The article considers the method of planning the production capacity of a high-tech enterprise based on the application of the Pontryagin maximum mathematical model. The presented method is aimed at ...increasing the productivity of the equipment installed at the enterprise, in order to optimize the time spent and the volume of products produced. The study analyses the activities of research and production enterprise in order to improve the level of efficiency of production capacity management. The purpose of the research is to organize an effective process of planning production capacities of a high-tech enterprise based on the application of the Pontryagin maximum mathematical model, which allows you significantly to increase not only equipment performance indicators, but also optimize the time required to complete the current production program. The author tested the algorithms, models and methods proposed in the article at a research and production enterprise engaged in the production of high-tech products. The use of the obtained models will allow you to optimize peak loads in the current production program at the enterprise, reduce the labor intensity indicators in the annual production plan, determine the necessary amount of production equipment, which will eventually reduce the amount of necessary investments. The paper gives a practical example of the organization of a new type of production aimed at manufacturing various parts of complex shape.
Gut microbiota of patients with Parkinson’s disease and healthy volunteers was analyzed by the method of high throughput 16S rRNA sequencing of bacterial genomes. In patients with Parkinson’s ...diseases, changes in the content of 9 genera and 15 species of microorganisms were revealed: reduced content of
Dorea
,
Bacteroides
,
Prevotella
,
Faecalibacterium
,
Bacteroides massiliensis
,
Stoquefichus massiliensis
,
Bacteroides coprocola
,
Blautia glucerasea
,
Dorea longicatena
,
Bacteroides dorei
,
Bacteroides plebeus
,
Prevotella copri
,
Coprococcus eutactus
, and
Ruminococcus callidus
, and increased content of
Christensenella
,
Catabacter
,
Lactobacillus
,
Oscillospira
,
Bifidobacterium
,
Christensenella minuta
,
Catabacter hongkongensis
,
Lactobacillus mucosae
,
Ruminococcus bromii
, and
Papillibacter cinnamivorans
. This microbiological pattern of gut microflora can trigger local inflammation followed by aggregation of α-synuclein and generation of Lewy bodies.
The article is devoted to the study of the main methods of evaluating the effectiveness of activities in the field of public relations. The paper indicates the main features that characterize modern ...PR technologies: innovation, manufacturability, consistency, the guarantee of certain practical results, and so on. Public relations are currently one of the fastest-growing components of the marketing communications complex, which is aimed at forming and strengthening a positive image of the company in the eyes of public groups. The study ascertains that to calculate the effect of PR campaigns and return on investment (ROI), it is necessary to use the construction of special multicomponent correlation models, where media analytical indicators can be correlated with certain financial results. The author considers the metric of the use value norm used to assess the current level and effectiveness of the company’s communication policy, taking into account the complex of various PR activities. The study gives an algorithm for finding an effective commercial offer in the B2B segment. The paper creates a formula that allows calculating the socio-economic efficiency of a PR company. In conclusion of the article, the author presents groups of indicators that should be paid attention to by the company’s top management to evaluate conducted PR campaign.
The technique for the development of modern economic systems, taking into account the influence of various groups of innovative factors has been created. The structural elements of the innovative ...economy, the features of the stability of modern economic systems have been revealed and also the main types of stability and ways to improve it have been determined. The object of study are multicomponent economic systems – industrial enterprises that are directly affected by various innovative factors of development. The method that allows you effectively implement various processes of planning and innovative development at high-tech enterprises in modern economic conditions have been proposed. The main indicators of the forecast of social, economic and innovative development of Russia from 2018 to 2020 have been presented. The problems that exist in the organization of public-private partnership have been considered.
The article is devoted to the analysis of the digital transformation of machine-building complex enterprises. In the theoretical part it is determined that the development is possible due to the ...effective and qualitative renewal of existing production and business processes on the basis of comprehensive introduction of advanced innovations. There are key business objectives of the technological concept «Industry 4.0» in the article. There are also factors influencing the indicators of competitiveness of Russia in the implementation of the concept of technological breakthrough. In the research part of the article the influence of digitalization processes on the competitiveness of products in the digital production is determined. The «roadmap» is made in accordance with the provisions of the program «Digital economy of the Russian Federation» and «Digital engineering». As a result of the analysis, it was determined that in the developed program, the main importance, of course, is the development of special standards necessary for the qualitative development of the digital architecture of the enterprise. In conclusion, the authors shown that it is necessary to have certain competencies of employees working at the enterprise, as well as the management should understand the growing need to create new jobs for highly qualified specialists processing and analyzing production information within the production enterprise for a competent digital transformation.
A mathematical model has been developed for the radiolysis of an aqueous solution containing the VVER primary coolant components ammonia and boric acid. The test results show that the average ...deviation of the model calculation results from experimental data does not exceed 35% when processing about 250 experimental data points. This model correctly predicts the temporal evolution of the VVER coolant quality indicators (concentrations of H
2
, O
2
, and NH
3
) and can be used to analyze their behavior at various parameters of the VVER core (temperature, power, boron content, etc.).
Based on Schumpeter’s process of creative destruction, we propose a qualitative model of the cyclic process of introducing new technologies. The model consists of a variable structure system with ...switchings between three globally stable dynamical subsystems. The switchings between regimes make it possible to describe the process of departing the system from the equilibrium state in the process of introducing new technologies. The alternation of regimes implies lack of equilibrium for the variable structure system despite the global stability of its subsystems. This mathematical fact corresponds to a typical situation in real economic systems during the renovation period. The proposed model shows the global cyclicity of the process of introducing new technologies. In the case of an unsuccessful technology introduction, we establish the existence of a closed trajectory of the system.
The results of simulation of radiation-chemical transformations in the primary coolant of a water-cooled water-moderated energy reactor (VVER) are presented. It has been shown that under conditions ...of intense irradiation, molecular nitrogen dissolved in the coolant exhibits chemical activity. The reaction of N
2
with the excited hydroxyl radical initiates the formation of ammonia and nitrous acid. Further decomposition of ammonia produces only oxidized forms of nitrogen, with N
2
acting as an intermediate product. Maintaining hydrogen and oxygen concentrations within normal limits in the ammonia water chemistry is possible only with constant dosing of NH
3
and degassing of the coolant. In the case of water chemistry with H
2
dosing (at the initial moment), on the contrary, a stationary regime is quickly established in the absence of disturbances, satisfying the requirements of VVER water chemistry standards. The difference between the two water chemistry systems is due to the presence of nitrogen in the NH
3
molecule and its transformations as an element, regardless of the initial chemical form.
Interference of wave trains separated out in an inhomogeneous emission spectrum of a superluminescent erbium-doped fibre source has been studied by scanning the wavelength of a spectrum analyser. The ...results demonstrate that, as the spectral resolution of the spectrum analyser decreases to a level corresponding to a sharp drop in interference fringe visibility relative to its original level, near 100 %, fringe visibility becomes dependent on the wavelength in the inhomogeneous spectrum of the source. The reason for this is that, at some characteristic resolution δλ (δλ > 0.5 nm in our case), the coherence time of wave trains is not limited by the spectral resolution of the spectrum analyser and is related to the inhomogeneous spectrum of the source, whose limiting width can be thought of as the homogeneous linewidth in the spectrum of the source. This feature can be used for evaluating homogeneous line broadening.
The fungal component of the microbiome associated with the six-toothed bark beetle
Ips sexdentatus
(Börner, 1776) in the territory of Belarus was studied in order to clarify the role of this ...xylophage as a vector of dangerous phytopathogenic fungi. More than 360 pure fungal cultures isolated from the surface and hemocoel of
I. sexdentatus
were analyzed by morphological and molecular genetic methods, and 35 species from 25 genera, 17 families, and 3 divisions of fungi were identified. All these species were conventionally classified into three groups based on their impact on wood: (1) fungi that cause wood discoloration (mold, blue stain, etc.), (2) fungi that cause rot in living trees and cut wood, and (3) fungi whose effect on harvested timber remains unclear. Five species of
Ophiostomataceae
fungi associated with blue rot were identified:
Leptographium
Lagerb. & Melin sp.,
Ophiostoma ips
(Rumbold) Nannf.,
O. minus
(Hedgc.) Syd. & P. Syd.,
O. canum
(Münch) Syd. & P. Syd., and
O. piceae
(Münch) Syd. & P. Syd. The root rot agent
Heterobasidion annosum
(Fr.) Bref. was detected in 7.8% of the studied fungal samples. The fairly high occurrence of
I. sexdentatus
confirms its participation in the development of complex pine dieback foci in Belarus. A considerable level of infection with four species of entomopathogenic fungi (11.4%) was recorded in the
I. sexdentatus
population by molecular genetic methods.
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