Development of cough-relieving herbal teas Puodziūniene, Gene; Janulis, Valdimaras; Milasius, Arvydas ...
Medicina (Kaunas, Lithuania),
2005, Letnik:
41, Številka:
6
Journal Article
Recenzirano
Cough-relieving medicinal herbs in tea are used from ancient times. Mucilage present in them or secretion produced under the influence of the active substances covers the oral and throat mucosa ...soothing its irritability and relieving dry, tiresome cough. It is known that the mixtures of medicinal herbs (Specias) have a complex influence on the human organism and the rational combination of medicinal herbs can improve their curative action and decrease the undesirable side effects. Having summarized the properties of those medicinal herbs we decided to create two formulations of cough-relieving herbal tea. The first formulation consists of marshmallow roots, liquorice roots and lime flowers, the second -- of marshmallow roots, Iceland moss and lime flowers. The methods for identification and assay of the active substances in the compounds were applied. The purity of the mixtures was regulated by limitation of the loss on drying, total ash, microbial contamination, contamination with radionuclides, heavy metals, pesticides and foreign matter. The expiry date of both cough-relieving herbal teas was approved to be 2 years.
There was a purpose to create a composite ointment of proteolytic and antimicrobial activity, the formulation of which would contain the proteolytic enzyme procelan and the antimicrobial preparation ...with wide spectrum of action dioxidin. During the development of prodioxin ointment by means of biological experiments the optimal concentration of dioxidin was evaluated; it was 1 percent. The optimal dispersity value of dioxidin particles was estimated by dialysis through a semipermeable membrane. The best release of dioxidine from prodioxin ointment occurred, when it was pulverized to particles with diameter 5-10 mm. The method of assay of dioxidin was modified for the ointment. The physicomechanical properties of the prodioxin ointment: flowability, colloidal stability, thermostability and rheological properties were examined. The investigated ointment is non-newtonian in character, e.g. an elastic and plastic system and may be intended for use in dermatological practice. Medicinal enzymic and antimicrobial effects of the prodioxin ointment were compared with the healing effect of Iruksol ointment. The medicinal effect of the prodioxin ointment exceeded that of Iruksol ointment by one day. Judging by the results of the physicochemical analysis a conclusion can be made that the prodioxin ointment is stable for two years at room temperature.
Development of throat clearing herbal teas Puodziūniene, Gene; Janulis, Valdimaras; Milasius, Arvydas ...
Medicina (Kaunas, Lithuania),
2004, Letnik:
40, Številka:
8
Journal Article
Recenzirano
Medicinal herbs in tea for throat clearing are used from ancient times. Taking into consideration the bronchial mucus secretion stimulating and antispasmodic, antimicrobial, antiphlogistic and ...stimulating effect on the ciliated epithelium two new formulations of throat clearing herbal tea were originated. The first formulation consists of liquorice roots, sweet fennel and thyme, and the second one consists of pine gemmae, thyme and elder flowers. The methods for identification and assay of the active substances of the components were adapted. The purity of the mixtures was regulated by the limitation of the loss on drying, total ash, microbial contamination, contamination with radionuclides, heavy metals, pesticides and foreign matter. Expiry date of both throat clearing herbal teas was confirmed to be 2 years.
When investigating the release of procelan from diphilic, hydrophobic and hydrophilic basis we determined that the best release of the active substance is from hydrophilic basis. The macrogolic base ...when compared with methylcellulosic one shows clearly expressed osmotic properties and therefore is more suitable as a base for ointments intended to treat suppurative wounds. This was confirmed by treatment of experimentally excited suppurative wounds on rabbits. Hydrophilic ointments containing lyophilized procelan powders from 4 per cent to 20 per cent were examined. The most remarkable therapeutic effect reached with the ointment of macrogolic base, optimal concentration of procelan being 10 per cent. The method of assay of procelan in the ointment was created. The created dosage form is stable for three years at room temperature.
Leaves, flowers and fruits of single-styled hawthorn are used for production of pharmaceuticals with cardiotonic, coronary vasodilatoric and hypotensive action. Amount of flavonoids accumulated in ...crude drug of hawthorn is a parameter of quality.
To establish the difference in amounts of flavonoids accumulated in the crude drug of single-styled hawthorn.
Different examples of crude material from some Lithuanian regions were extracted with ethanol; flavonoids were measured by spectroscopic method and by HPLC (high performance liquid chromatography).
From 0.77% to 2.80% of flavonoids are determined in the leaves and flowers; amounts of hyperosid were 0.16-0.87%; vitexin-o-rhamnosid 0.14-0.40%; rutin 0.10-0.19%. Flavonoids maximum percent was determinate in crude material examples collected at the single-styled hawthorn flowering time; the decline of amounts of flavonoids accumulated in the crude material of hawthorn was determined from May to August (realization of correlation coefficient r=-0.90). Hyperosid maximum percent was determined in crude material examples collected at flowering time; the decline of amounts of hyperosid accumulated in the crude material was determined from May to August (r=-0,94). Amounts of rutin and vitexin-o-rhamnosid in leaves were less than flowers; there was the decline of amounts of rutin and vitexin-o-rhamnosid in leaves from May to August. The percent of flavonoids 0.09 to 0.24 is determined in fruits.
Lithuanian single-styled hawthorn populations can supply quality crude material from May to August; the bigger amounts of flavonoids were determined in crude drug examples collected at flowering time.
