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zadetkov: 8
1.
  • Predicting Cancer-Specific ... Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality
    Jerby-Arnon, Livnat; Pfetzer, Nadja; Waldman, Yedael Y. ... Cell, 08/2014, Letnik: 158, Številka: 5
    Journal Article
    Recenzirano
    Odprti dostop

    Synthetic lethality occurs when the inhibition of two genes is lethal while the inhibition of each single gene is not. It can be harnessed to selectively treat cancer by identifying inactive genes in ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP

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2.
  • Effects of a ketogenic diet... Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial
    Schmidt, Melanie; Pfetzer, Nadja; Schwab, Micheal ... Nutrition & metabolism, 07/2011, Letnik: 8, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Background: Tumor patients exhibit an increased peripheral demand of fatty acids and protein. Contrarily, tumors utilize glucose as their main source of energy supply. Thus, a diet supplying the ...
Celotno besedilo
Dostopno za: DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK, VSZLJ

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3.
  • Growth of human gastric can... Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides
    Otto, Christoph; Kaemmerer, Ulrike; Illert, Bertram ... BMC cancer, 04/2008, Letnik: 8, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Among the most prominent metabolic alterations in cancer cells are the increase in glucose consumption and the conversion of glucose to lactic acid via the reduction of pyruvate even in the presence ...
Celotno besedilo
Dostopno za: DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK

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4.
  • Improving the metabolic fid... Improving the metabolic fidelity of cancer models with a physiological cell culture medium
    Vande Voorde, Johan; Ackermann, Tobias; Pfetzer, Nadja ... Science advances, 01/2019, Letnik: 5, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Currently available cell culture media may not reproduce the in vivo metabolic environment of tumors. To demonstrate this, we compared the effects of a new physiological medium, Plasmax, with ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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5.
  • TKTL1 expression in human m... TKTL1 expression in human malign and benign cell lines
    Kämmerer, Ulrike; Gires, Olivier; Pfetzer, Nadja ... BMC cancer, 2015-Jun-10, 2015-6-10, 20150610, Letnik: 15, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Overexpression of transketolase-like 1 protein TKTL1 in cancer cells has been reported to correlate with enhanced glycolysis and lactic acid production. Furthermore, enhanced TKTL1 expression was put ...
Celotno besedilo
Dostopno za: DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK

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6.
  • Identifizierung und Testung spezifischer Inhibitoren des Energiestoffwechsels von Tumorzellen
    Pfetzer, Nadja
    Dissertation
    Odprti dostop

    Charakteristisch für viele maligne Tumorzellen ist eine erhöhte Aufnahme von Glucose und die Bildung großer Mengen Milchsäure auch in Anwesenheit von Sauerstoff (Warburg Effekt) und eine verminderte ...
Celotno besedilo
7.
  • TKTL1 expression in human malign and benign cell lines
    Kämmerer, Ulrike; Gires, Olivier; Pfetzer, Nadja ... BMC Cancer, 01/2015
    Journal Article
    Odprti dostop

    Background: Overexpression of transketolase-like 1 protein TKTL1 in cancer cells has been reported to correlate with enhanced glycolysis and lactic acid production. Furthermore, enhanced TKTL1 ...
Celotno besedilo

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Celotno besedilo
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zadetkov: 8

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