There is narrow space and harsh environment underground coal mines. When radio signals are transmitted, diffraction, attenuation, multi-path and scattering are often very serious. All the problems ...make the WSN system difficult to reach the set bit error rate when transmitting images. V-MIMO, which makes every node of the WSN work together, is adopted in the paper. In order to improve the system capability and reliability, virtual multi-antennas receive- diversity-aided method is also used in the paper. What's more, considering the peculiarity of transmission underground coal mines, the paper uses OFDM wireless transmission to take further advantage of MIMO and improve the reliability in data transmission. So it is possible for the WSN system to transmit image signals underground coal mines.
In order to make sure that the Wireless Sensor Networks can transmit signals efficiently and reliably in uneven, heterogeneous and limited space, the V-MIMO-OFDM mode is used underground coal mines. ...It allows the nodes equipped with single antenna to process information and transmit collaboratively, so multi-path fading can be resisted efficiently. The energy consumption of SISO, V-MIMO and V-MIMO-OFDM system is studied in this paper. It can be seen from the energy consumption curve that the V-MIMO system can reduce the energy consumption. In a short communication distance, the energy consumption of the V-MIMO system is more than the SISO. But over a certain distance, it is quite the opposite. The V-MIMO-OFDM system further shortens the communication distance. Therefore, the adoption of V-MIMO-OFDM system underground coal mines can greatly reduce the bit error rate and energy consumption. energy consumption.
Although adenomyosis is a largely benign disease,malignant transformations do happen in rare cases,resulting in endometrioid adenocarcinoma or sarcoma in the myometrium.Recently, attention has been ...focused on the malignant transformation of the endometriosis.In 1988, the concept of atypical endometriosis （aEM） was first proposed by LaGrenade and Silverberg,1 who suggested that aEM might be a precursor of malignant transformations of endometriosis.However, the majority of investigations of aEM focus on endometriosis, while adenomyosis remains understudied.In this article, we report 10 cases of atypical glandular hyperplasia transformation of adenomyosis, of whom the clinical and pathological characteristics are observed.
Background： There has been no external validation of survival prediction models for severe adult respiratory distress syndrome （ARDS） with extracorporeal membrane oxygenation （ECMO） therapy in China. ...The aim of study was to compare the performance of multiple models recently developed for patients with ARDS undergoing ECMO based on Chinese single-center data. Methods： A retrospective case study was performed, including twenty-three severe ARDS patients who received ECMO from January 2009 to July 2015. The PRESERVE （Predicting death for severe ARDS on VV-ECMO）, ECMOnet, Respiratory Extracorporeal Membrane Oxygenation Survival Prediction （RESP） score, a center-specific model developed lbr inter-hospital transfers receiving ECMO, and the classical risk-prediction scores of Acute Physiology and Chronic Health Evaluation （APACHE） II and Sequential Organ Failure Assessment （SOFA） were calculated. In-hospital and six-month mortality were regarded as the endpoints and model performance was evaluated by comparing the area under the receiver operating characteristic curve （AUC）. Results： The RESP and APACHE II scores showed excellent discriminate performance in predicting survival with AUC of 0.835 （95% confidence interval CI, 0.659-1 .010, P = 0.007） and 0.762 （95% CI, 0.558-0.965, P = 0.035）, respectively. The optimal cutoff values were risk class 3.5 for RESP and 35.5 for APACHE II score, and both showed 70.0% sensitivity and 84.6% specificity. The excellent performance of these models was also evident for the pneumonia etiological subgroup, for which the SOFA score was also shown to be predictive, with an AUC of 0.790 （95% CI, 0.571-1.009, P = 0.038）. However, the ECMOnet and the score developed for externally retrieved ECMO patients failed to demonstrate significant discriminate power for the overall cohort. The PRESERVE model was unable to be evaluated fully since Conclusions： The RESP, APCHAE 11, and SOFA scorings only one patient died six months postdischarge. systems show good predictive value for intra-hospital survival of ARDS patients treated with ECMO in our single-center evaluation. Future validation should include a larger study with either more patients＇ data at single-center or by integration of domestic multi-center data. Development of a scoring system with national characteristics might be warranted.
In micro-blogging, people talk about their daily life and change minds freely, thus by mining people's interest in micro-blogging, we will easily perceive the pulse of society. In this paper, we ...catch what people are caring about in their daily life by discovering meaningful communities based on probabilistic factor model (PFM). The proposed solution identifies people's interest from their friendship and content information. Therefore, it reveals the behaviors of people in micro-blogging naturally. Experimental results verify the effectiveness of the proposed model and show people's social life vividly.
Background Incretin-based therapies provide additional options for treating type 2 diabetes. We aimed to evaluate the efficacy and tolerability of exenatide monotherapy in obese patients with type 2 ...diabetes. Methods A 26-week, metformin controlled, parallel-group study was conducted among antidiabetic drug-naive obese patients aged 〉18 years, and with type 2 diabetes. Participating patients were randomly assigned to receive exenatide or metformin treatments. Results Fifty-nine patients （age （50.5±8.6） years, body mass index （BMI） （30.2±1.6） kg/m2, and hemoglobin AIC （HbAc （8.2±1.2）%） were enrolled in the study. Glucose control and weight reduction improved in both groups receiving treatment. HbAlc and oral glucose tolerance test （OGTT） 2 hour glycemia reduction with exenatide was superior to that obtained with metformin （（-2.10±1.79）% vs. （-1.66±1.38）%, （-5.11±2.68） mmol/L vs. （-2.80±2.70） mmol/L, P 〈0.05）. Fast plasma glucose （FPG） reduction was not significantly different between the two groups （（-1.8±2.0） mmol/L vs. （-1.6±1.7） mmol/L, P 〉0.05）. Patients treated with exenatide achieved HbAlc of 〈7% （97% of patients） and 〈6.5% （79%） at end-point, vs. 93% and 73% with metformin （P 〉0.05）. Greater weight reduction was also achieved with exenatide （（-5.80±3.66） kg） than with metformin （（-3.81±1.38） kg, P 〈0.01）. Homeostasis model assessment of beta-cell function （HOMA-B） was not significantly increased, but the insulinogenic index and HOMA for insulin sensitivity （HOMA-S） were greatly improved in the exenatide group （P 〈0.05）. Nausea was the most common adverse effect in exenatide treatment （30% vs. 8%; P 〈0.05）, but most cases were of mild to moderate intensity. One case in the exenatide group was withdrawn early because of severe nausea. Hypoglycemia events were often observed during the first 4 weeks, with 12% of patients in the exenatide and 3.2% in metformin groups, respectively （P 〈0.05）. No incidents of severe hypoglycemia were reported. Conclusions Exenatide demonstrated more beneficial effects on HbAlc, weight reduction and insulin resistance during 26 weeks of treatment, but there were more hypoglycemic events and mild-to-moderate nausea compared with metformin. These results suggested that exenatide monotherapy may provide a viable treatment option in newly developed type 2 diabetes.
AIM： To study the effect of discoidin I-like domaincontaining protein 3（EDIL3） depletion on the proliferation and epithelial-mesenchymal transition（EMT） in human lens epithelial cells（LECs）. METHODS： ...RNA interference was used to inhibit the expression of EDIL3 in human LECs in vitro. The morphology of cells was observed using an inverted microscope. Cell proliferation was assessed using Ed U kit. Cell migration was investigated using Transwell chamber and EMT of LECs was assessed using confocal microscope and Western blotting. The transforming growth factor β（TGFβ） pathway was investigated using Western blotting. RESULTS： The data showed that silencing EDIL3 expression changed LECs morphology and suppressed LECs proliferation（P〈0.05） and migration（P〈0.01）. Furthermore, the result of Western blotting showed that EDIL3 depletion reduced the expression of α-smooth muscle actin（α-SMA）（P〈0.001） and vimentin（P〈0.01）, while increased the expression of E-cadherin（P〈0.001）. EDIL3 depletion could suppress the phosphorylation of Smad2（P〈0.01） and Smad3（P〈0.01） and the activation of exracellular signal regulated kinase（ERK）（P〈0.05）. CONCLUSION： The findings indicate that EDIL3 might participate in the proliferation and EMT in LECs via TGFβ pathway and may be a potential therapeutic target for the treatment of posterior capsule opacification.
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