Lactobacillus spp. es un género de bacterias gram-positivas que suelen ser consideradas parte de la flora bacteriana normal del ser humano; sin embargo, existe debate de la significancia patológica ...en algunas situaciones. El caso clínico trata de una paciente femenina de 38 años, con el antecedente de consumo de probióticos durante 6 meses, que posterior a la colocación de un balón intragástrico presenta como complicación sangrado digestivo debido a gastritis erosiva y ulceración gástrica difusa y una bronconeumonía asociada a empiema por Lacticaseibacillus rhamnosus. Las infecciones por los gérmenes del género Lactobacillus spp. son infrecuentes y su aislamiento en tejidos o fluidos biológicos estériles debe ser interpretado con cautela según los hallazgos clínicos. La esofagogastroduodenoscopía puede predisponer al desarrollo de neumonía y empiema mediante aspiración; además, se ha visto que el consumo habitual de probióticos aumenta sustancialmente el riesgo de infección por estos gérmenes.
Cryptojacking or illegal mining is a form of malware that hides in the victim's computer and takes the computational resources to extract cryptocurrencies in favor of the attacker. It generates ...significant computational consumption, reducing the computational efficiency of the victim's computer. This attack has increased due to the rise of cryptocurrencies and their profitability and its difficult detection by the user. The identification and blocking of this type of malware have become an aspect of research related to cryptocurrencies and blockchain technology; in the literature, some machine learning and deep learning techniques are presented, but they are still susceptible to improvement. In this work, we explore multiple Machine Learning classification models for detecting cryptojacking on websites, such as Logistic Regression, Decision Tree, Random Forest, Gradient Boosting Classifier,
-Nearest Neighbor, and XGBoost. To this end, we make use of a dataset, composed of network and host features' samples, to which we apply various feature selection methods such as those based on statistical methods, e.g., Test Anova, and other methods as Wrappers, not only to reduce the complexity of the built models but also to discover the features with the greatest predictive power. Our results suggest that simple models such as Logistic Regression, Decision Tree, Random Forest, Gradient Boosting, and
-Nearest Neighbor models, can achieve success rate similar to or greater than that of advanced algorithms such as XGBoost and even those of other works based on Deep Learning.
To evaluate the effects of a chemical restraint with isoflurane compared to a physical restraint in hemogram values in psittacines.
21 adult lilac-crowned parrots (Amazona finschi).
Subjects were ...physically restrained for blood sample collection, after this isoflurane anesthesia was administered for 30 minutes at which time a second blood sample was taken. Hemogram values were compared between both samples using a t test in variables with normal distribution and a Wilcoxon test in variables without normal distribution. Statistical significance was established at P < .05.
When comparing the analytes of the respective CBCs, a decrease in PCV (P < .001), RBC count (P < .001), WBC count (P = .017), absolute lymphocytes (P = .024), and total proteins (P < .001) was observed in the samples taken under chemical restraint. No significant differences in MCV and absolute values of heterophils, monocytes, or eosinophils were observed.
Isoflurane causes a decrease in some blood count values in lilac-crowned parrots under isoflurane anesthesia for 30 minutes. Although the magnitude of change could be variable between values, it is important to consider the blood collection method when interpreting the blood count in this species.
Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-wide variation from this region remain largely uncharacterized. We studied genomic variation within Mexico ...from over 1000 individuals representing 20 indigenous and 11 mestizo populations. We found striking genetic stratification among indigenous populations within Mexico at varying degrees of geographic isolation. Some groups were as differentiated as Europeans are from East Asians. Pre-Columbian genetic substructure is recapitulated in the indigenous ancestry of admixed mestizo individuals across the country. Furthermore, two independently phenotyped cohorts of Mexicans and Mexican Americans showed a significant association between subcontinental ancestry and lung function. Thus, accounting for fine-scale ancestry patterns is critical for medical and population genetic studies within Mexico, in Mexican-descent populations, and likely in many other populations worldwide.
The reaction of 2,5‐dibromopyrazine with N‐Lithium pyrazolate in a 1:2 ratio leads to a mixture of 2‐bromo‐5‐(1H‐pyrazol‐1‐yl)pyrazine (I) and 2,5‐di(1H‐pyrazol‐1‐yl)pyrazine (II). The structures of ...I and II are highly planar. Two absorption bands can be observed for the compounds in the UV‐Vis region, having ε in the order of 104 m−1 cm−1. TD‐DFT computed results support the nature of the lower energy absorptions as πpyrazine→π*pyrazine transitions, including an additional intraligand charge transfer transition for I (πpyrazol→π*pyrazine). Upon excitation at 280 or 320 nm, the emission of both compounds is almost not affected by solvent polarity or oxygen presence, showing two bands for I and one for II in the 350–450 nm region. Emission of II follows a mono‐exponential decay, while I decays following a bi‐exponential law, hypothesized from πpyrazine→π*pyrazine and πpyrazol→π*pyrazine transitions. Photodegradation of I and II follows a first‐order kinetic with constants of 1.18 × 10−2 min−1 and 0.13 × 10−2 min−1, respectively. Results suggest that photodegradation of I starts with the loose of bromide followed by intermolecular pyrazolyl subtraction and ring opening. This path is not available for II, which is reflected in its enhanced photostability.
The photophysical and photochemical properties of 2,5‐pyrazine derivatives are modulated depending on the presence of pyrazolyl substituents. Two rigid pyrazolyl‐pyrazine were synthesized: 2‐bromo‐5‐(1H‐pyrazol‐1‐yl)pyrazine (I) and 2,5‐di(1H‐pyrazol‐1‐yl)pyrazine (II). The molecular structures of both compounds are highly planar. Both molecules define ribbons in the solid state by means of nonclassical C—H···N hydrogen bonds, in zigzag for I and planar for II. Photodegradation of I starts with the loose of bromide. This path is not available for II, resulting in an enhanced photostability.
Data Mining for Education is an emerging discipline which seeks to develop methods to explore large amounts of data from educational settings, in order to understand students better. In recent years ...there have been various works related with this specialty and have used multiple data mining techniques derived from this to address different educational problems. The aim of this publication is to present a review of the works in which data mining techniques were used to solve specific problems of education and to do a classification of these, associated with diverse scenarios in which it has been applied.
Remote sensing and traditional ecological knowledge (TEK) can be combined to advance conservation of remote tropical regions, e.g. Amazonia, where intensive in situ surveys are often not possible. ...Integrating TEK into monitoring and management of these areas allows for community participation, as well as for offering novel insights into sustainable resource use. In this study, we developed a 250 m resolution land-cover map of the Western Guyana Shield (Venezuela) based on remote sensing, and used TEK to validate its relevance for indigenous livelihoods and land uses. We first employed a hyper-temporal remotely sensed vegetation index to derive a land classification system. During a 1 300 km, eight day fluvial expedition in roadless areas in the Amazonas State (Venezuela), we visited six indigenous communities who provided geo-referenced data on hunting, fishing and farming activities. We overlaid these TEK data onto the land classification map, to link land classes with indigenous use. We characterized land classes using patterns of greenness temporal change and topo-hydrological information, and proposed 12 land-cover types, grouped into five main landscapes: 1) water bodies; 2) open lands/forest edges; 3) evergreen forests; 4) submontane semideciduous forests, and 5) cloud forests. Each land cover class was identified with a pulsating profile describing temporal changes in greenness, hence we labelled our map as "The Forest Pulse". These greenness profiles showed a slightly increasing trend, for the period 2000 to 2009, in the land classes representing grassland and scrubland, and a slightly decreasing trend in the classes representing forests. This finding is consistent with a gain in carbon in grassland as a consequence of climate warming, and also with some loss of vegetation in the forests. Thus, our classification shows potential to assess future effects of climate change on landscape. Several classes were significantly connected with agriculture, fishing, overall hunting, and more specifically the hunting of primates, Mazama americana, Dasyprocta fuliginosa, and Tayassu pecari. Our results showed that TEK-based approaches can serve as a basis for validating the livelihood relevance of landscapes in high-value conservation areas, which can form the basis for furthering the management of natural resources in these regions.
Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-wide variation from this region remain largely uncharacterized. We studied genomic variation within Mexico ...from over 1000 individuals representing 20 indigenous and 11 mestizo populations. We found striking genetic stratification among indigenous populations within Mexico at varying degrees of geographic isolation. Some groups were as differentiated as Europeans are from East Asians. Pre-Columbian genetic substructure is recapitulated in the indigenous ancestry of admixed mestizo individuals across the country. Furthermore, two independently phenotyped cohorts of Mexicans and Mexican Americans showed a significant association between subcontinental ancestry and lung function. Thus, accounting for fine-scale ancestry patterns is critical for medical and population genetic studies within Mexico, in Mexican-descent populations, and likely in many other populations worldwide.