Globally, antimicrobial resistance (AMR) is a complex public problem, which is mainly fuelled by inappropriate use of antimicrobials. Rational use of antimicrobials is the main strategy for the ...prevention of AMR, which can be achieved by changing the prescribers' behavior and knowledge. Hence, this study aimed to assess knowledge and attitude of paramedical students regarding antimicrobial resistance, which helps to rationalize the use of antimicrobials.
An institutional based cross-sectional study was performed on 323 graduates paramedical students at the University of Gondar, Ethiopia. Participants were invited to complete a self-reported structured questionnaire on hard copy. The data were summarized using summary statistics such as the median. Furthermore, Kruskal Wallis test, at the level of significance of 0.05, was conducted to compare group difference.
Among 360 eligible paramedical students, 323 (90%) of them participated and most of them were males 202 (62.5%). Nearly 96% of the participants perceived that antimicrobial resistance is a catastrophic and preventable public problem but about half of the participants (55%) had a poor level of knowledge. It was also found that there was a statistically significant knowledge and attitude difference across the department (p-value< 0.0001) and (p = 0.002), respectively. Furthermore, those participants who had a good level of knowledge had greater attitude rank as compared to those who had a moderate and poor level of knowledge (p-value< 0.0001).
Majority of the participants viewed antimicrobial resistance as a preventable public problem if appropriate strategies are formulated. Nonetheless, most of them had a poor knowledge regarding antimicrobial resistance, and their knowledge and attitude significantly vary across their field of study. This result implicates that improving the students' level of knowledge about antimicrobial resistance might be an approach to flourish their attitude and to rationalize their antimicrobial use.
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Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Adequate knowledge about the highest conception probability period in the reproductive cycle allows individuals and couples to attain or avoid their fertility probabilities. Poor knowledge of ...conception probability period leads to undesirable outcomes like unwanted pregnancy, miscarriage, and abortion. Determinants of knowledge of highest conception probability period were not well studied on economically disadvantaged countries. Therefore, our study aimed to identify individual and community level factors of knowledge of the highest conception probability period among women of reproductive age in low income African countries.
The appended and latest Demographic and Health Survey datasets of 15 low-income African countries was used for analysis. Model fitness was done using the Intraclass correlation coefficient, median odds ratio, and deviance. A model with the lowest deviance (model-III) was selected as the best model. Multilevel logistic regression model was used to identify determinant factors of knowledge of the highest conception probability period. In the final model, adjusted odds ratio with 95% confidence interval was reported and variables with p<0.05 were considered as statistically significant with knowledge of the highest conception probability period.
Total weighted sample of 235,574 reproductive aged women with a median age of 27 years were included. The correct knowledge of the highest conception probability period among the study participants was 24.04% (95%CI = 23.87-24.22%). Maternal age groups ((20-24 (AOR = 1.49; 95%CI = 1.44-1.55), 25-29 (AOR = 1.62; 1.56-1.68), 35-39 (AOR = 1.76; 1.68-1.84), 40-44 (AOR = 1.75; 1.67-1.83), and 45-49 (AOR = 1.83; 1.74-1.93)), marital status((currently in union (AOR = 1.75; 1.16; 1.13-1.20), formerly in union (AOR = 1.75; 1.11; 1.06-1.16)), better educational status ((secondary (AOR = 2.08; 2.01-2.14) and higher(AOR = 3.36; 3.18-3.55)), higher wealth index ((middle (AOR = 1.08; 1.04-1.12), richer (AOR = 1.24; 1.20-1.28), and richest (AOR = 1.51; 1.45-1.57)), knowledge of contraceptive methods (AOR = 2.63; 2.49-2.77), current contraceptive use (AOR = 1.14; 1.11-1.16), and urban residency (AOR = 1.26; 1.21-1.29) were statistically significant with knowledge of the highest conception probability period.
In this study, knowledge of the highest conception probability period among women of reproductive age in low-income African countries was low. Therefore, improving the fertility awareness through comprehensive reproductive education or counseling could be one of the operational ways to control unintended pregnancy.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Water scarcity is one of the most significant constraints on agricultural production in the world, notably in Ethiopia. In the location where this study was conducted, production is only possible ...once a year. To make the most use of available water, effective water application technologies must be used, and the feasibility of producing crops in water-stressed scenarios must also be researched. In areas of water shortage, deficit irrigation was an essential approach for raising water production and improving water use efficiency. For this purpose, a field experiment was carried out at Alage ATVET College in Ethiopia's Central Rift Valley during the 2019/20 dry season. The regularly grown cash crop pepper was chosen for experimentation under drip irrigation. The study aimed were to investigate the influence of deficit irrigation levels on agronomic performance and water productivity. Seven deficit levels (DI) namely 60, 50, 40, 30, 20, 10 and 0% were laid out in a randomized complete block design with three replications by using drip irrigation. Water application was used in all deficit levels by managing the demand side. Full irrigation produced the maximum plant height, branch number, fruit weight per plant, fruit diameter, fruit length, marketable and total yield. However, at 20% DI levels, stem diameter, flower and fruit number per plant increased. There were only significant variations in total dry yield at 50% and 60% deficiency levels. Marketable yield was significantly different across all deficit levels. It was not possible to determine the water stress threshold level of pepper due to the large variation in yield, but at 30% DI, the yield reduction was about one-quarter of the 0% deficiency level by withholding 33.4% water. CWUE was significantly different at all deficit levels, demonstrating that as stress levels rise, so does CWUE. IWUE exhibited significant difference only at 0 and10% DI. As a result, it is possible to conclude that using at 30% deficit by withholding 33.4% of water can be used to optimize the yield and water productivity of pepper production at Alage and other areas with comparable agro-ecology.
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Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Abstract Background Due to the asymptomatic nature of the disease and lack of awareness, most glaucoma patients present for eye examination late, after significant damage of optic nerve occur. Being ...aware of glaucoma is important for timely diagnosis of the disease and preventing blindness from it. Objective The aim of this study was to assess glaucoma awareness and associated factors among adult patients aged 35 and over attending the eye outpatient department. Methods Hospital based cross-sectional study was conducted on 284 adult patients aged 35 and over attending ophthalmic outpatient department from July to August 2022 using systematic random sampling. An interviewer-administered questionnaire was used to collect data. The data were checked for completeness, and then entered to SPSS version 22 software. Descriptive and binary logistic regression analyses were performed. Independent variables with p -value ≤ 0.05 in multivariate logistic regression were considered as statistically significant. Results About 284 study participants, of whom 57.75% were male, participated in this study with a response rate of 94.1%. The mean age of the study participants was 53.58 years. Only 39.09%(95% CI: 36.53–41.65) were aware of glaucoma. Age groups 46–50 AOR; 1.83: 1.18, 2.56 and 51–64 AOR; 3.21: 2.03, 4.39, having college education or above AOR; 3.1: 2.20, 6.64, family member with glaucoma AOR; 5.86:3.25, 8.0, income 6500 ETB AOR; 2.9: 1.97, 5.00 and previous eye examination AOR; 2.15: 1.46, 4.05 were factors significantly associated with awareness of glaucoma. The main sources of information were news media, family members with glaucoma and health workers. Conclusion More than half (60.91%) of adult ophthalmic patients attending HUCSH were unaware of glaucoma and need eye health education concerning glaucoma.
•Eggshell based zinc-cobalt oxides nanocomposite was prepared.•Nanocomposite was investigated for extraction of hexavalent chromium.•Extraction parameters were optimized for maximum chromium ...extraction.•Experimental equilibrium and kinetic data are collated with models.
In the present work, eggshell-based zinc oxide-cobalt oxide (ES-ZC) nanocomposite was synthesized and used for removal of Cr(VI) from an aqueous solution. The synthesized nanocomposite was characterized using SEM, FTIR, and XRD. The specific surface area of the nanocomposite was also measured using BET and its point of zero charge was determined using a standard method. The effects of adsorption process parameters (adsorption time, pH of solution, adsorbent dose, and initial Cr(VI) concentration) on the response (percent Cr(VI) removal) were investigated using a batch adsorption system. The Cr(VI) adsorption percentage increases with adsorbent dosage. The Cr(VI) adsorption percentage rapidly increases as adsorption time increases from 30 to 90 minutes, however, further increases in adsorption time does not significantly affect the Cr(VI) removal performance. The optimum pH for Cr(VI) adsorption was observed at 2.0, however, a further increase in pH results in a reduction of Cr(VI) removal. Similarly, the initial Cr(VI) concentration negatively affects its removal percentages. The effects of the adsorption process parameters were investigated and optimum Cr(VI) adsorptions were obtained using Response Surface Methodology (RSM) applying Central Composted Design (CCD). The optimum Cr(VI) percent removal obtained by RSM was 94.8% at adsorption time of 90 minutes, pH of 2, adsorbent dose of 1.5 g/L, and initial concentration Cr(VI) of 45 mg/L. The experimental Cr(VI) percent removal at this condition was 93.5 % showing its agreement with the predicted value. . This shows the model can sufficiently estimate the percent of Cr(VI) removal. Moreover, the adsorption kinetics was correlated with pseudo-second-order with R2 value of 0.989. Further, Langmuir isotherm model better fits the current adsorption process with R2 value of 0.999.
Malaria is a major public health concern in Ethiopia. With the increase in malaria cases in the Somali Region of Ethiopia, understanding the distribution and identifying the species of malaria ...vectors is vital to public health. Here we report the first detection of Anopheles stephensi in Ethiopia, a malaria vector typically found in the Middle East, the Indian subcontinent, and China, but recently found in Djibouti.
An entomological investigation was conducted during November to December 2016 in Kebri Dehar town of the Ethiopian Somali Regional State as ancillary work for Anopheles spp. surveillance. Mosquito larvae were collected from water reservoirs. Larvae were reared in the laboratory to the adult stage and identified morphologically. PCR and sequencing of cytochrome oxidase 1 (COI) and internal transcribed spacer 2 (ITS2) loci were performed. Basic Local Alignment Search Tool (BLAST) was used to compare sample sequences to sequences in the NCBI nucleotide database for species identification. To further analyze the relationship between the specimen we collected in Kebri Dehar and other Anopheles samples available in Genbank, phylogenetic analysis was performed using a maximum likelihood approach.
Molecular and morphological results confirm specimens were An. stephensi. The closest high scoring hit was for all specimens was for the An. stephensi sequence. Independent phylogenetic analyses of COI and ITS2 sequences revealed in both cases strong bootstrap (100) support for our sequence forming a clade with other An. stephensi sequences to the exclusion of any other species of Anopheles. In conclusion, Anopheles stephensi is present in Kebri Dehar town in Ethiopia. These findings highlight the need for additional research to examine the role of An. stephensi in malaria transmission in Ethiopia.
Heart Failure (HF) results in an immense impact on the patients' Health-related quality of life (HRQOL). Heart failure patients HRQOL is dependent on the patients' level of engagement in self-care ...behaviors. Therefore this study aimed to determine HF patients' health-related quality of life and its relationship with self-care behaviors.
An institutional-based study was conducted on 284 heart failure patients at the University of Gondar referral hospital. The data were collected using a structured questionnaire-based interview. The data were analyzed using SPSS version 20. Both descriptive and analytical statistical tests were utilized. A multinomial logistic regression analysis was done to determine the association between HRQOL and different independent variables. Variables with a p-value< 0.05 were considered as a significant predictor of the outcome variable.
The finding of this study showed that more than sixty-six percent of the study population were females. The overall mean score of HF patients' quality of life was 46.4 ± 22.4 and the physical and emotional subscale mean score was 20.2 ± 9.8 and 10.5 ± 6.8 respectively. The majority of the study participants 147(51.8%) had poor quality of life. The multinomial logistic regression analysis result showed that rural residence (odds ratio 2.41, 95% CI, 1.23 to 4.71) and inadequate level of self-care practice (odds ratio 2.61, 95% CI, 1.43 to 4.78) were independent predictors of poor HRQOL. The correlation analysis also showed that there was a significant negative relationship between HF patients' HRQOL score and Self-care practice score (r = - 0.127, P = 0.032).
Overall, the majority of HF patients had poor HRQOL. Heart failure patients' HRQOL was significantly associated with place of residence and patients' level of self-care practice. Therefore, patients with HF are required to learn the benefit of self-care behaviors to improve their quality of life and to decrease the disease progression. Furthermore, HF patients who come from rural areas need special emphasis in each follow-up evaluation.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
In Ethiopia, the bacteriological quality of ready-to-eat raw meat is of a great public health concern as it can serve as a source of meat-borne pathogens and worsen the transmission of antimicrobial ...resistant bacteria, and hence this cross-sectional study, done on 257 meat samples (ie., 169 beef, 50 mutton and 38 chevon) from randomly selected hotels and restaurants (n = 52). Approximately 25 gm of meat samples were taken bi-weekly and subjected to quantitative and qualitative analyses; antimicrobial susceptibility tests were done as per the Kirby-Bauer disk diffusion method. It was found that 13.2 (n = 34), 17.5 (n = 45) and 21.8% (n = 56) samples exceeded the permissible limit for total viable and coliform and S. aureus counts, respectively. At the same time, 24.9% (n = 64) surpassed the bacteriological limit permissible for consumption. Overall, 36.6% (n = 94) of samples were extrapolated as unsatisfactory for consumption due to high bacterial load and or the presence of pathogens. Five different bacterial spp. such as E. coli 65% (n = 167), S. aureus 59% (n = 152), Salmonella spp. 28.4% (n = 73), Campylobacter spp. 14.4% (n = 37) and Shigella spp. 4.3% (n = 11) were isolated in varied proportions. Alarmingly, 60% (n = 264) of the isolates were multi-drug resistant and 51% of S. aureus were found to be MRSA.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Diabetes is one of the global public health concern and constipation is frequently seen among gastrointestinal symptoms in diabetes. Despite the fact that constipation is common, doctors and/or ...patients disregard it. This study aimed to determine the prevalence and contributing factors of constipation in patients with diabetes.
Multi-center cross-sectional study was carried out and the data was analyzed using STATA 14. Binary and multilevel logistic regressions were also carried out to identify associated to factors. Factors having a p-value of less than 0.05 were deemed statistically significant in the final model.
206 diabetics participated in the survey. The mean age of the participants was 52.7 years (SD ± 11.9). The prevalence of constipation was 16% (95% CI: 10.97–21.07). Age (AOR = 13.56; 95% CI: 1.71, 107.21), females (AOR = 4.58; 95% CI: 1.76, 11.87), the duration of the diabetes (AOR = 3.16; 95% CI: 1.21, 8.24), and psychological distress (AOR = 12.49, 95% CI: 1.53, 101.8) were significant factors.
The magnitude of constipation was considerable, and it was linked to psychological distress, longer-lasting diabetes, being a woman, and ageing. Patients with type-2 diabetes need to receive careful treatment in order to reduce the severity of the condition and its additional complications.
Abstract
Anemia is a risk factor for adverse cardiovascular disease outcomes in hypertensive patients. Chronic anemia increases preload, reduces afterload, and leads to increased cardiac output in ...hypertension patients. In the long term, this may result in maladaptive left ventricular hypertrophy, which in turn is a well-recognized risk factor for cardiovascular disease outcomes and all-cause mortality in hypertension. Low hemoglobin and hematocrit levels might be strongly indicate hypertensive end-organ damage, specifically kidney failure. Therefore, this study determined the prevalence of anemia and associated factors among hypertensive patients in Referral Hospitals, Amhara Regional State, Ethiopia, in 2020. An institution-based cross-sectional study was conducted in Amhara Regional Referral Hospitals from February 20 to April 30, 2020. Random and systemic sampling techniques were used to select 428 study participants. Data were entered and coded in to Epi data version 3.0 and then exported into STATA 14 for analysis. In bivariable logistic regression, variables with a p-value of < 0.25 were included in multivariable logistic regression. Using a 95% confidence interval, variables having a p-value ≤ 0.05 in multivariable logistic regression were declared as statistically significant variables. In this study, a total of 428 study participants were involved with 99.5% response rate. The prevalence of anemia among hypertensive patients was 17.6%, with a 95% CI (14.3–21.5%). Estimated glomerular filtration rate (eGFR) < 90 ml/min (AOR = 2.77, 95% CI 1.56- 4.92), duration of hypertension (HTN) ≥ 5 years (AOR = 2.37, 95% CI 1.36–4.15), uncontrolled blood pressure (AOR = 1.91, 95% CI 1.08–3.35), and higher pulse pressure (AOR = 1.05 (95% CI 1.02–1.08) were significantly associated with anemia. Nearly one out of five hypertensive patients had anemia. Impaired estimated glomerular filtration rate, duration of HTN, blood pressure status, and pulse pressure were the independent predictors of anemia among hypertensive patients. Screening hemoglobin level at a regular interval is recommended for the hypertensive patients to take an appropriate intervention.
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