Victor Rios grew up in the ghetto of Oakland, California in the 1980s and 90s. A former gang member and juvenile delinquent, Rios managed to escape the bleak outcome of many of his friends and earned ...a PhD at Berkeley and returned to his hometown to study how inner city young Latino and African American boys develop their sense of self in the midst of crime and intense policing.Punishedexamines the difficult lives of these young men, who now face punitive policies in their schools, communities, and a world where they are constantly policed and stigmatized.
Rios followed a group of forty delinquent Black and Latino boys for three years. These boys found themselves in a vicious cycle, caught in a spiral of punishment and incarceration as they were harassed, profiled, watched, and disciplined at young ages, even before they had committed any crimes, eventually leading many of them to fulfill the destiny expected of them. But beyond a fatalistic account of these marginalized young men, Rios finds that the very system that criminalizes them and limits their opportunities, sparks resistance and a raised consciousness that motivates some to transform their lives and become productive citizens. Ultimately, he argues that by understanding the lives of the young men who are criminalized and pipelined through the criminal justice system, we can begin to develop empathic solutions which support these young men in their development and to eliminate the culture of punishment that has become an overbearing part of their everyday lives.
Cardiovascular diseases and oxidative stress are related to polycystic ovary syndrome (PCOS) and insulin resistance (IR). We have evaluated the relationship between myeloperoxidase (MPO) and ...leukocyte activation in PCOS patients according to homeostatic model assessment of IR (HOMA-IR), and have explored a possible correlation between these factors and endocrine and inflammatory parameters. This was a prospective controlled study conducted in an academic medical center. The study population consisted of 101 PCOS subjects and 105 control subjects. We divided PCOS subjects into PCOS non-IR (HOMA-IR<2.5) and PCOS IR (HOMA-IR>2.5). Metabolic and anthropometric parameters, total and mitochondrial reactive oxygen species (ROS) production, MPO levels, interactions between human umbilical vein endothelial cells and leukocytes, adhesion molecules (E-selectin, ICAM-1 and VCAM-1) and proinflammatory cytokines (IL-6 and TNF-α) were evaluated. Oxidative stress was observed in PCOS patients, in whom there was an increase in total and mitochondrial ROS production and MPO levels. Enhanced rolling flux and adhesion, and a decrease in polymorphonuclear cell rolling velocity were also detected in PCOS subjects. Increases in IL-6 and TNF-α and adhesion molecules (E-selectin, ICAM-1 and VCAM-1) were also observed, particularly in the PCOS IR group, providing evidence that inflammation and oxidative stress are related in PCOS patients. HOMA-IR was positively correlated with hsCRP (p<0.001, r = 0.304), ROS production (p<0.01, r = 0.593), leukocyte rolling flux (p<0.05, r = 0.446), E-selectin (p<0.01, r = 0.436) and IL-6 (p<0.001, r = 0.443). The results show an increase in the rate of ROS and MPO levels in PCOS patients in general, and particularly in those with IR. Inflammation in PCOS induces leukocyte-endothelium interactions and a simultaneous increase in IL-6, TNF-α, E-selectin, ICAM-1 and VCAM-1. These conditions are aggravated by the presence of IR.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Mano Suave–Mano Dura Rios, Victor M.; Prieto, Greg; Ibarra, Jonathan M.
American sociological review,
02/2020, Letnik:
85, Številka:
1
Journal Article
Recenzirano
Stop-and-frisk and other punitive policing practices disproportionately affect marginalized communities of color. In response to calls for reform, police departments have implemented community ...policing programs aimed at improving relations with racialized communities. This study examines how a police unit used courtesy and respect in its engagement with a criminalized population, gang-associated Latinos, while relying on the stop-and-frisk practice. Our study reveals contextual and situational contradictions between modern police departments’ attempts to establish legitimacy and the hegemonic practice of investigatory stops. Drawing on observations and interviews conducted during a ride-along study, we find that stop-and-frisk, simultaneously used with reform practices like courtesy policing, yield a paradoxical policing approach, “the legitimacy policing continuum.” Officers regularly articulate a goal of respectfully interacting with courtesy to build community and trust—what we term “the mano suave”—while practicing a dominant logic of crime prevention through punitive measures—what we term “the mano dura.” We argue that community and courtesy policing are drawn on strategically in interaction and ultimately intertwined with and constrained by the racial bias at the heart of punitive policing practices like stop-andfrisk.
Worldwide, bacterial resistance to chemical antibiotics has reached such a high level that endangers public health. Presently, the adoption of alternative strategies that promote the elimination of ...resistant microbial strains from the environment is of utmost importance. This review discusses and analyses several (potential) alternative strategies to current chemical antibiotics. Bacteriophage (or phage) therapy, although not new, makes use of strictly lytic phage particles as an alternative, or a complement, in the antimicrobial treatment of bacterial infections. It is being rediscovered as a safe method, because these biological entities devoid of any metabolic machinery do not possess any affinity whatsoever to eukaryotic cells. Lysin therapy is also recognized as an innovative antimicrobial therapeutic option, since the topical administration of preparations containing purified recombinant lysins with amounts in the order of nanograms, in infections caused by Gram-positive bacteria, demonstrated a high therapeutic potential by causing immediate lysis of the target bacterial cells. Additionally, this therapy exhibits the potential to act synergistically when combined with certain chemical antibiotics already available on the market. Another potential alternative antimicrobial therapy is based on the use of antimicrobial peptides (AMPs), amphiphilic polypeptides that cause disruption of the bacterial membrane and can be used in the treatment of bacterial, fungal and viral infections, in the prevention of biofilm formation, and as antitumoral agents. Interestingly, bacteriocins are a common strategy of bacterial defense against other bacterial agents, eliminating the potential opponents of the former and increasing the number of available nutrients in the environment for their own growth. They can be applied in the food industry as biopreservatives and as probiotics, and also in fighting multi-resistant bacterial strains. The use of antibacterial antibodies promises to be extremely safe and effective. Additionally, vaccination emerges as one of the most promising preventive strategies. All these will be tackled in detail in this review paper.
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•Crude sericin extracts of Bombyx mori silk cocoons were produced via two approaches.•Sericin exhibited antioxidant and antimicrobial activities.•The crude sericin extracts had ...obvious radical scavenging effects with DPPH assay.•No cytotoxic, genotoxic and mutagenic effects whatsoever were found.•Sericin might be a valuable addition for food and biopharmaceutical applications.
In the present research effort, production of crude sericin extracts from Bombyx mori silk cocoons was attempted using two different approaches. Sericin was extracted from cocoons by high-temperature autoclaving followed either by lyophilization or freezing-thawing precipitation, to obtain a crude sericin powder. The physico-chemical and biological characteristics of the crude sericin extracts were evaluated in detail, via FTIR, XRD, XRF, XRT, UV–vis scanning, TGA and DSC, protein quantification, antimicrobial activity, free radical scavenging activity, cytotoxic activity, potential for inducing chromosomal aberrations via Allium cepa assays, and genotoxicity via Comet™ analyses. The molecular weight distribution of the crude sericin extracts was also investigated, via sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE), and the results duly compared to standard sericin. The results gathered clearly suggest that the crude sericin extracts had both obvious radical scavenging effects with the 2.2-diphenyl-1-picryl-hydrazil (DPPH) assay, and antibacterial activity, further suggesting that this protein might be a valuable addition for either food and biopharmaceutical applications.
This review discusses contemporary developments in qualitative research on race, crime, and criminal justice, focusing on ethnographic studies of race and policing, criminal justice, prisons, and ...mass incarceration. These ethnographies inform us about the day-to-day contexts in which crime, law, and punishment are produced. They help to make visible structures of power that contribute to inequality, push for a more reflexive approach to ethnography, and sophisticate our understanding of culture. A methodological paradigm has emerged that informs the research process and helps us understand the root causes and consequences of some of the most pressing issues in the United States: race and racism in the justice system, police harassment, police violence, police-community relations, antiauthoritarian social movements, crime prevention, and reentry. This body of scholarship is collectively developing a more reflexive paradigm in ethnography, which we term the sociological double-consciousness approach.
Disturbance by small mammals and shrub canopies are ecological factors typical of arid ecosystems that may influence plant invasion through environmental and community changes. Whereas disturbance ...beneath shrub canopies may promote invasion by removing dominant species, disturbance in open areas may hinder plant invasion by increasing environmental harshness. However, we are unaware of studies explicitly addressing the interactive effects of disturbance by mammals and shading by shrubs on community assembly processes to understand plant invasion. In an arid shrubland, disturbance and shading were caused by the fossorial rodent Spalacopus cyanus and the shrub Flourensia thurifera, respectively. We used functional dispersion data (trait convergence vs. divergence) and Grime´s theory (competitive, stress‐tolerant and ruderal strategies, CSR) to gain insights into the underlying assembly processes.
We compared environmental conditions, richness and abundance of native and exotic species, as well as functional dispersion and prevalence of CSR‐strategies across four microsites (60 × 60 cm plots): undisturbed/open, undisturbed/shaded, disturbed/open and disturbed/shaded. We tested for functional differences between native and exotic species.
Species richness was similar among microsites for both native and exotic species. Shading ameliorated environmental conditions, promoted trait divergence and increased prevalence of C‐ and R‐strategies. Disturbance increased the abundance of exotic species and removed dominant species in shaded microsites. Exotic and native species were functionally different: exotics showed shorter life span, lower height, thinner stems and smaller leaves than natives.
Synthesis. Disturbance, by removing plant biomass, favoured exotic species in shaded microsites, where shrub canopy ameliorated environmental conditions and—by relaxing habitat filtering—promoted niche partitioning processes as well as C‐ and R‐strategies. We illustrate the value of linking trait‐based ecology approaches to micro‐environmental conditions, as it may provide insights into the underlying community processes when studying plant invasions at the local and microsite scales. Disturbed microsites beneath shrub canopies could be ‘hotspots’ where to concentrate efforts to manage plant invasions in arid ecosystems.
Disturbance, by removing plant biomass, favoured exotic species in shaded microsites, where shrub canopy ameliorated environmental conditions and—by relaxing habitat filtering—promoted niche partitioning processes as well as C‐ and R‐strategies. We illustrate the value of linking trait‐based ecology approaches to micro‐environmental conditions, as it may provide insights into the underlying community processes when studying plant invasions at the local and microsite scales. Disturbed microsites beneath shrub canopies could be ‘hotspots’ where to concentrate efforts to manage plant invasions in arid ecosystems.
A paradox exists between capital accumulation and corporate philanthropy: a record number of 'generous' donations and historic levels of social inequality. In education, tech companies are directing ...significant investments to shape public schools. Many efforts to support Latino boys are aligned with these goals, as interventions aim to prepare students for the 'new economy.' Few studies consider the experiences of high-performing Latino boys in relation to tech companies. This paper examines how the Bay Area tech industry, gentrification, and displacement impact the lives of high-performing Latino boys. We draw from an ethnographic study conducted by the first author in the Bay Area of Northern California. This paper shows the way students develop an understanding and actively protest their racialized predicament (i.e. resistance logics), while learning skills to acquire jobs in the tech economy that often appears to perpetuate this racialization (i.e. market logics).
Research: The goal of this study is to understand the experiences of Black and Latino former high school students who dropped out, or were pushed out, of a large urban school district in Southern ...California. Specifically, this paper examines the barriers students faced that contributed to them leaving high school and their journey afterward. Thirty-nine former high school students who “dropped out”, or were pushed out of school, 61.5% males (n = 24) and 38.5% females (n = 15), were interviewed. Findings: The findings indicate the use of punitive truancy control for dealing with health and psychological needs of students, transportation issues, personnel–student relationships, and standardized testing. Examining the experiences of students who have been pushed out of school can help educators and policy makers address some of the inequities within schools. Results: We argue that pushout prevention can be developed by changing truancy and other discipline policies in schools. Implications from this study help us understand how we can better support students before they are pushed out.
Phenotypic plasticity can increase the extent of the environmental gradient occupied by a species (niche breadth) and modify the portion of niche space shared among co‐occurring species (niche ...overlap). Thus, phenotypic plasticity may play a role in community assembly processes. Given that plants deal with a multivariate environment, and that functional traits are often correlated, plastic responses to different environmental factors are likely correlated. However, the implications of correlations of plasticities for niche overlap remain unexplored. Here, we present and evaluate a conceptual framework that links correlations of plasticities and niche overlap patterns among co‐occurring plant species. We specifically tested in an arid shrubland whether positive, negative, or null correlations between plasticity to light and water availability would be associated with patterns of high, low, or random niche overlap, respectively. Field data identified light and water availability as key factors shaping herbaceous plant community structure. We estimated species' niche breadth and niche overlap using two‐dimensional kernel–density estimations (NOK) and standardised effect sizes of Pianka's niche overlap index (OSES). We measured phenotypic plasticity to light and water availability in the six most abundant species in a greenhouse experiment. We used the plasticity index (PI) to test 1) the relationship between plasticity to light and water availability, and 2) the association between overall plasticity (average PI across traits) and niche breadth. We found a positive relationship between plasticity to light and water availability. Increased overall plasticity was associated with a broader niche breadth. Both NOK and OSES estimations indicated a significant niche overlap pattern. Results supported one of the predictions of our conceptual framework: that a positive correlation of plasticities would lead to increased niche overlap. The verified conceptual framework broadens our understanding of the role of phenotypic plasticity in plant community coexistence.
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