•Proposed a deep learning model for automatic detection of atrial fibrillation.•An end-to-end model using CNN and RNN was developed to extract high level features.•The model was trained and validated ...on three different publicly available databases.•A post-processing scheme was also used to reduce the number of false positives.
Goal: To develop a robust and real-time approach for automatic detection of atrial fibrillation (AF) in long-term electrocardiogram (ECG) recordings using deep learning (DL). Method: An end-to-end model combining the Convolutional- and Recurrent-Neural Networks (CNN and RNN) was proposed to extract high level features from segments of RR intervals (RRIs) in order to classify them as AF or normal sinus rhythm (NSR). Results: The model was trained and validated on three different databases including a total of 89 subjects. It achieved a sensitivity and specificity of 98.98% and 96.95%, respectively, validated through a 5-fold cross-validation. Additionally, the proposed model was found to be computationally efficient and it was capable of analyzing 24 h of ECG recordings in less than one second. The proposed algorithm was also tested on the unseen datasets to examine its robustness in detecting AF for new recordings which resulted in 98.96% and 86.04% for specificity and sensitivity, respectively. Conclusion: Compared to the state-of-the-art models evaluated on standard benchmark ECG datasets, the proposed model produced better performance in detecting AF. Additionally, since the model learns features directly from the data, it avoids the need for clever/cumbersome feature engineering.
•We proposed a deep learning model for electrocardiogram signals delineation.•An end-to-end model using CNN and LSTM were designed to extract high level features.•The model was trained and validated ...on two different publicly available databases.•DENS-ECG model shows a high performance in electrocardiogram signals delineation.
With the technological advancements in the field of tele-health monitoring, it is now possible to gather huge amount of electro-physiological signals such as the electrocardiogram (ECG). It is therefore necessary to develop models/algorithms that are capable of analysing these massive amount of data in real-time. This paper proposes a deep learning model for real-time segmentation of heartbeats.
The proposed DENS-ECG algorithm, combines convolutional neural network (CNN) and long short-term memory (LSTM) model to detect onset, peak, and offset of different heartbeat waveforms such as the P-waves, QRS complexes, T-waves, and No waves (NW). Using ECG as the inputs, the model learns to extract high level features through the training process, which, unlike other classical machine learning based methods, eliminates the feature engineering step.
The proposed DENS-ECG model was trained and validated on a dataset with 105 ECG records of length 15 min each and achieved an average sensitivity and precision of 97.95% and 95.68%, respectively, using a stratified 5-fold cross validation. Additionally, the model was evaluated on an unseen dataset to examine its robustness in QRS detection, which resulted in a sensitivity of 99.61% and precision of 99.52%.
The empirical results show the flexibility and accuracy of the combined CNN-LSTM model for ECG signal delineation.
This paper proposes an efficient and easy to use approach using deep learning for heartbeat segmentation, which could potentially be used in real-time tele-health monitoring systems.
The EEG (Electroencephalogram) is a representative signal containing information about the condition of the brain. The shape of the wave may contain useful information about the state of the brain. ...However, the human observer can not directly monitor these subtle details. Besides, since bio-signals are highly subjective, the symptoms may appear at random in the time scale. Therefore, the EEG signal parameters, extracted and analyzed using computers, are highly useful in diagnostics. This work discusses the effect on the EEG signal due to music and reflexological stimulation.
In this work, nonlinear parameters like Correlation Dimension (CD), Largest Lyapunov Exponent (LLE), Hurst Exponent (H) and Approximate Entropy (ApEn) are evaluated from the EEG signals under different mental states.
The results obtained show that EEG to become less complex relative to the normal state with a confidence level of more than 85% due to stimulation.
It is found that the measures are significantly lower when the subjects are under sound or reflexologic stimulation as compared to the normal state. The dimension increases with the degree of the cognitive activity. This suggests that when the subjects are under sound or reflexologic stimuli, the number of parallel functional processes active in the brain is less and the brain goes to a more relaxed state
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
In a c-VEP BCI setting, test subjects can have highly varying performances when different pseudorandom sequences are applied as stimulus, and ideally, multiple codes should be supported. On the other ...hand, repeating the experiment with many different pseudorandom sequences is a laborious process.
This study aimed to suggest an efficient method for choosing the optimal stimulus sequence based on a fast test and simple measures to increase the performance and minimize the time consumption for research trials.
A total of 21 healthy subjects were included in an online wheelchair control task and completed the same task using stimuli based on the m-code, the gold-code, and the Barker-code. Correct/incorrect identification and time consumption were obtained for each identification. Subject-specific templates were characterized and used in a forward-step first-order model to predict the chance of completion and accuracy score.
No specific pseudorandom sequence showed superior accuracy on the group basis. When isolating the individual performances with the highest accuracy, time consumption per identification was not significantly increased. The Accuracy Score aids in predicting what pseudorandom sequence will lead to the best performance using only the templates. The Accuracy Score was higher when the template resembled a delta function the most and when repeated templates were consistent. For completion prediction, only the shape of the template was a significant predictor.
The simple and fast method presented in this study as the Accuracy Score, allows c-VEP based BCI systems to support multiple pseudorandom sequences without increase in trial length. This allows for more personalized BCI systems with better performance to be tested without increased costs.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Being an inter-disciplinary subject, Signal Processing has application in almost all scientific fields. Applied Signal Processing tries to link between the analog and digital signal processing ...domains. Since the digital signal processing techniques have evolved from its analog counterpart, this book begins by explaining the fundamental concepts in analog signal processing and then progresses towards the digital signal processing. This will help the reader to gain a general overview of the whole subject and establish links between the various fundamental concepts. While the focus of this book is on the fundamentals of signal processing, the understanding of these topics greatly enhances the confident use as well as further development of the design and analysis of digital systems for various engineering and medical applications. Applied Signal Processing also prepares readers to further their knowledge in advanced topics within the field of signal processing.
We have witnessed a rapid development of brain-computer interfaces (BCIs) linking the brain to external devices. BCIs can be utilized to treat neurological conditions and even to augment brain ...functions. BCIs offer a promising treatment for mental disorders, including disorders of attention. Here we review the current state of the art and challenges of attention-based BCIs, with a focus on visual attention. Attention-based BCIs utilize electroencephalograms (EEGs) or other recording techniques to generate neurofeedback, which patients use to improve their attention, a complex cognitive function. Although progress has been made in the studies of neural mechanisms of attention, extraction of attention-related neural signals needed for BCI operations is a difficult problem. To attain good BCI performance, it is important to select the features of neural activity that represent attentional signals. BCI decoding of attention-related activity may be hindered by the presence of different neural signals. Therefore, BCI accuracy can be improved by signal processing algorithms that dissociate signals of interest from irrelevant activities. Notwithstanding recent progress, optimal processing of attentional neural signals remains a fundamental challenge for the development of efficient therapies for disorders of attention.
Stroke is one of the most common neurological conditions that often leads to upper limb motor impairments, significantly affecting individuals' quality of life. Rehabilitation strategies are crucial ...in facilitating post-stroke recovery and improving functional independence. Functional Electrical Stimulation (FES) systems have emerged as promising upper limb rehabilitation tools, offering innovative neuromuscular reeducation approaches.
The main objective of this paper is to provide a comprehensive systematic review of the start-of-the-art functional electrical stimulation (FES) systems for upper limb neurorehabilitation in post-stroke therapy. More specifically, this paper aims to review different types of FES systems, their feasibility testing, or randomized control trials (RCT) studies.
The FES systems classification is based on the involvement of patient feedback within the FES control, which mainly includes "Open-Loop FES Systems" (manually controlled) and "Closed-Loop FES Systems" (brain-computer interface-BCI and electromyography-EMG controlled). Thus, valuable insights are presented into the technological advantages and effectiveness of Manual FES, EEG-FES, and EMG-FES systems.
The review analyzed 25 studies and found that the use of FES-based rehabilitation systems resulted in favorable outcomes for the stroke recovery of upper limb functional movements, as measured by the FMA (Fugl-Meyer Assessment) (Manually controlled FES: mean difference = 5.6, 95% CI (3.77, 7.5),
< 0.001; BCI-controlled FES: mean difference = 5.37, 95% CI (4.2, 6.6),
< 0.001; EMG-controlled FES: mean difference = 14.14, 95% CI (11.72, 16.6),
< 0.001) and ARAT (Action Research Arm Test) (EMG-controlled FES: mean difference = 11.9, 95% CI (8.8, 14.9),
< 0.001) scores. Furthermore, the shortcomings, clinical considerations, comparison to non-FES systems, design improvements, and possible future implications are also discussed for improving stroke rehabilitation systems and advancing post-stroke recovery. Thus, summarizing the existing literature, this review paper can help researchers identify areas for further investigation. This can lead to formulating research questions and developing new studies aimed at improving FES systems and their outcomes in upper limb rehabilitation.
ECG is a non-invasive tool for arrhythmia detection. In recent years, wearable ECG-based ambulatory arrhythmia monitoring has gained increasing attention. However, arrhythmia detection algorithms ...trained on existing public arrhythmia databases show higher FPR when applied to such ambulatory ECG recordings. It is primarily because the existing public databases are relatively clean as they are recorded using clinical-grade ECG devices in controlled clinical environments. They may not represent the signal quality and artifacts present in ambulatory patient-operated ECG. To help build and evaluate arrhythmia detection algorithms that can work on wearable ECG from free-living conditions, we present the design and development of the CACHET-CADB, a multi-site contextualized ECG database from free-living conditions. The CACHET-CADB is subpart of the REAFEL study, which aims at reaching the frail elderly patient to optimize the diagnosis of atrial fibrillation. In contrast to the existing databases, along with the ECG, CACHET-CADB also provides the continuous recording of patients' contextual data such as activities, body positions, movement accelerations, symptoms, stress level, and sleep quality. These contextual data can aid in improving the machine/deep learning-based automated arrhythmia detection algorithms on patient-operated wearable ECG. Currently, CACHET-CADB has 259 days of contextualized ECG recordings from 24 patients and 1,602 manually annotated 10 s heart-rhythm samples. The length of the ECG records in the CACHET-CADB varies from 24 h to 3 weeks. The patient's ambulatory context information (activities, movement acceleration, body position, etc.) is extracted for every 10 s interval cumulatively. From the analysis, nearly 11% of the ECG data in the database is found to be noisy. A software toolkit for the use of the CACHET-CADB is also provided.
This paper describes the implementation of a Brain Computer Interface (BCI) scheme using a common spatial patterns (CSP) filter in combination with a Recursive Least Squares (RLS) approach to ...iteratively update the coefficients of the CSP filter. The proposed adaptive CSP (ACSP) algorithm is made more robust by introducing regularization using Diagonal Loading (DL), and thus will be able to significantly reduce the length of training sessions when introducing new patients to the BCI system. The system is tested on a 4-class multi-limb motor imagery (MI) data set from the BCI competition IV (2a), and a more complex single limb 3-class MI dataset recorded in-house. The latter dataset is produced to mimic an upper limb rehabilitation session, e.g., after stroke. The findings indicate that when extensive calibration data is available, the ACSP performs comparably to the CSP (kappa value of 0.523 and 0.502, respectively, for the 4-class problem); for reduced calibration sessions, the ACSP significantly improved the performance of the system (up to 4-fold). The proposed paradigm proved feasible and the ACSP algorithm seems to enable a user or semi user independent scenario, where the need for long system calibration sessions without feedback is eliminated.
•Adaptation in common spatial pattern filters reduces the need for long offline sessions.•A Recursive Least Squares approach is used for adaptation.•Diagonal Loading is used to stabilize the adaptation.•With abundant training data, this method performs as well as non-adaptive methods.•On small training data, it significantly outperforms non-adaptive methods.
Objectives: Develop an effective and intuitive Graphical User Interface (GUI) for a Brain–Computer Interface (BCI) system, that achieves high classification accuracy and Information Transfer Rates ...(ITRs), while using a simple classification technique. Objectives also include the development of an output device, that is capable of real time execution of the selected commands.
A region based T9 BCI system with familiar face presentation cues capable of eliciting strong P300 responses was developed. Electroencephalogram (EEG) signals were collected from the Oz, POz, CPz and Cz electrode locations on the scalp and subsequently filtered, averaged and used to extract two features. These feature sets were classified using the Nearest Neighbour Approach (NNA). To complement the developed BCI system, a ‘drone prototype’ capable of simulating six different movements, each over a range of eight distinct selectable distances, was also developed. This was achieved through the construction of a body with 4 movable legs, capable of tilting the main body forward, backward, up and down, as well as a pointer capable of turning left and right.
From ten participants, with normal or corrected to normal vision, an average accuracy of 91.3 ± 4.8% and an ITR of 2.2 ± 1.1 commands/minute (12.2 ± 6.0 bits/minute) was achieved.
The proposed system was shown to elicit strong P300 responses. When compared to similar P300 BCI systems, which utilise a variety of more complex classifiers, competitive accuracy and ITR results were achieved, implying the superiority of the proposed GUI. Significance: This study supports the hypothesis that more research, time and care should be taken when developing GUIs for BCI systems.
•A GUI for BCI systems capable of high ITRs is proposed.•A novel T9, 2 stage interfaces were developed, consisting of 50 output commands.•The model tested on 10 subjects showed competitive ITRs and accuracies.•Developed a prototype drone as a proof-of-concept for real-time locomotive control.
PDF
