Here we demonstrate, for the first time, violation of Bell's inequality using a triggered quantum dot photon-pair source without post-selection. Furthermore, the fidelity to the expected Bell state ...is increased above 90% using temporal gating to reject photons emitted at times when collection of uncorrelated light is more probable. A direct measurement of a CHSH Bell inequality is made showing a clear violation, highlighting that a quantum dot entangled photon source is suitable for communication exploiting nonlocal quantum correlations.
Child passenger safety remains an important public health problem because motor vehicle crashes are the leading cause of death for children, and the majority of children ride improperly restrained. ...Using a mobile app to communicate with parents about injury prevention offers promise but little information is available on how to create such a tool. The purpose of this article is to illustrate a theory-based approach to developing a tailored, smartphone app for communicating child passenger safety information to parents. The theoretical basis for the tailoring is the elaboration likelihood model, and we utilized the precaution adoption process model (PAPM) to reflect the stage-based nature of behavior change. We created assessment items (written at ≤6th grade reading level) to determine the child’s proper type of car seat, the parent’s PAPM stage and beliefs on selected constructs designed to facilitate stage movement according to the theory. A message library and template were created to provide a uniform structure for the tailored feedback. We demonstrate how messages derived in this way can be delivered through new m-health technology and conclude with recommendations for the utility of the methods used here for other m-health, patient education interventions.
Abstract
SHADOWS 1, 2 is an intended future beam dump experiment in the CERN North Area, aiming to search for feebly interacting particles (FIPs) 3 created in 400 GeV/c proton interactions. Due to ...its proposed off-axis location alongside the K12 beamline 4, the SHADOWS detector can be placed potentially very close to the beam dump, enabling it to search for FIPs in unexplored parts of the parameter space. In order to guarantee good quality of a potential signal, it is crucial to reduce any backgrounds of Standard Model particles as much as possible. The dominant background downstream the beam dump is caused by muons 1. This introduces the need of a dedicated muon sweeping system consisting of magnetised iron blocks (MIBs) to actively mitigate this background component. We present the conceptional design studies in the framework of the Conventional Beams Working Group of the Physics Beyond Colliders Initiative at CERN 5, 6.
Immune characteristics in 65 calves were evaluated in response to a Bacillus-based direct-fed microbial (DFM) provided in electrolyte scour treatment. Blood samples were analyzed for cell surface ...markers and α1-acid glycoprotein (AGP) concentration. AGP increased in scouring calves given electrolyte containing Bacillus at day 7 post-placement compared to scouring calves administered electrolyte alone and non-scouring calves, enhancing the inflammatory response for pathogen clearance. The Bacillus promotes T cell subsets including greater proportions of activated, mature cells (CD8−CD25+, CD8−CD45RO+, CD8−TCR1+) in calves given electrolyte containing Bacillus than scouring calves administered electrolyte alone and non-scouring calves. Also, the Bacillus may be alleviating inflammation at day 3 post-placement as the proportion of monocytes and granulocytes lacking L-selectin (CD172a+CD62L−) was greater in scouring calves given electrolyte compared to the other groups. Electrolyte containing Bacillus administered at the onset of scours influences components of innate and adaptive immune development during and following the scouring event.
We compare QSO emission-line spectra to predictions based on theoretical ionizing continua of accretion disks. The observed line intensities do not show the expected trend of higher ionization with ...theoretical accretion disk temperature as predicted from the black hole mass and accretion rate. Consistent with earlier studies, this suggests that the inner disk does not reach temperatures as high as expected from standard disk theory. Modified radial temperature profiles, taking account of winds or advection in the inner disk, achieve better agreement with observation. The emission lines of radio-detected and radio-undetected sources show different trends as a function of the theoretically predicted disk temperature.
Aerosols have important effects on the Earth's radiative balance and are normally included in simulations of present day climate. For simulations of present day or recent past climates, observational ...information can be used to constrain spatiotemporal variability in aerosol loading. For the deep past, aerosol changes are generally ignored. Here we describe how to use the Community Climate System Model version 4 (CCSM4), standard boundary conditions for a deep time climate simulation, and pre‐industrial emissions information to generate a “paleogeographic” aerosol prescription. This prescription is then applied to a previously published simulation of the Late Permian (251 Ma) to evaluate the how the model climate is affected by the new aerosol prescription relative to the aerosol distribution originally imposed. The new aerosol prescription results in a broadly warmer and wetter climate with a somewhat stronger Pangaean monsoon. Using spatiotemporally varying and speciated aerosol is equivalent to reducing the optical depth of a uniform background aerosol with sulfate‐like properties by ∼30–50%.
Key Points
Aerosol forcing in deep time climate simulations is often ignored
Ignoring aerosol soon may not be possible in deep time climate modeling
Aerosol forcing can be estimated from pre‐industrial data and paleogeography
Among patients with occlusion of a large intracerebral vessel who had a clinical deficit that was disproportionately severe relative to the infarct volume, 90-day outcomes for disability were better ...with late thrombectomy plus standard care than with standard care alone.
Lung cancer is the most common malignancy in the Western world, and the main risk factor is tobacco smoking. Polymorphisms in metabolic genes may modulate the risk associated with environmental ...factors. The glutathione S-transferase theta 1 gene (GSTT1) is a particularly attractive candidate for lung cancer susceptibility because of its involvement in the metabolism of polycyclic aromatic hydrocarbons found in tobacco smoke and of other chemicals, pesticides, and industrial solvents. The frequency of the GSTT1 null genotype is lower among Caucasians (10–20%) than among Asians (50–60%). The authors present a meta- and a pooled analysis of case-control, genotype-based studies that examined the association between GSTT1 and lung cancer (34 studies, 7,629 cases and 10,087 controls for the meta-analysis; 34 studies, 7,044 cases and 10,000 controls for the pooled analysis). No association was observed between GSTT1 deletion and lung cancer for Caucasians (odds ratio (OR) = 0.99, 95% confidence interval (CI): 0.87, 1.12); for Asians, a positive association was found (OR = 1.28, 95% CI: 1.10, 1.49). In the pooled analysis, the odds ratios were not significant for either Asians (OR = 0.97, 95% CI: 0.83, 1.13) or Caucasians (OR = 1.09, 95% CI: 0.99, 1.21). No significant interaction was observed between GSTT1 and smoking on lung cancer, whereas GSTT1 appeared to modulate occupational-related lung cancer.
We present an exquisite 30 minute cadence Kepler (K2) light curve of the Type Ia supernova (SN Ia) 2018oh (ASASSN-18bt), starting weeks before explosion, covering the moment of explosion and the ...subsequent rise, and continuing past peak brightness. These data are supplemented by multi-color Panoramic Survey Telescope (Pan-STARRS1) and Rapid Response System 1 and Cerro Tololo Inter-American Observatory 4 m Dark Energy Camera (CTIO 4-m DECam) observations obtained within hours of explosion. The K2 light curve has an unusual two-component shape, where the flux rises with a steep linear gradient for the first few days, followed by a quadratic rise as seen for typical supernovae (SNe) Ia. This "flux excess" relative to canonical SN Ia behavior is confirmed in our i-band light curve, and furthermore, SN 2018oh is especially blue during the early epochs. The flux excess peaks 2.14 0.04 days after explosion, has a FWHM of 3.12 0.04 days, a blackbody temperature of K, a peak luminosity of , and a total integrated energy of . We compare SN 2018oh to several models that may provide additional heating at early times, including collision with a companion and a shallow concentration of radioactive nickel. While all of these models generally reproduce the early K2 light curve shape, we slightly favor a companion interaction, at a distance of ∼ based on our early color measurements, although the exact distance depends on the uncertain viewing angle. Additional confirmation of a companion interaction in future modeling and observations of SN 2018oh would provide strong support for a single-degenerate progenitor system.
Antenatal care is essential to promote maternal health. Prior research has focused on barriers women face to attending antenatal care, and improving quality of care is seen as a precondition for ...better attendance. Digital health tools are seen as a promising instrument to increase the quality of healthcare. It is less clear to what extent the use of digital health tools in low- and middle-income counties would be perceived as beneficial by end-users. The aim of this research was to explore women's experiences with antenatal care, and whether digital health tools would change their perceptions of quality of care. This qualitative research utilised an interpretative phenomenological approach on data from semi-structured in-depth interviews collected in 2016 with 19 randomly selected pregnant women from six different dispensaries in Magu District. Findings showed that pregnant women are motivated to attend antenatal care and are grateful for the services received. However, they also articulated a need for improvements in antenatal care services such as the availability of diagnostic tests and more interactions with healthcare workers. Participants indicated that a digital health tool could help in storing patient files and improving communication with health workers. Our results indicate that pregnant women are positive about the use of digital health tools during antenatal care but that the implementation of such a tool should be implemented in parallel to structural service delivery improvements, such as testing availability.
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