The Dawn Framing Camera (FC) acquired almost 900 clear filter images of Ceres with a resolution of about 400m/pixels during the seven cycles in the Survey orbit in June 2015. We ortho-rectified 42 ...images from the third cycle and produced a global, high-resolution, controlled mosaic of Ceres. This global mosaic is the basis for a high-resolution Ceres atlas that consists of 3 tiles mapped at a scale of 1:2,000,000. The nomenclature used in this atlas was proposed by the Dawn team and was approved by the International Astronomical Union (IAU). The whole atlas is available to the public through the Dawn GIS web page http://dawn_gis.dlr.de/atlas.
•The mosaic of Ceres was created using camera data from Survey orbit.•An atlas of Ceres consisting of three tiles was created.•The nomenclature for surface features was approved by the IAU and applied to the atlas.
BackgroundTransvenous catheter ablation of atrioventricular nodal re-entrant tachycardia (AVNRT) with radiofrequency (RF) is effective and safe, but carries a 1–3% incidence of early and potentially ...late heart block. Cryothermy can create transient effects, and identify potentially successful ablation sites and decrease the risk for permanent heart block. Methods In this prospective, randomized trial 102 patients with recurrent narrow QRS-complex tachycardia suggestive of AVNRT were randomized to either RF or cryoablation before a diagnostic study. Results In 63 patients with AVNRT, 33 were randomized to RF and 30 to cryoablation. Procedural success was achieved, respectively, in 30 (91%) patients in the RF and 28 (93%) in the cryoablation group. The median number of cryothermal applications was significantly lower than the number of RF applications (2 versus 7, p<0.005). No accelerated junctional rhythm was seen with cryothermy, while it was present in 31/33 RF patients. Both fluoroscopy and procedural times were comparable. The radiological position of the successful site in relation to anatomical landmarks was slightly different (p<0.05). No cryothermy related complications were observed, and no permanent AV conduction disturbances occurred. During a mean follow up of 13±7 months long-term clinical success was seen in one additional patient in each group. In the same period, 3 patients in both groups experienced recurrent AVNRT. Conclusion Cryoablation is as effective and safe as RF for AVNRT. Significantly fewer applications are necessary, with comparable procedure times. This makes cryothermy useful for the treatment of tachyarrhythmias near the compact AV node.
In line with this, the 2017 Heart Rhythm Society/European Heart Rhythm Association expert consensus statement on catheter and surgical ablation of atrial fibrillation states it is reasonable to use ...an oesophageal temperature probe during ablation procedures to monitor oesophageal temperatures to help guide energy delivery (Class IIa) 5. Luminal oesophageal temperature—guided PVI significantly reduces the incidence of thermal oesophageal lesions 6. ...although lesions cannot always be avoided, they tend to be smaller in patients when using a temperature probe 7. ...the temperature of the oesophageal tissue at risk—situated closest to the posterior wall of the left atrium—is not always sufficiently monitored. ...research and development in this field is necessary to eliminate PVI-related atrio-oesophageal complications.
Interior layered deposits (ILDs) within western Candor Chasma were studied by mapping lithologies, measuring layer attitudes and comparing the stratigraphy of two adjacent mounds. Layering tends to ...dip in the same direction as the local topographic slope, although at different angles. Regionally consistent attitudes do exist, suggesting postdepositional block rotations. The stratigraphy of two adjacent mounds correlates, but the thicknesses of the units differ. Most layered material appears to have been deposited conformably, with one late major unconformity. Several fault populations are identified and correlate well with regional faults associated with the formation of Valles Marineris. The data suggest that here the ILDs predate the faulting and may be early basin fill. According to our model for ILD formation, ILDs are deposited syntectonically during early basin collapse. Subsequent subsidence of surrounding areas, accompanied by little or no sedimentation, left the early deposits as individual mounds, remnants of the former subbasins. Stratigraphic differences between mounds resulted from different subsidence rates of subbasins. A significant change in depositional environment, from depositional to a near cessation of deposition and the onset of a major erosion event, possibly coincided with the opening of the main Valles Marineris troughs. We further suggest that groundwater played an important role in the formation of sulfates. The youngest unit identified, not including surficial deposits, is likely the result of a posttectonic, regionally limited volcanic event. If basin collapse continued following the cessation of deposition, this model can also account for mounds within closed basins, such as Hebes.
The Dawn framing camera (FC) acquired about 2500 clear filter images of Vesta with a resolution of about 70m/pixels during the High Altitude Mapping Orbit (HAMO) in fall 2011. We ortho-rectified ...these images and produced a global high resolution controlled mosaic of Vesta. This global mosaic is the baseline for a high resolution Vesta atlas that consists of 15 tiles mapped at a scale of 1:500,000. The nomenclature used in this atlas was proposed by the Dawn team and was approved by the International Astronomical Union (IAU). The whole atlas is available to the public through the Dawn GIS web page http://dawn_gis.dlr.de/atlas.
► The first controlled high resolution mosaic of Vesta was created using camera data from the high altitude mapping orbit. ► The first atlas of Vesta was created. ► The nomenclature for surface features was approved by the IAU.
To reduce sudden cardiac death, implantable cardioverter-defibrillators (ICDs) are indicated in patients with ischaemic and non-ischaemic dilated cardiomyopathy and a left ventricular ejection ...fraction (LVEF) ≤35%. Current guidelines do not recommend device therapy in patients with a life expectancy <1 year since benefit in these patients is low. In this study, we evaluated the incidence and predictors of early mortality (<1 year after implantation) in a consecutive primary prevention population.
Analysis was performed on a prediction and validation cohort. The primary endpoint was all-cause mortality at 1 year. The prediction cohort comprised 861 prophylactic ICD recipients with ischaemic cardiomyopathy or dilated cardiomyopathy from the Academic Medical Center (Amsterdam) and Thorax Center Twente (Enschede). Detailed clinical data were collected. After multivariate analysis, a risk score was developed based on age ≥75 years, LVEF ≤ 20%, history of atrial fibrillation, and estimated glomerular filtration rate (eGFR) ≤30 mL/min/1.73 m(2). Using these predictors, a low (≤1 factor), intermediate (2 factors), and high (≥3 factors) risk group could be identified with 1-year mortality of, respectively, 3.4, 10.9, and 38.9% (P< 0.01). Afterwards, the risk score was validated in 706 primary prevention patients from the Erasmus Medical Center (Rotterdam). One-year mortality was, respectively, 2.5, 13.2, and 46.3% (all P< 0.01).
A simple risk score based on age, LVEF, eGFR, and atrial fibrillation can identify patients at low, intermediate, and high risk for early mortality after ICD implantation. This may be helpful in the risk assessment of ICD candidates.
Background
Low oesophageal temperatures (OTs) during cryoballoon pulmonary vein isolation (PVI) have been associated with complications. This study assessed the incidence of low OT in clinical ...practice during cryoballoon PVI and verified possible predictive values for low OT.
Methods
Consecutive patients who underwent PVI using the second-generation cryoballoon were retrospectively included. The distance from the oesophagus to the different pulmonary veins (PVs) (OP distance), body mass index (BMI), sex, age, balloon temperature and application time were studied as potential predictors of low OTs. Computed tomography was performed before the procedure to determine the OP distance. OT was measured using an oesophageal temperature probe. Applications were ended prematurely if the OT reached <16 °C. Low and ultralow OT were defined as OT <20 and <16 °C respectively.
Results
Two hundred and four patients were included. Low OT was observed in 54 patients (26%) and 27 patients (13%) reached ultralow OTs. OP distance was the only predictor of low OTs after multivariate analysis. A cut-off value of 19 mm showed 96.2% sensitivity and 37.8% specificity in predicting low OTs. No clinically relevant relation was found between low OTs and BMI, age, sex, balloon temperature or application duration.
Conclusions
The incidence of low OT was 26% for cryoballoon PVI. OP distance was the only predictor of low OTs. Since an OP distance <19 mm was present in all patients in at least one PV, we recommend routine OT measurement during PVI cryoballoon therapy to prevent oesophagus-related complications.
The Dawn Topography Investigation Raymond, C. A.; Jaumann, R.; Nathues, A. ...
Space science reviews,
12/2011, Letnik:
163, Številka:
4-Jan
Journal Article
Recenzirano
Odprti dostop
The objective of the Dawn topography investigation is to derive the detailed shapes of 4 Vesta and 1 Ceres in order to create orthorectified image mosaics for geologic interpretation, as well as to ...study the asteroids' landforms, interior structure, and the processes that have modified their surfaces over geologic time. In this paper we describe our approaches for producing shape models, plans for acquiring the needed image data for Vesta, and the results of a numerical simulation of the Vesta mapping campaign that quantify the expected accuracy of our results. Multi-angle images obtained by Dawn's framing camera will be used to create topographic models with 100 m/pixel horizontal resolution and 10 m height accuracy at Vesta, and 200 m/pixel horizontal resolution and 20 m height accuracy at Ceres. Two different techniques, stereophotogrammetry and stereophotoclinometry, are employed to model the shape; these models will be merged with the asteroidal gravity fields obtained by Dawn to produce geodetically controlled topographic models for each body. The resulting digital topography models, together with the gravity data, will reveal the tectonic, volcanic and impact history of Vesta, and enable co-registration of data sets to determine Vesta's geologic history. At Ceres, the topography will likely reveal much about processes of surface modification as well as the internal structure and evolution of this dwarf planet.
Transcatheter pulmonary vein ablation is the current treatment of choice for symptomatic drug-refractory atrial fibrillation (AF). Video-assisted surgical pulmonary vein isolation (sPVI) is an ...alternative therapy to percutaneous ablation for the treatment of AF. Long-term results of sPVI are currently unknown. The aim of this study was to report on the long-term efficacy and safety of sPVI in patients with paroxysmal AF.
The study design was observational and retrospective. From July 2005 to January 2011, 42 patients with drug-refractory paroxysmal AF underwent video-assisted sPVI in two different centres. Patients were eligible for sPVI when suffering from symptomatic, drug-refractory paroxysmal AF and they agreed to the alternative of sPVI. The median preoperative AF duration was 24 months (range 3-200). Success was defined as the absence of AF on 24 h or 96 h Holter monitoring during follow-up, off antiarrhythmic drugs (AAD). Adverse events and follow-up monitoring were based on the Heart Rhythm Society Consensus Statement 2012 for the catheter and surgical ablation of AF. Mean age was 55 ± 10 years, and 76% were males. After a mean follow-up of 5 years (SD 1.7), 69% of all patients were free from atrial arrhythmias without the use of AAD, and 83% with the use of AAD. Major peri-procedural adverse events occurred in four (9.5%) patients, no strokes or mortalities were registered during long-term follow-up.
This retrospective study shows that sPVI for the treatment of paroxysmal AF is effective and that the outcomes are maintained at long-term follow-up.
•Dark material deposits on Vesta are almost correlated with impact features.•Dark material deposits are isolated patches of less than 100m thickness.•Impacts multiply reworked the dark material ...subsurface layers.•Dark material deposits are closely associated with the Veneneia impact structure.
Deposits of dark material appear on Vesta’s surface as features of relatively low-albedo in the visible wavelength range of Dawn’s camera and spectrometer. Mixed with the regolith and partially excavated by younger impacts, the material is exposed as individual layered outcrops in crater walls or ejecta patches, having been uncovered and broken up by the impact. Dark fans on crater walls and dark deposits on crater floors are the result of gravity-driven mass wasting triggered by steep slopes and impact seismicity. The fact that dark material is mixed with impact ejecta indicates that it has been processed together with the ejected material. Some small craters display continuous dark ejecta similar to lunar dark-halo impact craters, indicating that the impact excavated the material from beneath a higher-albedo surface. The asymmetric distribution of dark material in impact craters and ejecta suggests non-continuous distribution in the local subsurface. Some positive-relief dark edifices appear to be impact-sculpted hills with dark material distributed over the hill slopes. Dark features inside and outside of craters are in some places arranged as linear outcrops along scarps or as dark streaks perpendicular to the local topography. The spectral characteristics of the dark material resemble that of Vesta’s regolith. Dark material is distributed unevenly across Vesta’s surface with clusters of all types of dark material exposures. On a local scale, some craters expose or are associated with dark material, while others in the immediate vicinity do not show evidence for dark material. While the variety of surface exposures of dark material and their different geological correlations with surface features, as well as their uneven distribution, indicate a globally inhomogeneous distribution in the subsurface, the dark material seems to be correlated with the rim and ejecta of the older Veneneia south polar basin structure. The origin of the dark material is still being debated, however, the geological analysis suggests that it is exogenic, from carbon-rich low-velocity impactors, rather than endogenic, from freshly exposed mafic material or melt, exposed or created by impacts.
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