A critical review of the literature highlighted the need for a new taxonomy encompassing the most relevant barriers stemmed from previous studies, and accounting for interactions and independences of ...the barriers to avoid overlaps and implicit interactions. Based on an extensive literature review the paper provides a novel approach for barriers to the adoption of industrial energy-efficient technologies, coping with the issues risen by the review of the literature. We developed a taxonomy adaptable to empirical research, and able to evaluate the differences between perceived and real barriers, the effect of the barriers on decision-making processes, and the interactions among barriers. We modeled three types of interactions, i.e., causal relationship, composite effect and hidden effect, in order to start analyzing the dynamics among barriers, and tested the taxonomy in a preliminary investigation. The study proposes a useful instrument both to enterprises and policy-makers to identify critical factors to improve industrial energy efficiency and to open the research to further investigation in this topic.
We have combined the extended X-ray absorption fine structure (EXAFS) and X-ray emission spectroscopy (XES) to investigate the local structure and the local iron magnetic moments of (Li
1−
x
Fe
x
...)OHFeSe (
x
∼0.2) superconductors. The local structure, studied by Fe K-edge EXAFS measurements, is found to be inhomogeneous that is characterized by different Fe-Se bond lengths. The inhomogeneous phase exhibits a peculiar temperature dependence with lattice anomalies in the local structural parameters at the critical temperature
T
c
(36 K) and at the spin density wave (SDW) transition temperature
T
N
(130 K). Fe Kβ XES shows iron to be in a low spin state with the local Fe magnetic moment evolving anomalously as a function of temperature. Apart from a quantitative measurement of the local structure of (Li
1−
x
Fe
x
)OHFeSe, providing direct evidence of nanoscale inhomogeneity, the results provide further evidence of the vital role that the coupled electronic, lattice and magnetic degrees of freedom play in the iron-based superconductors.
Anomalous local structure and magnetic moment of an inhomogeneous FeSe based superconductor indicating importance of the structure and magnetic correlations in these materials.
The aim is to critically review the more relevant evidence on the interrelationships between exercise and metabolic outcomes. The research questions addressed in the recent specific literature with ...the most relevant randomized controlled trials, meta-analysis and cohort studies are presented in three domains: aerobic exercise, resistance exercise, combined aerobic and resistance exercise. From this review appear that the effects of aerobic exercise are well established, and interventions with more vigorous aerobic exercise programs resulted in greater reductions in HbA
1c
, greater increase in VO
2max
and greater increase in insulin sensitivity. Considering the available evidence, it appears that resistance training could be an effective intervention to help glycemic control, especially considering that the effects of this form of intervention are comparable with what reported with aerobic exercise. Less studies have investigated whether combined resistance and aerobic training offers a synergistic and incremental effect on glycemic control; however, from the available evidences appear that combined exercise training seems to determine additional change in HbA
1c
that can be seen significant if compared with aerobic training alone and resistance training alone.
Context. In previous papers, we introduced our method for measuring chemical abundances from integrated-light spectra of globular clusters and applied it to a variety of extragalactic star clusters. ...Our work so far, however, has concentrated primarily on the optical range 4200 Å –6200 Å. Aims. Here we extend our analysis technique to the infrared and test it on an H-band spectrum of the massive globular cluster G280 in M 31. Methods. We simultaneously analyse an optical spectrum of G280, obtained with the HIRES spectrograph on the Keck I telescope, and an H-band spectrum obtained with NIRSPEC on Keck II. We discuss the sensitivity of our results to various modifications of the input assumptions, such as different line lists and isochrones and the possible presence of a metallicity spread in G280. Results. When using the most recent version of the Kurucz line list, we measure iron abundances of Fe/H = −0.68±0.02 from the optical spectrum and Fe/H = −0.60±0.07 from the infrared spectrum. These values agree well with previous spectroscopic determinations of the metallicity of G280. While the small difference between the optical and infrared measurements is insignificant given the uncertainties, it is also consistent with a metallicity spread similar to that observed in massive GCs such as ω Cen and G1, and also hinted at by the colour-magnitude diagram of G280. The optical and infrared spectra both indicate an α-enhancement of about 0.3–0.4 dex relative to solar-scaled abundances, as typically also observed in Milky Way GCs. Conclusions. From this analysis, it appears that our integrated-light analysis technique also performs well in the H-band. However, complications due to the presence of molecular bands and telluric contamination are more severe in the infrared, and accurate modelling of the coolest giants is more critical.
Since the first discovery of a broad-lined type Ic supernova (SN) with a long-duration gamma-ray burst (GRB) in 1998, fewer than fifty GRB-supernovae (SNe) have been discovered. The ...intermediate-luminosity Swift GRB 161219B and its associated supernova SN 2016jca, which occurred at a redshift of z = 0.1475, represents only the seventh GRB-SN to have been discovered within 1 Gpc, and hence provides an excellent opportunity to investigate the observational and physical properties of these very elusive and rare type of SN. As such, we present optical to near-infrared photometry and optical spectroscopy of GRB 161219B and SN 2016jca, spanning the first three months since its discovery. GRB 161219B exploded in the disk of an edge-on spiral galaxy at a projected distance of 3.4 kpc from the galactic centre. GRB 161219B itself is an outlier in the Ep,i − Eγ,iso plane, while SN 2016jca had a rest-frame, peak absolute V-band magnitude of MV = − 19.0 ± 0.1, which it reached after 12.3 ± 0.7 rest-frame days. We find that the bolometric properties of SN 2016jca are inconsistent with being powered solely by a magnetar central engine, and demonstrate that it was likely powered exclusively by energy deposited by the radioactive decay of nickel and cobalt into their daughter products, which were nucleosynthesised when its progenitor underwent core collapse. We find that 0.22 ± 0.08M⊙ of nickel is required to reproducethe peak luminosity of SN 2016jca, and we constrain an ejecta mass of 5.8 ± 0.3M⊙ and a kinetic energy of 5.1 ± 0.8 × 1052 erg. Finally, we report on a chromatic, pre-maximum bump in the g-band light curve, and discuss its possible origin.
Abstract The existence of a secondary (in addition to compact object mergers) source of heavy element ( r -process) nucleosynthesis, the core-collapse of rapidly rotating and highly magnetized ...massive stars, has been suggested by both simulations and indirect observational evidence. Here, we probe a predicted signature of r -process enrichment, a late-time (≳40 days post-burst) distinct red color, in observations of gamma-ray burst supernovae (GRB-SNe), which are linked to these massive star progenitors. We present optical to near-IR color measurements of four GRB-SNe at z ≲ 0.4, extending out to >500 days post-burst, obtained with the Hubble Space Telescope and large-aperture ground-based telescopes. Comparison of our observations to models indicates that GRBs 030329, 100316D, and 130427A are consistent with both no enrichment and producing 0.01–0.15 M ⊙ of r -process material if there is a low amount of mixing between the inner r -process ejecta and outer supernova (SN) layers. GRB 190829A is not consistent with any models with r -process enrichment ≥0.01 M ⊙ . Taken together the sample of GRB-SNe indicates color diversity at late times. Our derived yields from GRB-SNe may be underestimated due to r -process material hidden in the SN ejecta (potentially due to low mixing fractions) or the limits of current models in measuring r -process mass. We conclude with recommendations for future search strategies to observe and probe the full distribution of r -process produced by GRB-SNe.
Purpose
The aim of this review is to evaluate the effects of new technology used in the management of diabetes mellitus (DM), including the use of continuous glucose monitoring (CGM) and the ...administration of insulin through continuous subcutaneous insulin infusion (CSII), on male and female sexual function.
Methods
This narrative review was performed for all available prospective, retrospective and review articles, published up to June 2023 in PubMed. Data were extracted from the text and from the tables of the manuscript.
Results
Sexual dysfunctions are an underestimated comorbidity of DM in both male and female. Although erectile dysfunction (ED) is recognized by the guidelines as a complication of DM, female sexual dysfunction (FSD) is poorly investigated in clinical setting. In addition to the complications of DM, the different types of therapies can also influence male and female sexual response. Furthermore, insulin therapy can be administered through multiple-daily injections (MDI) or a CSII. The new technologies in the field of DM allow better glycemic control which results in a reduction in the occurrence or aggravation of complications of DM. Despite this evidence, few data are available on the impact of new technologies on sexual dysfunctions.
Conclusions
The use of DM technology might affect sexual function due to the risk of a worse body image, as well as discomfort related to CSII disconnection during sexual activity. However, the use is related to an improved metabolic control, which, in the long-term associates to a reduction in all diabetes complications, including sexual function.
The chemical composition of exhaled breath was examined for volatile organic compound (VOC) indicators of sexual arousal in human beings. Participants (12-male, 12-female) were shown a randomized ...series of three emotion-inducing 10-min film clips interspersed with 3-min neutral film clips. The films caused different arousals: sports film (positive-nonsexual); horror film (negative-nonsexual); and erotic (sexual) that were monitored with physiological measurements including genital response and temperature. Simultaneously the breath was monitored for VOC and CO
. While some breath compounds (methanol and acetone) changed uniformly irrespective of the film order, several compounds did show significant arousal associated changes. For both genders CO
and isoprene decreased in the sex clip. Some male individuals showed particularly strong increases of indole, phenol and cresol coincident with sexual arousal that decreased rapidly afterwards. These VOCs are degradation products of tyrosine and tryptophan, precursors for dopamine, noradrenalin, and serotonin, and therefore represent potential breath markers of sexual arousal.
Prader–Willi syndrome (PWS) is a genetic disorder caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region. The three main genetic subtypes are represented ...by paternal 15q11-q13 deletion, maternal uniparental disomy 15, and imprinting defect. Clinical picture of PWS changes across life stages. The main clinical characteristics are represented by short stature, developmental delay, cognitive disability and behavioral diseases. Hypotonia and poor suck resulting in failure to thrive are typical of infancy. As the subjects with PWS age, clinical manifestations such as hyperphagia, temperature instability, high pain threshold, hypersomnia and multiple endocrine abnormalities including growth hormone and thyroid-stimulating hormone deficiencies, hypogonadism and central adrenal insufficiency due to hypothalamic dysfunction occur. Obesity and its complications are the most common causes of morbidity and mortality in PWS. Several mechanisms for the aetiology of obesity in PWS have been hypothesized, which include aberration in hypothalamic pathways of satiety control resulting in hyperphagia, disruption in hormones regulating appetite and satiety and reduced energy expenditure. However, despite the advancement in the research field of the genetic basis of obesity in PWS, there are contradictory data on the management. Although it is mandatory to adopt obesity strategy prevention from infancy, there is promising evidence regarding the management of obesity in adulthood with current obesity drugs along with lifestyle interventions, although the data are limited. Therefore, the current manuscript provides a review of the current evidence on obesity and PWS, covering physiopathological aspects, obesity-related complications and conservative management.
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