The convenience and efficiency of cloud computing have brought great potential for its development.More and more enterprises and individuals obtain real benefits by using various outsourcing services ...provided by cloud computing.In order to protect the confidentiality and integrity of outsourced data in the cloud, the keyword search over encrypted cloud data with privacy protection and integrity verification is becoming a research hotspot in the field of cloud computing.In this paper, we focus on the issue of the verifiable keyword search over encrypted data.The system models, threat models and frameworks adopted in the existing works are firstly introduced.Related works are overviewed from the aspects of verifiable single keyword search and verifiable multi-keyword search over encrypted data, and the ideas of these works are briefly described together with the advantages and disadvantages.At last, the conclusion is presented through a comprehensive analysis and comparison of the related works, and the possibl
The successful launched Gaofen satellite no. 1 wide field-of-view （GF-1 WFV） camera is characterized by its high spatial resolution and may provide some potential for regional crop mapping. This ...study, taking the Bei＇an City, Northeast China as the study area, aims to investigate the potential of GF-1 WFV images for crop identification and explore how to fully use its spectral, textural and temporal information to improve classification accuracy. In doing so, an object-based and Random Forest （RF） algorithm was used for crop mapping. The results showed that classification based on an optimized single temporal GF-1 image can achieve an overall accuracy of about 83%, and the addition of textural features can im- prove the accuracy by 8.14%. Moreover, the multi-temporal GF-1 data can produce a classification map of crops with an overall accuracy of 93.08% and the introduction of textural variables into multi-temporal GF-1 data can only increase the accuracy by about 1%, which suggests the importance of temporal information of GF-1 for crop mapping in comparison with single temporal data. By comparing classification results of GF-1 data with different feature inputs, it is concluded that GF-1 WFV data in general can meet the mapping efficiency and accuracy requirements of regional crop. But given the unique spectral characteristics of the GF-1 WFV imagery, the use of textual and temporal information is needed to yield a satisfactory accuracy.
AIM： To evaluate preoperative double-balloon enteroscopy for determining bleeding lesions of small intestine, thus directing selective surgical intervention. METHODS： We retrospectively reviewed 56 ...patients who underwent double-balloon enteroscopy to localize intestinal bleeding prior to surgical intervention, and compared enteroscopic findings with those of intraoperation to determine the accuracy of enteroscopy in identifying and localizing the sites of small intestinal bleeding. RESULTS： Double-balloon enteroscopy was performed in all 56 patients in a 30-mo period. A possible site of blood loss was identified in 54 （96%） patients. Enteroscopy provided accurate localization of the bleeding in 53 （95%） of 56 patients, but failed to disclose the cause of bleeding in 4 （7%）. There was one case with negative intraoperative finding （2%）. Resection of the affected bowel was carried out except one patient who experienced rebleeding after operation. Gastrointestinal stromal tumor （GIST） was most frequently diagnosed （55%）. CONCLUSION： Double-balloon enteroscopy is a safe, reliable modality for determining bleeding lesion of small intestine. This technique can be used to direct selective surgical intervention.
We investigate the co-propagation of a strong pump beam and a weak signal beam in lead glass, and find that the large phase shift of the strongly nonlocal spatial optical soliton （SNSOS） can be ...realized via cross-phase modulation. The theoretical study suggests a synchronous propagation of the pump SNSOS and the signal SNSOS under the required initial condition. A π-phase shift of the signal SNSOS is experimentally obtained by changing the power of the pump SNSOS by about 13 mW around the soliton critical power, which agrees qualitatively with our theoretical prediction. The ratio of the phase shift rate of the signal SNSOS to that of the pump SNSOS shows a close match to the reciprocal of the ratio between their wavelengths.
In recent years, deep learning has presented a great advance in the hyperspectral image (HSI) classification. Particularly, long short-term memory (LSTM), as a special deep learning structure, has ...shown great ability in modeling long-term dependencies in the time dimension of video or the spectral dimension of HSIs. However, the loss of spatial information makes it quite difficult to obtain better performance. In order to address this problem, two novel deep models are proposed to extract more discriminative spatial-spectral features by exploiting the convolutional LSTM (ConvLSTM). By taking the data patch in a local sliding window as the input of each memory cell band by band, the 2-D extended architecture of LSTM is considered for building the spatial-spectral ConvLSTM 2-D neural network (SSCL2DNN) to model long-range dependencies in the spectral domain. To better preserve the intrinsic structure information of the hyperspectral data, the spatial-spectral ConvLSTM 3-D neural network (SSCL3DNN) is proposed by extending LSTM to the 3-D version for further improving the classification performance. The experiments, conducted on three commonly used HSI data sets, demonstrate that the proposed deep models have certain competitive advantages and can provide better classification performance than the other state-of-the-art approaches.
Secreted protein, acidic and rich in cysteine （SPARC） is expressed in numerous types of tumors and is suggested to have prognostic value. Moreover, because of its strong affinity for albumin, and ...hence albumin-bound drugs, SPARC has increasingly become a focus for research. In this study, we aimed to determine SPARC expression in patients with non-small cell lung cancer （NSCLC） and investigate the association of SPARC with disease prognosis. Tissue microarrays were constructed with specimens from 105 patients with NSCLC treated at Sun Yat-sen University Cancer Center, and immunohistochemical analysis was performed on these tissue microarrays to assess SPARC expression. Our results showed that SPARC expression status did not significantly relate with age, gender, and tumor stage. However, SPARC was expressed more frequently in squamous cell carcinoma than in adenocarcinoma （75% vs. 43.5%, P = 0.004）. Patients with smoking history had higher SPARC expression than non-smokers （68.2% vs. 33.3%, P = 0.002）. In both univariate and multivariate analyses, SPARC was a prognostic factor of overall survival （HR = 0.32; 95% CI： 0.16-0.65） but not disease-free survival. Our study indicates that SPARC expression is higher in squamous cell carcinoma than in adenocarcinoma in NSCLC. Most notably, SPARC can be used as a prognostic factor for NSCLC.
Efficient hydrogen evolution via electrocatalytic water splitting holds great promise in modern energy devices. Herein, we demonstrate that the localized surface plasmon resonance (LSPR) excitation ...of Au nanorods (NRs) dramatically improves the electrocatalytic hydrogen evolution activity of CoFe‐metal–organic framework nanosheets (CoFe‐MOFNs), leading to a more than 4‐fold increase of current density at −0.236 V (vs. RHE) for Au/CoFe‐MOFNs composite under light irradiation versus in dark. Mechanistic investigations reveal that the hydrogen evolution enhancement can be largely attributed to the injection of hot electrons from AuNRs to CoFe‐MOFNs, raising the Fermi level of CoFe‐MOFNs, facilitating the reduction of H2O and affording decreased activation energy for HER. This study highlights the superiority of plasmonic excitation on improving electrocatalytic efficiency of MOFs and provides a novel avenue towards the design of highly efficient water‐splitting systems under light irradiation.
Some like it hot: A composite of Au nanorods/CoFe‐MOF nanosheets (Au/CoFe‐MOFNs) was used as an electrocatalyst for the hydrogen evolution reaction (HER). Au/CoFe‐MOFNs give a four‐fold increase of current density and a much reduced activation energy upon light irradiation as a result of hot‐electron injection from plasmonic Au to CoFe‐MOFNs.
Background： The clotting system abnormalities are the common complication in cancer patients. The aim of this retrospective study was to evaluate the coagulation state, clinical features, and ...treatment in cancer patients by routine tests. Methods： A total of 2328 patients with different types of cancer were classified as the positive group （n = 1419, including 53 patients with thrombosis） and the negative group （n = 909） based on D-dimer （DD） value. Of the 2328 cases, 354 were admitted for chemotherapy. Hemostasis test and complete blood count （CBC） were perfbrmed during treatment or following-up. Results： This study showed that the hypercoagulable state was affected not only by clinical staging （P 〈 0,0001） but also by metastasis site （P 〈 0.0001 for bone vs. lung）. Compared to negative DD group, the higher fibrinogen level, the extended activated partial thromboplastin time, and prothrombin time interacted markedly with disease clinical stage （P 〈 0.05） in the positive group. Between positive DD groups with and without thrombus, the significantly statistic difference in white blood cell （WBC） and DD （P 〈 0.05） rather than in red blood cell （RBC） and platelet count was observed. However, the higher DD level was not correlated with WBC, RBC, and platelet count in the positive DD group. Furthermore, the hypercoagulable plasma profile in cancer patients was moderated 2-3 weeks alter chemotherapy （P 〈 0.05 for first six cycles）. Conclusions： The routine hemostatic parameters and CBC are valuable to assessment for thrombosis and chemotherapy even for disease prognosis.
During embryo implantation, apoptosis is inevitable. These apoptotic cells (ACs) are removed by efferocytosis, in which macrophages are filled with a metabolite load nearly equal to the phagocyte ...itself. A timely question pertains to the relationship between efferocytosis-related metabolism and the immune behavior of decidual macrophages (dMΦs) and its effect on pregnancy outcome. Here, we report positive feedback of IL-33/ST2-AXL-efferocytosis leading to pregnancy failure through metabolic reprogramming of dMΦs. We compared the serum levels of IL-33 and sST2, along with IL-33 and ST2, efferocytosis and metabolism of dMΦs, from patients with normal pregnancies and unexplained recurrent pregnancy loss (RPL). We revealed disruption of the IL-33/ST2 axis, increased apoptotic cells and elevated efferocytosis of dMΦs from patients with RPL. The dMΦs that engulfed many apoptotic cells secreted more sST2 and less TGF-β, which polarized dMΦs toward the M1 phenotype. Moreover, the elevated sST2 biased the efferocytosis-related metabolism of RPL dMΦs toward oxidative phosphorylation and exacerbated the disruption of the IL-33/ST2 signaling pathway. Metabolic disorders also lead to dysfunction of efferocytosis, resulting in more uncleared apoptotic cells and secondary necrosis. We also screened the efferocytotic molecule AXL regulated by IL-33/ST2. This positive feedback axis of IL-33/ST2-AXL-efferocytosis led to pregnancy failure. IL-33 knockout mice demonstrated poor pregnancy outcomes, and exogenous supplementation with mouse IL-33 reduced the embryo losses. These findings highlight a new etiological mechanism whereby dMΦs leverage immunometabolism for homeostasis of the microenvironment at the maternal–fetal interface.
Graphyne, a theorized carbon allotrope possessing only sp‐ and sp2‐hybridized carbon atoms, holds great potentials in many fields, especially in catalysis and energy‐transfer/storage devices. Using a ...bottom‐up strategy, we synthesized a new N‐doped graphyne analogue, triazine‐ and 1,4‐diethynylbenzene‐based graphyne TA‐BGY, in solution in gram‐scale. The unique sp/sp2 carbon‐conjugated TA‐BGY possesses an extended porous network structure with a BET surface area of approximately 300 m2 g−1. Owing to its low optical band gap (1.44 eV), TA‐BGY was expected to have many applications, which were exemplified by the photodegradation of methyl orange and photocatalytic bacterial inactivation.
Antibiosis: N‐doped graphyne analogues, triazine‐ and 1,4‐diethynylbenzene‐based graphyne (TA‐BGY), were synthesized through aromatic nucleophilic substitution reactions. TA‐BGY was expected to have many applications that were exampled by the photodegradation of methyl orange (99 %) and photocatalytic bacterial inactivation (see figure).
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