Kramers-Kronig analysis is commonly used to estimate the optical properties of new materials. The analysis typically uses data from far infrared through near ultraviolet (say 40-40 000 cm super(-1) ...or 5 meV-5 eV) and uses extrapolations outside the measured range. Most high-frequency extrapolations use a power law, 1/ omega super(n), transitioning to 1/ omega super(4) at a considerably higher frequency and continuing this free-carrier extension to infinity. The midrange power law is adjusted to match the slope of the data and to give pleasing curves, but the choice of power (usually between 0.5 and 3) is arbitrary. Instead of an arbitrary power law, it is better to use x-ray atomic scattering functions such as those presented by Henke and co-workers. These basically treat the solid as a linear combination of its atomic constituents and, knowing the chemical formula and the density, allow the computation of dielectric function, reflectivity, and other optical functions. The "Henke reflectivity" can be used over photon energies of 10 eV to 34 keV, after which a 1/ omega super(4) continuation is perfectly fine. The bridge between experimental data and the Henke reflectivity as well as two corrections made to the latter are discussed.
Axions are a promising cold dark matter candidate. Haloscopes, which use the conversion of axions to photons in the presence of a magnetic field to detect axions, are the basis of microwave cavity ...searches such as the Axion Dark Matter eXperiment (ADMX). To search for lighter, low frequency axions in the sub- 2 × 10 − 7 eV (50 MHz) range, a tunable lumped-element LC circuit has been proposed. For the first time, through ADMX SLIC (Superconducting LC Circuit Investigating Cold Axions), a resonant LC circuit was used to probe this region of axion mass-coupling space. The detector used a superconducting LC circuit with piezoelectric driven capacitive tuning. The axion mass and corresponding frequency ranges 1.7498 – 1.7519 × 10 − 7 eV (42.31–42.36 MHz), 1.7734 – 1.7738 × 10 − 7 eV (42.88–42.89 MHz), and 1.8007 – 1.8015 × 10 − 7 eV (43.54–43.56 MHz) were covered at magnetic fields of 4.5 T, 5.0 T, and 7.0 T, respectively. Exclusion results from the search data, for coupling below 10 − 12 GeV − 1 , are presented.
We show that dark matter axions cause an oscillating electric current to flow along magnetic field lines. The oscillating current induced in a strong magnetic field B0 produces a small magnetic field ...Ba. We propose to amplify and detect Ba using a cooled LC circuit and a very sensitive magnetometer. This appears to be a suitable approach to searching for axion dark matter in the 10(-7) to 10(-9) eV mass range.
This Letter reports the results from a haloscope search for dark matter axions with masses between 2.66 and 2.81 μeV. The search excludes the range of axion-photon couplings predicted by plausible ...models of the invisible axion. This unprecedented sensitivity is achieved by operating a large-volume haloscope at subkelvin temperatures, thereby reducing thermal noise as well as the excess noise from the ultralow-noise superconducting quantum interference device amplifier used for the signal power readout. Ongoing searches will provide nearly definitive tests of the invisible axion model over a wide range of axion masses.
Silk is a source of marvel for centuries as one of nature's high‐performance materials. More recently, chemical and structural analysis techniques have helped explore the relationship between silk's ...properties and its hierarchical structure. Furthermore, recombinant protein engineering as well as polymer and organic synthesis techniques have enabled the production of silk‐like materials. It has become apparent that silk is a supramolecular polymer with many of the properties exhibited by well‐known synthetic supramolecular materials, such as block copolymers, liquid crystals, thermoplastic elastomers, and self‐assembling peptides. In this review, the hierarchical structure and supramolecular assembly of silk are discussed in comparison to these synthetic supramolecular systems. By focusing on the connections between chemical structure, nanoscale molecular organization, and material properties, the aim is to provide perspectives on the rational design of advanced soft matter to supramolecular chemists and molecular engineers who look to nature for inspiration.
Silk and silk‐mimetic materials exhibit many supramolecular properties. In this review, the hierarchical structure and self‐assembly of silk are discussed from a supramolecular chemistry perspective. Furthermore, meaningful comparisons to well‐studied synthetic supramolecular systems with chemical and structural parallels to silk are explored.
Near-field radiation allows heat to propagate across a small vacuum gap at rates several orders of magnitude above that of far-field, blackbody radiation. Although heat transfer via near-field ...effects has been discussed for many years, experimental verification of this theory has been very limited. We have measured the heat transfer between two macroscopic sapphire plates, finding an increase in agreement with expectations from theory. These experiments, conducted near 300 K, have measured the heat transfer as a function of separation over mm to μm and as a function of temperature differences between 2.5 and 30 K. The experiments demonstrate that evanescence can be put to work to transfer heat from an object without actually touching it.
The μeV axion is a well-motivated extension to the standard model. The Axion Dark Matter eXperiment (ADMX) collaboration seeks to discover this particle by looking for the resonant conversion of ...dark-matter axions to microwave photons in a strong magnetic field. In this Letter, we report results from a pathfinder experiment, the ADMX "Sidecar," which is designed to pave the way for future, higher mass, searches. This testbed experiment lives inside of and operates in tandem with the main ADMX experiment. The Sidecar experiment excludes masses in three widely spaced frequency ranges (4202-4249, 5086-5799, and 7173-7203 MHz). In addition, Sidecar demonstrates the successful use of a piezoelectric actuator for cavity tuning. Finally, this publication is the first to report data measured using both the TM_{010} and TM_{020} modes.
The human genome contains "dark" gene regions that cannot be adequately assembled or aligned using standard short-read sequencing technologies, preventing researchers from identifying mutations ...within these gene regions that may be relevant to human disease. Here, we identify regions with few mappable reads that we call dark by depth, and others that have ambiguous alignment, called camouflaged. We assess how well long-read or linked-read technologies resolve these regions.
Based on standard whole-genome Illumina sequencing data, we identify 36,794 dark regions in 6054 gene bodies from pathways important to human health, development, and reproduction. Of these gene bodies, 8.7% are completely dark and 35.2% are ≥ 5% dark. We identify dark regions that are present in protein-coding exons across 748 genes. Linked-read or long-read sequencing technologies from 10x Genomics, PacBio, and Oxford Nanopore Technologies reduce dark protein-coding regions to approximately 50.5%, 35.6%, and 9.6%, respectively. We present an algorithm to resolve most camouflaged regions and apply it to the Alzheimer's Disease Sequencing Project. We rescue a rare ten-nucleotide frameshift deletion in CR1, a top Alzheimer's disease gene, found in disease cases but not in controls.
While we could not formally assess the association of the CR1 frameshift mutation with Alzheimer's disease due to insufficient sample-size, we believe it merits investigating in a larger cohort. There remain thousands of potentially important genomic regions overlooked by short-read sequencing that are largely resolved by long-read technologies.
We explore the application of heterodyne interferometry for a weak-field coherent detection scheme. The methods detailed here will be used in ALPS II, an experiment designed to search for weakly ...interacting, sub-eV particles. For ALPS II to reach its design sensitivity this detection system must be capable of accurately measuring fields with equivalent amplitudes on the order of 10−5 photons / s or greater. We present initial results of an equivalent dark count rate on the order of 10−5 photons / s as well as successful generation and detection of a signal with a field strength equivalent to 10−2 photons / s .