In recent years, spirocyclic compounds have attracted a significant interest in medicinal chemistry due to their considerable biological activities. The general and widely used concept for ...spirocyclic compound synthesis is related with dearomatization of starting material. However, most of the libraries prepared using this concept comprise structure similarity. Therefore, preparation of structurally distinct libraries comprising varied functionality requires different approaches and that includes non‐dearomative pathways. In given review recent advance in the synthesis of structurally varied spirocycles via radical‐mediated non‐dearomative strategies is discussed. In this context, application of radical initiators or photoredox catalysis is described. The variety of the presented examples indicates the high potential of the visible‐light‐induced methodologies in spirocyclic compound synthesis, which can act as a very efficient green alternative to known procedures, offering mild reaction conditions and high functional group tolerance.
The single-mirror small-size telescope (SST-1M) is one of the three proposed designs for the small-size telescopes (SSTs) of the Cherenkov Telescope Array (CTA) project. The SST-1M will be equipped ...with a 4 m-diameter segmented reflector dish and an innovative fully digital camera based on silicon photo-multipliers. Since the SST sub-array will consist of up to 70 telescopes, the challenge is not only to build telescopes with excellent performance, but also to design them so that their components can be commissioned, assembled and tested by industry. In this paper we review the basic steps that led to the design concepts for the SST-1M camera and the ongoing realization of the first prototype, with focus on the innovative solutions adopted for the photodetector plane and the readout and trigger parts of the camera. In addition, we report on results of laboratory measurements on real scale elements that validate the camera design and show that it is capable of matching the CTA requirements of operating up to high moonlight background conditions.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
We present measurements of the pseudorapidity distribution of primary charged particles produced in Au+Au collisions at three energies, sqrts(NN)=19.6, 130, and 200 GeV, for a range of collision ...centrali-ties. The distribution narrows for more central collisions and excess particles are produced at high pseudorapidity in peripheral collisions. For a given centrality, however, the distributions are found to scale with energy according to the "limiting fragmentation" hypothesis. The universal fragmentation region described by this scaling grows in pseudorapidity with increasing collision energy, extending well away from the beam rapidity and covering more than half of the pseudorapidity range over which particles are produced. This approach to a universal limiting curve appears to be a dominant feature of the pseudorapidity distribution and therefore of the total particle production in these collisions.
This paper describes the evaporative system used to cool the silicon detector structures of the inner detector sub-detectors of the ATLAS experiment at the CERN Large Hadron Collider. The motivation ...for an evaporative system, its design and construction are discussed. In detail the particular requirements of the ATLAS inner detector, technical choices and the qualification and manufacture of final components are addressed. Finally results of initial operational tests are reported. Although the entire system described, the paper focuses on the on-detector aspects. Details of the evaporative cooling plant will be discussed elsewhere.
The PHOBOS detector at RHIC Back, B.B; Baker, M.D; Barton, D.S ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
03/2003, Letnik:
499, Številka:
2
Journal Article
Recenzirano
This manuscript contains a detailed description of the PHOBOS experiment as it is configured for the Year 2001 running period. It is capable of detecting charged particles over the full solid angle ...using a multiplicity detector and measuring identified charged particles near mid-rapidity in two spectrometer arms with opposite magnetic fields. Both of these components utilize silicon pad detectors for charged particle detection. The minimization of material between the collision vertex and the first layers of silicon detectors allows for the detection of charged particles with very low transverse momenta, which is a unique feature of the PHOBOS experiment. Additional detectors include a time-of-flight wall which extends the particle identification range for one spectrometer arm, as well as sets of scintillator paddle and Cherenkov detector arrays for event triggering and centrality selection.
The T2K Side Muon Range Detector (SMRD) Aoki, S.; Barr, G.; Batkiewicz, M. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
01/2013, Letnik:
698
Journal Article
Recenzirano
Odprti dostop
The T2K experiment is a long baseline neutrino oscillation experiment aiming to observe the appearance of νe in a νμ beam. The νμ beam is produced at the Japan Proton Accelerator Research Complex ...(J-PARC), observed with the 295km distant Super-Kamiokande Detector and monitored by a suite of near detectors at 280m from the proton target. The near detectors include a magnetized off-axis detector (ND280) which measures the unoscillated neutrino flux and neutrino cross-sections. The present paper describes the outermost component of ND280 which is a Side Muon Range Detector (SMRD) composed of scintillation counters with embedded wavelength shifting fibers and Multi-Pixel Photon Counter readout. The components, performance and response of the SMRD are presented.
The single mirror Small Size Telescope (SST-1M) is one of the proposed designs for the smallest type of telescopes, SSTs that will compose the Cherenkov Telescope Array (CTA).
The SST-1M camera will ...use Silicon PhotoMultipliers (SiPM) which are nowadays commonly used in High Energy Physics experiments and many imaging applications. However the unique pixel shape and size have required a dedicated development by the University of Geneva and Hamamatsu. The resulting sensor has a surface of ∼94mm2 and a total capacitance of ∼3.4nF. These unique characteristics, combined with the stringent requirements of the CTA project on timing and charge resolution have led the University of Geneva to develop custom front-end electronics.
The preamplifier stage has been tailored in order to optimize the signal shape using measurement campaigns and electronic simulation of the sensor. A dedicated trans-impedance pre-amplifier topology is used resulting in a power consumption of 400mW per pixel and a pulse width <30ns. The measurements that have led to the choice of the different components and the resulting performance are detailed in this paper.
The slow control electronics was designed to provide the bias voltage with 6.7mV precision and to correct for temperature variation with a forward feedback compensation with 0.17°C resolution. It is fully configurable and can be monitored using CANbus interface. The architecture and the characterization of the various elements are presented.
Polymer and carbon composite materials reinforced with K-1100 ultra-high modulus fibers were subject to testing of their radiation resistance. Mechanical tests have been carried out, prior and after ...neutron irradiation at a dose of 7.1×10
17 n/cm
2 (
E>0.5 MeV) for organic matrix composite and 7.3×10
17 n/cm
2 (
E>0.5 MeV) for carbon matrix composite, to assess the radiation resistance. Flexural strength, deformation at break, Young’s modulus and dimensional changes were measured. Microstructure of the composites before and after irradiation was analyzed. The results showed that neutron irradiation causes significant changes in mechanical properties of composites with organic and carbon matrix and a slight variation in their dimensions. Stronger effects in mechanical properties changes for composites with carbon matrix were observed.
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