1.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
2.
Reproductive outcomes in women with congenital uterine anomalies: a systematic review
Chan, Y. Y.; Jayaprakasan, K.; Tan, A. ...
Ultrasound in obstetrics & gynecology,
October 2011, Letnik:
38, Številka:
4
Journal Article
Objective
Congenital uterine anomalies are common but their effect on reproductive outcome is unclear. We conducted a systematic review to evaluate the association between different types of ...
congenital uterine anomaly and various reproductive outcomes.
Methods
Searches were performed using MEDLINE, EMBASE, the Cochrane Library and Web of Science. The Newcastle‐Ottawa Quality Assessment Scale was used for quality assessment. Uterine defects were grouped into arcuate uteri, canalization defects (septate and subseptate uteri) and unification defects (unicornuate, bicornuate and didelphys uteri). Pooled risk ratios (RR) with 95% confidence intervals (CI) were computed using random effects models.
Results
We identified nine studies comprising 3805 women. Meta‐analysis showed that arcuate uteri were associated with increased rates of second‐trimester miscarriage (RR, 2.39; 95% CI, 1.33–4.27, P = 0.003) and fetal malpresentation at delivery (RR, 2.53; 95% CI, 1.54–4.18; P < 0.001). Canalization defects were associated with reduced clinical pregnancy rates (RR, 0.86; 95% CI, 0.77–0.96; P = 0.009) and increased rates of first‐trimester miscarriage (RR, 2.89; 95% CI; 2.02–4.14; P < 0.001), preterm birth (RR, 2.14; 95% CI, 1.48–3.11; P < 0.001) and fetal malpresentation (RR, 6.24; 95% CI, 4.05–9.62; P < 0.001). Unification defects were associated with increased rates of preterm birth (RR, 2.97; 95% CI, 2.08–4.23; P < 0.001) and fetal malpresentation (RR, 3.87; 95% CI, 2.42–6.18; P < 0.001).
Conclusions
Canalization defects reduce fertility and increase rates of miscarriage and preterm delivery. None of the unification defects reduces fertility but some are associated with miscarriage and preterm delivery. Arcuate uteri are specifically associated with second‐trimester miscarriage. All uterine anomalies increase the chance of fetal malpresentation at delivery. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
več
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
3.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
4.
Endometrial scratching performed in the non‐transfer cycle and outcome of assisted reproduction: a randomized controlled trial
Nastri, C. O.; Ferriani, R. A.; Raine‐Fenning, N. ...
Ultrasound in obstetrics & gynecology,
October 2013, Letnik:
42, Številka:
4
Journal Article
ABSTRACT
Objectives
To investigate the effect of endometrial scratching, performed during oral contraceptive pill (OCP) pretreatment, on reproductive outcome and on ultrasound markers of endometrial ...
receptivity, and to assess the pain involved in the procedure, in unselected women undergoing assisted reproductive techniques (ART).
Methods
Women undergoing ART were randomly allocated to undergo either endometrial scratching with a pipelle de Cornier or a sham procedure, 7–14 days before starting controlled ovarian stimulation (COS). We evaluated subsequent rates of clinical pregnancy, live birth, implantation, miscarriage and multiple pregnancy. Pain during the procedure was evaluated using a 10‐cm visual analog scale. Endometrial thickness and volume and three‐dimensional power Doppler (3D‐PD) indices (vascularization index (VI), flow index (FI) and vascularization flow index (VFI)) were assessed during COS when there was at least one follicle ≥ 17 mm in diameter.
Results
We included 158 women. Endometrial scratching was associated with higher rates of live birth (41.8% vs 22.8%, P = 0.01) and clinical pregnancy (49.4% vs 29.1%, P = 0.01) and higher pain score (6.42 ± 2.35 cm vs 1.82 ± 1.52 cm, P < 0.001), endometrial VI (3.71 ± 1.77 vs 2.95 ± 1.56, P < 0.01) and VFI (0.97 ± 0.51 vs 0.76 ± 0.40, P < 0.01). There was no significant effect of endometrial scratching on rate of miscarriage (15.4% vs 21.7%, P = 0.53) or multiple pregnancy (22.5% vs 25.0%, P = 0.79), or on endometrial thickness (10.12 ± 1.55 mm vs 9.98 ± 1.62 mm, P = 0.59), endometrial volume (6.18 ± 1.63 cm3 vs 6.01 ± 1.48 cm3, P = 0.51) or FI (26.12 ± 2.82 vs 25.91 ± 2.72, P = 0.65).
Conclusions
Endometrial scratching performed once, during OCP pretreatment 7–14 days before starting COS, increases the chance of live birth and clinical pregnancy, but might cause considerable pain. Copyright © 2013 ISUOG. Published by John Wiley & Sons Ltd.
več
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
5.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
6.
The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review
Chan, Y.Y; Jayaprakasan, K; Zamora, J ...
Human reproduction update,
11/2011, Letnik:
17, Številka:
6
Journal Article
BACKGROUND
The prevalence of congenital uterine anomalies in high-risk women is unclear, as several different diagnostic approaches have been applied to different groups of patients. This review aims ...
to evaluate the prevalence of such anomalies in unselected populations and in women with infertility, including those undergoing IVF treatment, women with a history of miscarriage, women with infertility and recurrent miscarriage combined, and women with a history of preterm delivery.
METHODS
Searches of MEDLINE, EMBASE, Web of Science and the Cochrane register were performed. Study selection and data extraction were conducted independently by two reviewers. Studies were grouped into those that used 'optimal' and 'suboptimal' tests for uterine anomalies. Meta-analyses were performed to establish the prevalence of uterine anomalies and their subtypes within the various populations.
RESULTS
We identified 94 observational studies comprising 89 861 women. The prevalence of uterine anomalies diagnosed by optimal tests was 5.5% 95% confidence interval (CI), 3.5-8.5 in the unselected population, 8.0% (95% CI, 5.3-12) in infertile women, 13.3% (95% CI, 8.9-20.0) in those with a history of miscarriage and 24.5% (95% CI, 18.3-32.8) in those with miscarriage and infertility. Arcuate uterus is most common in the unselected population (3.9%; 95% CI, 2.1-7.1), and its prevalence is not increased in high-risk groups. In contrast, septate uterus is the most common anomaly in high-risk populations.
CONCLUSIONS
Women with a history of miscarriage or miscarriage and infertility have higher prevalence of congenital uterine anomalies compared with the unselected population.
več
Dostopno za:
NUK, UL, UM, UPUK
7.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
8.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
9.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
10.
Dostopno za:
BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SBCE, SBMB, UL, UM, UPUK
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