Many prescribers and patients remain reluctant to substitution to generics.
We conducted a prospective observational study, using semi-structured interviews adapted to identify factors independently ...associated with the acceptance of alternative to a generic drug by doctors and patients.
Between December 2014 and August 2015, 108 patients and 73 private doctors from Île-de-France and Nord-Pas-de-Calais were enrolled. Only 48 % of patients thought that the effectiveness and safety of generic were identical to the brand-name, 50 % had a favorable opinion and 36 % said they routinely accept substitution, especially when substitution was proposed by the general practitioner (68 % of patients). Age, gender, occupational status and the presence of a chronic condition were not associated to acceptance of substitution (P>0, 1), unlike the opinion (P<0.001), perception of efficacy (P<0.001) and side effects (P=0.0005). Two thirds of physicians substituted more than 50 % of their brand name prescription to generics. This low figure was due to patient request not to substitute (63.9 %).
The acceptance of substitution was independently associated to patient' opinion about generic drugs, further emphasizing the need for information campaigns dedicated to patients.
2018 JOSPT Award Recipients Simoneau, Guy G
The journal of orthopaedic and sports physical therapy
49, Številka:
3
Journal Article
Recenzirano
During the American Physical Therapy Association's Combined Sections Meeting in Washington, DC in January 2019, JOSPT recognized the authors of the most outstanding research and clinical practice ...manuscripts published in JOSPT during 2018. The 2018 George J. Davies-James A. Gould Excellence in Clinical Inquiry Award was presented to Joseph R. Kardouni, PT, PhD; Tracie L. Shing, MPH; Craig J. McKinnon, MPH; Dennis E. Scofield, MAEd; and Susan P. Proctor, DSc for their July 2018 article, "Risk for Lower Extremity Injury After Concussion: A Matched Cohort Study in Soldiers." The 2018 JOSPT Excellence in Research Award was presented to Kathryn J. Schneider, PT, PhD; Willem H. Meeuwisse, MD, PhD; Luz Palacios-Derflingher, PhD; and Carolyn A. Emery, PT, PhD for their December 2018 article, "Changes in Measures of Cervical Spine Function, Vestibulo-ocular Reflex, Dynamic Balance, and Divided Attention Following Sport-Related Concussion in Elite Youth Ice Hockey Players." J Orthop Sports Phys Ther 2019;49(3):117. doi:10.2519/jospt.2019.0101.
As the door closes on 2018, Interim Editor-in-Chief Dr. Guy Simoneau expresses his gratitude and recognizes the many colleagues who contributed to the editorial process of JOSPT over the past 12 ...months. It is through their commitment, talent, and knowledge that JOSPT can continue to publish high-quality content that leads to more effective clinical practice and improved patient outcomes. J Orthop Sports Phys Ther 2018;48(12):908-910. doi:10.2519/jospt.2018.0108.
2017 JOSPT Award Recipients Simoneau, Guy G
The journal of orthopaedic and sports physical therapy
48, Številka:
5
Journal Article
Recenzirano
During the American Physical Therapy Association's Combined Sections Meeting in New Orleans, LA in February 2018, JOSPT recognized the authors of the most outstanding research and clinical practice ...manuscripts published in JOSPT during 2017. The 2017 George J. Davies-James A. Gould Excellence in Clinical Inquiry Award was presented to Noa Ben-Ami, PT, PhD; Gabriel Chodick, MHA, PhD; Yigal Mirovsky, MD; Tamar Pincus, MPhil, MSc, PhD; and Yair Shapiro, MD, PhD, for their February 2017 article "Increasing Recreational Physical Activity in Patients With Chronic Low Back Pain: A Pragmatic Controlled Clinical Trial." The 2017 JOSPT Excellence in Research Award was presented to Sanneke Don, PT, MPT; Margot de Kooning, PT, PhD; Lennard Voogt, PT, MT, PhD; Kelly Ickmans, PT, PhD; Liesbeth Daenen, PT, PhD; and Jo Nijs, PT, MT, PhD, for their March 2017 article "The Effect of Visual Feedback of the Neck During Movement in People With Chronic Whiplash-Associated Disorders: An Experimental Study." J Orthop Sports Phys Ther 2018;48(5):348. doi:10.2519/jospt.2018.0104.
The Challenge of Sharing New Information Simoneau, Guy G
The journal of orthopaedic and sports physical therapy,
01/2018, Letnik:
48, Številka:
1
Journal Article
Recenzirano
Interim Editor-in-Chief Guy Simoneau opens 2018 with an introduction to the returning and new members of the editorial board, and a preview of the January issue of JOSPT. J Orthop Sports Phys Ther ...2018;48(1):1-2. doi:10.2519/jospt.2018.0101.
Positioning a computer keyboard with a downward slope reduces wrist extension needed to use the keyboard and has been shown to decrease pressure in the carpal tunnel. However, whether a downward ...slope of the keyboard reduces electromyographic (EMG) activity of the forearm muscles, in particular the wrist extensors, is not known.
Sixteen experienced typists participated in this study and typed on a conventional keyboard that was placed on slopes at angles of 7.5, 0, -7.5, and -15 degrees. Electromyographic activity of the extensor carpi ulnaris (ECU), flexor carpi ulnaris (FCU), and flexor carpi radialis (FCR) muscles was measured with surface electrodes, while the extension and ulnar deviation angles of the right and left wrists were measured with electrogoniometers.
Wrist extension angle decreased from approximately 12 degrees of extension while typing on a keyboard with a 7.5-degree slope to 3 degrees of flexion with the keyboard at a slope of -15 degrees. Although the differences were in the range of 1% to 3% of maximum voluntary contraction (MVC), amplitude probability distribution function (APDF) of root-mean-square EMG data points from the ECU, FCU, and FCR muscles varied across keyboard slopes.
Wrist extension decreased as the keyboard slope decreased. Furthermore, a slight decrease in percentage of MVC of the ECU muscle was noted as the keyboard slope decreased. Based on biomechanical modeling and published work on carpal tunnel pressure, both of these findings appear to be positive with respect to comfort and fatigue, but the exact consequences of these findings on the reduction or prevention of injuries have yet to be determined. The results may aid physical therapists and ergonomists in their evaluations of computer keyboard workstations and in making recommendations for interventions with regard to keyboard slope angle.
Celotno besedilo
Dostopno za:
DOBA, FSPLJ, IZUM, KILJ, NUK, OILJ, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK, VSZLJ
Postural instability in patients with diabetic sensory neuropathy.
G G Simoneau ,
J S Ulbrecht ,
J A Derr ,
M B Becker and
P R Cavanagh
Program in Physical Therapy, Marquette University, Milwaukee, ...Wisconsin.
Abstract
OBJECTIVE--Recent survey evidence suggests that sensory ataxia due to diabetic neuropathy may be a more frequent and serious
problem than is commonly recognized. This view is further supported by research that confirms the major contribution of the
somatosensory system to the control of posture. We therefore sought to determine the effects of significant diabetic distal
symmetrical polyneuropathy on the control of posture. RESEARCH DESIGN AND METHODS--Fifty-one subjects, divided into three
groups, participated in this study. Seventeen had diabetes and significant sensory neuropathy, 17 had diabetes and no neuropathy,
and 17 had neither diabetes nor neuropathy. The subjects were matched across groups, and stringent exclusion criteria were
applied. Postural stability during quiet standing was measured using a force platform. In addition to electrophysiological
and quantitative sensory tests of neuropathy, a number of physical and functional characteristics were measured for all subjects.
RESULTS--Postural instability was found to be significantly associated with sensory neuropathy, but not with diabetes per
se. Patients with sensory neuropathy demonstrated between 66 and 117% more instability than did control subjects (depending
on the testing condition). Based on multiple linear regression analyses, the most significant correlates of instability were
the quantitative sensory measures of neuropathy and age. CONCLUSIONS--The loss of sensory perception secondary to diabetic
distal symmetrical sensory neuropathy has a markedly detrimental effect on postural stability. The deficit is greatest when
visual or vestibular cues are absent or degraded. Patients with neuropathy need to be informed of the postural consequences
of this condition to limit the potential morbidity caused by falls.
In this editorial of his final issue as Editor-in-Chief, Dr Guy G. Simoneau shares his thoughts on how changes in the areas of physical therapy research design, professional collaboration, publishing ...and communication technology, and publication standards played out in the world of JOSPT and recognize the many people who supported and implemented the changes.
During the American Physical Therapy Association's Combined Sections Meeting in Anaheim, California in February 2016, JOSPT recognized the authors of the most outstanding research and clinical ...practice manuscripts published in JOSPT during the 2015 calendar year. The 2015 JOSPT Excellence in Research Award was presented to Björn Aasa, Lars Berglund, Peter Michaelson, and Ulrika Aasa for their paper titled "Individualized Low-Load Motor Control Exercises and Education Versus a High-Load Lifting Exercise and Education to Improve Activity, Pain Intensity, and Physical Performance in Patients With Low Back Pain: A Randomized Controlled Trial." The 2015 George J. Davies-James A. Gould Excellence in Clinical Inquiry Award was presented to Anne Benjaminse, Alli Gokeler, Bert Otten, Ariel V. Dowling, Avery Faigenbaum, Kevin R. Ford, Timothy E. Hewett, James A. Onate, and Gregory D. Myer for their work titled "Optimization of the Anterior Cruciate Ligament Injury Prevention Paradigm: Novel Feedback Techniques to Enhance Motor Learning and Reduce Injury Risk."
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