The article presents a method for obtaining quantitative signs of pulmonary pathology, based on the analysis of medical imaging computed tomography. These signs may be suitable for the differential ...diagnosis of spherical lung formations. In particular, the possibility of diagnosing cancer and pulmonary tuberculosis was investigated by quantitative statistical characteristics of images of spherical lung formations. Two of these characteristics (the densitometric value and its standard deviation) can be called classical, since modern basic software of computer tomographs can easily calculate them. In addition, characteristics were considered, for which it is necessary to carry out additional calculations using fractal analysis. The article presents the results of a study of the relationship of statistical and fractal characteristics of a tomographic image with the type of pathology in the lungs. The results of a statistical analysis of the fractal dimension of the region of interest and its related parameters are presented, and signs are found suitable for the diagnosis of pulmonary pathologies.
A device for noninvasive measurement of the repetition frequency of single-motor-unit action potential is described. The device was built using virtual instruments in LabVIEW software. The ...mathematical foundations of the measurement method and results are presented.
Abstract
Cavitation bubbles can be seeded from a plasma following optical breakdown, by focusing an intense laser in water. The fast dynamics are associated with extreme states of gas and liquid, ...especially in the nascent state. This offers a unique setting to probe water and water vapor far-from equilibrium. However, current optical techniques cannot quantify these early states due to contrast and resolution limitations. X-ray holography with single X-ray free-electron laser pulses has now enabled a quasi-instantaneous high resolution structural probe with contrast proportional to the electron density of the object. In this work, we demonstrate cone-beam holographic flash imaging of laser-induced cavitation bubbles in water with nanofocused X-ray free-electron laser pulses. We quantify the spatial and temporal pressure distribution of the shockwave surrounding the expanding cavitation bubble at time delays shortly after seeding and compare the results to numerical simulations.
MAGIC is a system of two Imaging Atmospheric Cherenkov Telescopes located in the Canary island of La Palma. Since autumn 2009 both telescopes have been working together in stereoscopic mode, ...providing a significant improvement with respect to the previous single-telescope observations. We use observations of the Crab Nebula taken at low zenith angles to assess the performance of the MAGIC stereo system. The trigger threshold of the MAGIC telescopes is 50−60GeV. Advanced stereo analysis techniques allow MAGIC to achieve a sensitivity as good as (0.76±0.03)% of the Crab Nebula flux in 50h of observations above 290GeV. The angular resolution at those energies is better than ∼0.07°. We also perform a detailed study of possible systematic effects which may influence the analysis of the data taken with the MAGIC telescopes.
The current generation of ground-based imaging atmospheric Cherenkov telescopes (IACTs) operate in the very-high-energy (VHE) domain from ~100 GeV to ~100 TeV. They use electronic digital trigger ...systems to discern the Cherenkov light flashes emitted by extensive air showers (EASs), from the overwhelming light of the night sky (LoNS) background. Near the telescope energy threshold, the number of emitted Cherenkov photons by gamma-ray-induced EASs is comparable to the fluctuations of the LoNS and the photon distribution at the Cherenkov-imaging camera plane becomes patchy. This results in a severe loss of effectiveness of the digital triggers based on combinatorial logic of thresholded signals. A stereoscopic analog trigger system has been developed for improving the detection capabilities of the Major Atmospheric Gamma-ray Imaging Cherenkov (MAGIC) telescopes at the lowest energies. It is based on the analog sum of the photosensor electrical signals. In this article, the architectural design, technical performances, and configuration of this stereoscopic analog trigger, dubbed " Sum-Trigger-II ," are described.
One fundamental question about pulsars concerns the mechanism of their pulsed electromagnetic emission. Measuring the high-end region of a pulsar's spectrum would shed light on this question. By ...developing a new electronic trigger, we lowered the threshold of the Major Atmospheric γ-ray Imaging Cherenkov (MAGIC) telescope to 25 giga--electron volts. In this configuration, we detected pulsed γ-rays from the Crab pulsar that were greater than 25 giga--electron volts, revealing a relatively high cutoff energy in the phase-averaged spectrum. This indicates that the emission occurs far out in the magnetosphere, hence excluding the polar-cap scenario as a possible explanation of our measurement. The high cutoff energy also challenges the slot-gap scenario.
The Perseus galaxy cluster was observed by the MAGIC Cherenkov telescope for a total effective time of 24.4 hr during 2008 November and December. The resulting upper limits on the gamma-ray emission ...above 100 GeV are in the range of 4.6-7.5 x 10{sup -12} cm{sup -2} s{sup -1} for spectral indices from -1.5 to -2.5, thereby constraining the emission produced by cosmic rays, dark matter annihilations, and the central radio galaxy NGC 1275. Results are compatible with cosmological cluster simulations for the cosmic-ray-induced gamma-ray emission, constraining the average cosmic ray-to-thermal pressure to <4% for the cluster core region (<8% for the entire cluster). Using simplified assumptions adopted in earlier work (a power-law spectrum with an index of -2.1, constant cosmic ray-to-thermal pressure for the peripheral cluster regions while accounting for the adiabatic contraction during the cooling flow formation), we would limit the ratio of cosmic ray-to-thermal energy to E{sub CR}/E{sub th} < 3%. Improving the sensitivity of this observation by a factor of about 7 will enable us to scrutinize the hadronic model for the Perseus radio mini-halo: a non-detection of gamma-ray emission at this level implies cosmic ray fluxes that are too small to produce enough electrons through hadronic interactions with the ambient gas protons to explain the observed synchrotron emission. The upper limit also translates into a level of gamma-ray emission from possible annihilations of the cluster dark matter (the dominant mass component) that is consistent with boost factors of {approx}10{sup 4} for the typically expected dark matter annihilation-induced emission. Finally, the upper limits obtained for the gamma-ray emission of the central radio galaxy NGC 1275 are consistent with the recent detection by the Fermi-LAT satellite. Due to the extremely large Doppler factors required for the jet, a one-zone synchrotron self-Compton model is implausible in this case. We reproduce the observed spectral energy density by using the structured jet (spine-layer) model which has previously been adopted to explain the high-energy emission of radio galaxies.
The Materials Imaging and Dynamics (MID) instrument at the European X‐ray Free‐Electron Laser (EuXFEL) facility is described. EuXFEL is the first hard X‐ray free‐electron laser operating in the MHz ...repetition range which provides novel science opportunities. The aim of MID is to enable studies of nano‐structured materials, liquids, and soft‐ and hard‐condensed matter using the bright X‐ray beams generated by EuXFEL. Particular emphasis is on studies of structure and dynamics in materials by coherent scattering and imaging using hard X‐rays. Commission of MID started at the end of 2018 and first experiments were performed in 2019.
The Materials Imaging and Dynamics (MID) instrument at the European X‐ray Free‐Electron Laser facility is described. Recent commissioning results are discussed to illustrate the potential experimental applications of MID.