Comparative ultrastructure of majoid spermatozoa belonging to 23 species, in 19 genera and five families, is considered, with new data on Schizophrys aspera; S. rufescens (Majidae, Majinae); ...Camposcia retusa (Inachidae); Pyromaia tuberculata (Inachoididae); and Huenia heraldica and Menaethius monoceros (Epialtidae, Epialtinae). The oregoniid Chionoecetes opilio, and inachids Cyrtomaia furici, Platymaia rebierei, Macropodia longirostris and Inachus phalangium, possibly with Camposcia retusa, but not Podochela riisei, appear to form a group. Within the inachids, Macropodia and Inachus are especially close. A domed central acrosome zone, seen in most inachid sperm, in majines (both Schizophrys species), in pisines (Oxypleurodon orbiculatus and O. stuckiae) and epialtines (Huenia heraldica and Menaethius monoceros), appears to be an autapomorphy of these majoids. A peripheral acrosome zone is seen in the inachid Grypacheus hyalinus, two inachoidids (P. tuberculata and Stenorhynchus seticornis) and the majid Maja squinado. Pyromaia tuberculata differs from other inachoidids in having a slightly dome‐shaped operculum. The mithracine Macrocoeloma trispinosum (Majidae) sperm more closely resembles Inachoididae, than Inachidae. Spermatologically, the family Majidae and the subfamily Majinae are not homogeneous. Spermatozoal ultrastructure does not support a majoid–hymenosomatid relationship and is equivocal with regard to the placement of Cryptochiridae in either the Thoracotremata or Heterotremata, the prominent operculum strongly differentiates cryptochirids from Majoidea.
NGC 6751 is a highly structured multiple-shell planetary nebula (PN) with a bipolar outflow. In this work, we present a comprehensive set of spatially resolved, high spectral resolution, long-slit ...spectra and deep imaging from San Pedro Martir, Gemini, the H Delta *a composite full sky survey and archive images from the Hubble Space Telescope and Spitzer. This material allows us to identify all the main morphological components and study their detailed kinematics. We find a thick equatorial structure fragmented into multiple knots that enclose a fast expanding bubble with a filamentary surface structure. The knotty ring is surrounded by faint emission from a disk-like envelope. Lobes with embedded filaments form a bipolar outflow. The equatorial ring is tilted with respect to the line of sight and with respect to the bipolar outflow. A spherical halo surrounds the PN and there is material further out identified as a fragmented outer halo. This information is used to derive a three-dimensional morpho-kinematic model using the code SHAPE that closely replicates the observed image and long-slit spectra of the nebula, providing a fair representation of its complex structure. NGC 6751 is located close to the galactic plane and its large-scale surrounding environment is shown to be a gas-rich region. We find indications that the PN is interacting with the interstellar medium. Emission components from an extended nebulosity located a couple of arcminutes away from the nebula have radial velocities that are inconsistent with the rest of NGC 6751 and are confirmed as originating from the ambient material, not related to the PN, in agreement with a previous suggestion.
Abstract Background Low flow (LF) can occur with reduced (classic) or preserved (paradoxical) left ventricular ejection fraction (LVEF). Objectives The objective of this study was to compare outcomes ...of patients with low ejection fraction (LEF), paradoxical low flow (PLF), and normal flow (NF) after aortic valve replacement (AVR). Methods We examined 1,154 patients with severe aortic stenosis (AS) who underwent AVR with or without coronary artery bypass grafting. Results Among these patients, 206 (18%) had LEF as defined by LVEF of <50%; 319 (28%) had PLF as defined by LVEF of ≥50% but stroke volume indexed to body surface area (SVi) of ≤35 ml ∙ m−2 ; and 629 (54%) had NF, as defined by LVEF of ≥50% and SVi of >35 ml ∙ m2 . Aortic valve area was lower in low flow/LVEF groups (LEF: 0.71 ± 0.20 cm2 and PLF: 0.65 ± 0.23 cm2 vs. NF: 0.77 ± 0.18 cm2 ; p < 0.001). The 30-day mortality was higher (p < 0.001) in LEF and PLF groups than in the NF group (6.3% and 6.3% vs. 1.8%, respectively). SVi and PLF group were independent predictors of operative mortality (odds ratio OR: 1.18, p < 0.05; and OR: 2.97, p = 0.004; respectively). At 5 years after AVR, overall survival was 72 ± 4% in LEF group, 81 ± 2% in PLF group, and 85 ± 2% in NF group (p < 0.0001). Conclusions Patients with LEF or PLF AS have a higher operative risk, but pre-operative risk score accounted only for LEF and lower LVEF. Patients with LEF had the worst survival outcome, whereas patients with PLF and normal flow had similar survival rates after AVR. As a major predictor of perioperative mortality, SVi should be integrated in AS patients’ pre-operative evaluation.
Stars form in the densest, coldest, most quiescent regions of molecular clouds. Molecules provide the only probes that can reveal the dynamics, physics, chemistry, and evolution of these regions, but ...our understanding of the molecular inventory of sources and how this is related to their physical state and evolution is rudimentary and incomplete. The Spectral Legacy Survey (SLS) is one of seven surveys recently approved by the James Clerk Maxwell Telescope (JCMT) Board of Directors. Beginning in 2007, the SLS will produce a spectral imaging survey of the content and distribution of all the molecules detected in the 345 GHz atmospheric window (between 332 and 373 GHz) toward a sample of five sources. Our intended targets are a low‐mass core (NGC 1333 IRAS 4), three high‐mass cores spanning a range of star‐forming environments and evolutionary states (W49, AFGL 2591, and IRAS 20126), and a photodissociation region (the Orion Bar). The SLS will use the unique spectral imaging capabilities of HARP‐B/ACSIS (Heterodyne Array Receiver Programme B/Auto‐Correlation Spectrometer and Imaging System) to study the molecular inventory and the physical structure of these objects, which span different evolutionary stages and physical environments and to probe their evolution during the star formation process. As its name suggests, the SLS will provide a lasting data legacy from the JCMT that is intended to benefit the entire astronomical community. As such, the entire data set (including calibrated spectral data cubes, maps of molecular emission, line identifications, and calculations of the gas temperature and column density) will be publicly available.
NGC 1097 is a nearby SBb galaxy with a Seyfert nucleus and a bright starburst ring. We study the physical properties of the interstellar medium (ISM) in the ring using spatially resolved far-infrared ...spectral maps of the circumnuclear starburst ring of NGC 1097, obtained with the PACS spectrometer on board the Herschel Space Observatory. In particular, we map the important ISM cooling and diagnostic emission lines of OI 63 μm, OIII 88 μm, NII 122 μm, CII 158 μm and NII 205 μm. We observe that in the OI 63 μm, OIII 88 μm, and NII 122 μm line maps, the emission is enhanced in clumps along the NE part of the ring. We observe evidence of rapid rotation in the circumnuclear ring, with a rotation velocity of ~220 km s-1 (inclination uncorrected) measured in all lines. The OI 63 μm/CII 158 μm ratio varies smoothly throughout the central region, and is enhanced on the northeastern part of the ring, which may indicate a stronger radiation field. This enhancement coincides with peaks in the OI 63 μm and OIII 88 μm maps. Variations of the NII 122 μm/NII 205 μm ratio correspond to a range in the ionized gas density between 150 and 400 cm-3.
Abstract We present the largest optical photometry compilation of Gamma-Ray Bursts (GRBs) with redshifts (z). We include 64813 observations of 535 events (including upper limits) from 28 February ...1997 to 18 August 2023. We also present a user-friendly web tool grbLC which allows users to visualise photometry, coordinates, redshift, host galaxy extinction, and spectral indices for each event in our database. Furthermore, we have added a Gamma-ray Coordinate Network (GCN) scraper that can be used to collect data by gathering magnitudes from the GCNs. The web tool also includes a package for uniformly investigating colour evolution. We compute the optical spectral indices for 138 GRBs, for which we have at least 4 filters at the same epoch in our sample, and craft a procedure to distinguish between GRBs with and without colour evolution. By providing a uniform format and repository for the optical catalogue, this web-based archive is the first step towards unifying several community efforts to gather the photometric information for all GRBs with known redshifts. This catalogue will enable population studies by providing light curves (LCs) with better coverage since we have gathered data from different ground-based locations. Consequently, these LCs can be used to train future LC reconstructions for an extended inference of the redshift. The data gathering also allows us to fill some of the orbital gaps from Swift in crucial points of the LCs, e.g., at the end of the plateau emission or where a jet break is identified.
Bulk outflow or global expansion velocities are presented for a large number of planetary nebulae (PNe) that span a wide range of evolutionary stages and different stellar populations. The sample ...comprises 133 PNe from the Galactic bulge, 100 mature and highly evolved PNe from the disk, 11 PNe from the Galactic halo and 15 PNe with very low central star masses and low metallicities, for a total of 259 PNe. These results reveal from a statistical perspective the kinematic evolution of the expansion velocities of PNe in relation to changing characteristics of the central star’s wind and ionizing luminosity and as a function of the evolutionary rate determined by the central (CS) mass. The large number of PNe utilized in this work for each group of PNe under study and the homogeneity of the data provide for the first time a solid benchmark form observations for model predictions, as has been described by López et al. (2016).
We have undertaken echelle spectroscopy and narrow-band line imaging of the bipolar planetary nebula M 1-8. This has permitted us to map the outflow in N iiλλ 6548+6583 Å, Hα, and in thev= 1–0 S(1) ...transition of H2 at λ 2.122 μm. It has also permitted us to acquire high-resolution spectra for N iiλ 6583 Å, Hα and He iiλ 6560 Å. Our observations support the results of a previous 2MASS analysis by two of the authors (J. P. Phillips and G. Ramos-Larios), and confirm that there is strong H2 emission outside of the ionized zone, as well as along the major axis of the outflow. Finally, we have investigated the spatial structure of the outflow in low and high excitation lines, and noted evidence for strong ionization stratification within the envelope of the source. We also note that major axis spectra show asymmetries attributable to outflow along the lobes, oriented at an anglei∼ 35°–40° to the line of sight. Asymmetries along the minor axis, by contrast, appear to be associated with the central collimating disc, and may be interpretable in terms of asymmetries in disc structure, or rotation at an angular velocity of Ω∼ 1.4 10−12 rad s−1. If the disc arises due to common-envelope evolution, then it seems that angular momentum constraints must be relatively tight, and can only be satisfied given fairly extreme physical assumptions (such as low disc mass, high primary star mass, a low distance to the source and so forth).
Progesterone receptors (PR) are present in two isoforms, PR-A and PR-B. The B-upstream segment (BUS) of PR-B is a 164 amino acid N-terminal extension that is missing in PR-A and is responsible for ...the functional differences reported between the two isoforms. BUS contains an activation function (AF3) which is defined by a core domain between residues 54–154 whose activity is dependent upon a single Trp residue and two LXXLL motifs. We have also identified sites both within and outside of BUS that repress the strong synergism between AF3 and AF1 in the N-terminal region and AF2 in the hormone binding domain. One of these repressor sites is a consensus binding motif for the small ubiquitin-like modifier protein, SUMO-1 (
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). The DNA binding domain (DBD) structure is also important for function. When BUS is linked to the glucocorticoid receptor DBD, AF3 activity is substantially attenuated, suggesting that binding to a DNA response element results in allosteric communication between the DBD and N-terminal functional regions. Lastly, biochemical and biophysical analyses of highly purified PR-B and PR-A N-terminal regions reveal that they are unstructured unless the DBD is present. Thus, the DBD stabilizes N-terminal structure. We propose a model in which the DBD through DNA binding, and BUS through protein–protein interactions, stabilize active receptor conformers within an ensemble distribution of active and inactive conformational states. This would explain why PR-B are stronger transactivators than PR-A.
ABSTRACT We present optical and near-infrared (NIR) light curves and optical spectra of SN 2013dx, associated with the nearby (redshift 0.145) gamma-ray burst GRB 130702A. The prompt isotropic ...gamma-ray energy released from GRB 130702A is measured to be erg (1 keV to 10 MeV in the rest frame), placing it intermediate between low-luminosity GRBs like GRB 980425/SN 1998bw and the broader cosmological population. We compare the observed light curves of SN 2013dx to a SN 1998bw template, finding that SN 2013dx evolves ∼20% faster (steeper rise time), with a comparable peak luminosity. Spectroscopically, SN 2013dx resembles other broad-lined SNe Ic, both associated with (SN 2006aj and SN 1998bw) and lacking (SN 1997ef, SN 2007I, and SN 2010ah) gamma-ray emission, with photospheric velocities around peak of ∼ 21,000 km s−1. We construct a quasi-bolometric ( ) light curve for SN 2013dx, only the fifth GRB-associated SN with extensive NIR coverage and the third with a bolometric light curve extending beyond . Together with the measured photospheric velocity, we derive basic explosion parameters using simple analytic models. We infer a 56Ni mass of , an ejecta mass of , and a kinetic energy of erg (statistical uncertainties only), consistent with previous GRB-associated supernovae. When considering the ensemble population of GRB-associated supernovae, we find no correlation between the mass of synthesized 56Ni and high-energy properties, despite clear predictions from numerical simulations that should correlate with the degree of asymmetry. On the other hand, clearly correlates with the kinetic energy of the supernova ejecta across a wide range of core-collapse events.