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zadetkov: 26
1.
  • Effect of HBB genotype on s... Effect of HBB genotype on survival in a cohort of transfusion-dependent thalassemia patients in Cyprus
    Kountouris, Petros; Michailidou, Kyriaki; Christou, Soteroula ... Haematologica (Roma), 09/2021, Letnik: 106, Številka: 9
    Journal Article
    Recenzirano
    Odprti dostop

    Initiation of regular transfusion in transfusion-dependent thalassemia (TDT) is based on the assessment of clinical phenotype. Pathogenic HBB variants causing β-thalassemia are important determinants ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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2.
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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3.
  • Distinct miRNA Signatures a... Distinct miRNA Signatures and Networks Discern Fetal from Adult Erythroid Differentiation and Primary from Immortalized Erythroid Cells
    Papasavva, Panayiota L; Papaioannou, Nikoletta Y; Patsali, Petros ... International journal of molecular sciences, 03/2021, Letnik: 22, Številka: 7
    Journal Article
    Recenzirano
    Odprti dostop

    MicroRNAs (miRNAs) are small non-coding RNAs crucial for post-transcriptional and translational regulation of cellular and developmental pathways. The study of miRNAs in erythropoiesis elucidates ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK

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4.
  • Relative and Absolute Quant... Relative and Absolute Quantification of Aberrant and Normal Splice Variants in HBBIVSI−110 (G > A) β-Thalassemia
    Patsali, Petros; Papasavva, Panayiota; Christou, Soteroulla ... International journal of molecular sciences, 09/2020, Letnik: 21, Številka: 18
    Journal Article
    Recenzirano
    Odprti dostop

    The β-thalassemias are an increasing challenge to health systems worldwide, caused by absent or reduced β-globin (HBB) production. Of particular frequency in many Western countries is HBBIVSI−110(G > ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK

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5.
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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6.
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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7.
  • Evaluation of Mono- and Bi-... Evaluation of Mono- and Bi-Functional GLOBE-Based Vectors for Therapy of β-Thalassemia by HBBAS3 Gene Addition and Mutation-Specific RNA Interference
    Koniali, Lola; Flouri, Christina; Kostopoulou, Markela I. ... Cells (Basel, Switzerland), 12/2023, Letnik: 12, Številka: 24
    Journal Article
    Recenzirano
    Odprti dostop

    Therapy via the gene addition of the anti-sickling βAS3-globin transgene is potentially curative for all β-hemoglobinopathies and therefore of particular clinical and commercial interest. This study ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
8.
  • High-efficiency editing in ... High-efficiency editing in hematopoietic stem cells and the HUDEP-2 cell line based on in vitro mRNA synthesis
    Papaioannou, Nikoletta Y; Patsali, Petros; Naiisseh, Basma ... Frontiers in genome editing, 03/2023, Letnik: 5
    Journal Article
    Recenzirano
    Odprti dostop

    Genome editing tools, such as CRISPR/Cas, TALE nucleases and, more recently, double-strand-break-independent editors, have been successfully used for gene therapy and reverse genetics. Among various ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK
9.
  • Proteomic Studies for the I... Proteomic Studies for the Investigation of γ-Globin Induction by Decitabine in Human Primary Erythroid Progenitor Cultures
    Theodorou, Andria; Phylactides, Marios; Katsantoni, Eleni ... Journal of clinical medicine, 01/2020, Letnik: 9, Številka: 1
    Journal Article
    Recenzirano
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    Reactivation of γ-globin is considered a promising approach for the treatment of β-thalassemia and sickle cell disease. Therapeutic induction of γ-globin expression, however, is fraught with lack of ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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10.
  • A novel mutation in the ery... A novel mutation in the erythroid transcription factor KLF1 is likely responsible for ameliorating β‐thalassemia major
    Fanis, Pavlos; Kousiappa, Ioanna; Phylactides, Marios ... Human mutation, October 2019, Letnik: 40, Številka: 10
    Journal Article
    Recenzirano
    Odprti dostop

    We describe the identification of a novel missense mutation in the second zinc finger of KLF1 in two siblings who, based on their genotype, are predicted to suffer from beta thalassemia major but ...
Celotno besedilo
Dostopno za: BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK

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zadetkov: 26

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