluated by chart review, questionnaire, x-ray films, and physical examination an average of 104 weeks after injury. The carpal height index was used to quantify distraction. Scores for pain, function, wrist motion, and grip strength and the total score were adversely affected in proportion to the increase in carpal height index by distraction. Outcome was adversely affected as the duration of distraction increased. Motion scores were affected most. Overall, patients recovered at least 75% of motion and grip strength, and 85% attained New York Orthopedic Hospital grades of good or excellent. These are the first data to show that there are potential adverse effects from increasing amounts of distraction and prolonged use of the external fixator.
We measured pressure changes in Guyon's canal and the carpal tunnel before and after endoscopic (11 cases) and open (10) carpal tunnel release. We found that release of the flexor retinaculum by ...endoscopic and open techniques measurably decreased pressure in both the carpal tunnel and Guyon's canal. This study provides an explanation for relief of ulnar tunnel syndrome symptoms following carpal tunnel release and may indicate that carpal tunnel release alone may be sufficient to provide symptomatic relief for most patients with carpal and ulnar tunnel syndromes.
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