In the modern world, Tuberculosis (TB) is regarded as a serious health issue with a high rate of mortality. TB can be cured completely by early diagnosis. For achieving this, one tool utilized is CXR ...(Chest X-rays) which is used to screen active TB. An enhanced deep learning (DL) model is implemented for automatic Tuberculosis detection. This work undergoes the phases like preprocessing, segmentation, feature extraction, and optimized classification. Initially, the CXR image is preprocessed and segmented using AFCM (Adaptive Fuzzy C means) clustering. Then, feature extraction and several features are extracted. Finally, these features are given to the DL classifier Deep Belief Network (DBN). To improve the classification accuracy and to optimize the DBN, a metaheuristic optimization Adaptive Monarch butterfly optimization (AMBO) algorithm is used. Here, the Deep Belief Network with Adaptive Monarch butterfly optimization (DBN-AMBO) is used for enhancing the accuracy, reducing the error function, and optimizing weighting parameters. The overall implementation is carried out on the Python platform. The overall performance evaluations of the DBN-AMBO were carried out on MC and SC datasets and compared over the other approaches on the basis of certain metrics.
Background
The field of laparoscopy has undergone several changes to improve the morbidity and cosmesis of laparoscopic surgery. The robotic single-site surgery is the inevitable hybridization of ...robotic technology with laparoendoscopic single-site surgery.
Methods
Perioperative information of 12 robotic single-site hysterectomies (R-SSH) were collected to evaluate the surgical feasibility and the possible influence of the body mass index (BMI) and the uterine weight on operative times.
Results
The mean operative time was 85 ± 33 min (range, 355 to 149 min), the mean docking time was 9 ± 3 min, and the mean console time was 76 ± 33 min. The mean blood loss was 80 ± 18 mL, and the median weight of resected uteri was 220 ± 45 g. No serious postoperative complications occurred. The CUSUM learning curve was observed to consist of two different phases: phase 1 (the initial 6 cases) and phase 2 (the last 6 cases) with significant reduction in operative and console time observed between the two phases. For BMI, no correlation was found with operative times, console times, and docking times, and no correlation was found between uterine weight and operative time.
Conclusions
This series, identifying two different phases of the learning curve and suggesting that the initial learning phase for the procedure can be achieved after six cases, confirms the feasibility and safety of a robotic approach for single-site hysterectomy. However, the limits of this study mainly rely on the limited casuistic and short follow-up, although the preliminary results appear promising. Larger series and prospective studies comparing R-SSH hysterectomy with standard robotic multiport hysterectomy are necessary to define properly the role of this innovative surgical technique.
Abstract
Objective: To evaluate the effects the administration of myo-inositol (MYO) on hormonal parameters in a group of polycystic ovary syndrome (PCOS) patients.
Design: Controlled clinical study.
...Setting: PCOS patients in a clinical research environment.
Patients: 50 overweight PCOS patients were enrolled after informed consent.
Interventions: All patients underwent hormonal evaluations and an oral glucose tolerance test (OGTT) before and after 12 weeks of therapy (Group A (n¼10): MYO 2 g plus folic acid 200 mg every day; Group B (n¼10): folic acid 200 mg every day). Ultrasound examinations and Ferriman-Gallwey score were also performed.
Main outcome measures: Plasma LH, FSH, PRL, E2, 17OHP, A, T, glucose, insulin, C peptide concentrations, BMI, HOMA index and glucose-to-insulin ratio.
Results: After 12 weeks of MYO administration plasma LH, PRL, T, insulin levels and LH/FSH resulted significantly reduced. Insulin sensitivity, expressed as glucose-to-insulin ratio and HOMA index resulted significantly improved after 12 weeks of treatment. Menstrual cyclicity was restored in all amenorrheic and oligomenorrheic subjects. No changes occurred in the patients treated with folic acid.
Conclusions: MYO administration improves reproductive axis functioning in PCOS patients reducing the hyperinsulinemic state that affects LH secretion.
Celotno besedilo
Dostopno za:
DOBA, IJS, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Wind energy is an essential source of renewable energy that has gained popularity in recent years. Accurately forecasting wind energy production is crucial for efficient energy management and ...distribution. This paper proposes a machine learning-based approach using Support Vector Regression (SVR) and Random Forest Regression (RFR) to forecast wind energy production. The proposed methodology involves data collection, preprocessing, feature selection, model training, optimization, and evaluation. The performance of the models is assessed using mean squared error (MSE), root mean squared error (RMSE), and coefficient of determination (R-squared) metrics. The results indicate that the proposed SVR-RFR model outperforms individual models, achieving a higher accuracy in forecasting wind energy production.
Abstract
In this paper the results of a beam test characterization campaign of 3D trench silicon pixel sensors are presented. A time resolution in the order of 10 ps was measured both for ...non-irradiated and irradiated sensors up to a fluence of 2.5 × 10
16
1 MeV n
eq
cm
−2
. This feature and a detection efficiency close to 99% make this sensors one of the best candidates for 4D tracking detectors in High-Energy-Physics experiments.
Recently, studies on inositol supplementation during in vitro fertilization program (IVF) have gained particular importance due to the effect of this molecule on reducing insulin resistance improving ...ovarian function, oocyte quality, and embryo and pregnancy rates and reducing gonadotropin amount during stimulation. Inositol and its isoforms, especially myoinositol (MYO), are often used as prestimulation therapy in infertile patients undergoing IVF cycle. Inositol supplementation started three months before ovarian stimulation, resulting in significant improvements in hormonal responses, reducing the amount of FSH necessary for optimal follicle development and serum levels of 17beta-estradiol measured the day of hCG injection. As shown by growing number of trials, MYO supplementation improves oocyte quality by reducing the number of degenerated and immature oocytes, in this way increasing the quality of embryos produced. Inositol can also improve the quality of sperm parameters in those patients affected by oligoasthenoteratozoospermia.
Electricity market reforms, pivotal in shaping the energy landscapes of both developed and emerging economies, have garnered significant attention in academic and policy circles. This review, drawing ...from existing research, seeks to understand the nuanced implications of these reforms, particularly on small producers who are integral to the energy matrix. By synthesising insights from seminal works on the subject, we aim to elucidate the multifaceted consequences of electricity market reforms. Our exploration reveals that while reforms can potentially streamline operations and optimise price-cost margins, their tangible impact is moulded by diverse factors, from fuel costs and technological shifts to market structures. The intricate relationship between regulatory accounting, tariff dynamics, and the overarching goals of market regulators emerges as a recurrent theme. As the global energy paradigm undergoes transformation, this review underscores the need for a holistic understanding of market reforms, ensuring a balanced and sustainable energy future for all players in the sector.
3D trench silicon pixel sensors, recently developed by the TimeSPOT collaboration, have shown excellent performance in terms of spatial resolution, timing precision and detection efficiency. The ...combination of these three features make them one of the best candidate for inner tracking detectors operating in high luminosity hadron colliders experiments. This article presents systematic characterisations of these devices made with minimum ionising particles on irradiated sensors with neutrons up to 2.5 ⋅ 10 16 1 MeV n eq cm −2 . The results show that 3D trench pixels have extremely high resistance to radiation. The measured time resolution and the detection efficiency of irradiated sensors match those of non-irradiated ones if a slightly higher bias voltage, few tens of Volts, is applied to the pixels. As of today, 3D trench pixels are the only sensors capable of achieving 10 ps time resolution after being irradiated at extremely high fluences, extending by far the capabilities of future tracking systems of HEP experiments operating under extreme conditions.
For the next generation of vertex detectors, the accurate measurement of the charged particle timing at the pixel level is considered to be the ultimate solution in experiments operating at very high ...instantaneous luminosities. This work shows that the 55 μm × 55 µm wide 150 µm thick 3D trench-type pixels, developed by the TimeSPOT Collaboration, achieve a time resolution close to 10 ps with minimum ionizing particles while maintaining a detection efficiency close to 100% when operated at a tilt angle larger than 10° from normal incidence. This record performance is obtained with software-based constant-fraction algorithms applied to signal waveforms. However, time resolutions as good as 25 ps can be achieved using a simple leading-edge discriminating technique, without any amplitude correction. Similar timing performances can also be achieved when the charged particles cross two nearby pixels if both signal amplitudes are measured. 3D trench-type pixels, as of today, are the fastest charged-particles pixel detectors available and represent a very promising solution for the future upgrade of tracking systems of many HEP experiments operating in extreme conditions.
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