As is well known, there exist some Lorentz breaking scenarios which explain the smallness of the cosmological constant in the present era. An important aspect to analyze is the propagation of ...gravitational waves and the screening or enhancement of the Newton constant \(G_N\) in these models. The problem is that the Lorentz symmetry breaking terms may induce an unacceptable value of the Newton constant \(G_N\) or introduce longitudinal modes in the gravitational waves. Furthermore there may spoil the standard dispersion relation \(\omega=ck\). In 21 the authors have presented a model for which they suggest that the behavior of the gravitational constant is the correct one for asymptotic times. In the present work, an explicit checking is made and we finally agree with these claims. Furthermore, it is suggested that the gravitational waves are also well behaved for large times. In the process, some new models with the same behavior are obtained, thus enlarging the list of possible adjustment mechanisms.
Mutagenicity studies on thymomodulin Cantelli-Forti, G; Hrelia, P; Scotti, M ...
Arzneimittel-Forschung,
11/1987, Letnik:
37, Številka:
11
Journal Article
Thymomodulin (Leucotrofina), an orally administrable thymic derivative endowed with interesting immunomodulating and myelomodulating properties, was tested for mutagenicity by means of the following ...in vitro and in vivo tests: mutagenesis on S. typhimurium with and without metabolic activation system (S-9), gene conversion on S. cerevisiae D 7 with and without metabolic activation, urinary assay in the mouse with and without metabolic activation, urinary assay in the mouse with S. cerevisiae D 7, host mediated assay in the mouse with S. cerevisiae and DNA repair test with and without metabolic activation. On the basis of the results obtained thymomodulin proved to be free of mutagenic activity.
A phase II study of mitoxantrone in advanced breast cancer Pronzato, P; Ardizzoni, A; Conte, P F ...
Chemioterapia : international journal of the Mediterranean Society of Chemotherapy,
06/1986, Letnik:
5, Številka:
3
Journal Article
A phase II study with mitoxantrone has been carried out in 30 metastatic breast cancer patients. Of 26 evaluable patients 7 (26.9%) experienced a partial response; 7 (26.9%) patients had stable ...disease and 12 (46.1%) had progression. Major toxicity observed was: nausea and vomiting in 52% of patients, moderate hair loss in 53% of patients and leukopenia in 53%.
