هدفت الدراسة إلى تقييم فعالية مغلي أوراق الشجرة المعروفة بالمورينجا في إزالة الطبقة السميكة مقارنة بمادتين أخريين وكذلك الأنشطة المضادة للميكروبات.
تم استخراج أوراق الشجرة باستخدام مغلي الماء الساخن ...بتركيزين مختلفين. تم تحضير ما مجموعه ثلاثين سنا بشريا مستخرجا ذو جذر واحد لتقييم فعالية إزالة الطبقة السميكة. تم حساب وجود الطبقة السميكة في الثلث الأوسط من قناة الجذر باستخدام الميكروسكوب الليزري الماسح الضوئي الحويصلي. ثم تم إجراء النشاط المضاد للبكتيريا على نوعين من البكتيريا باستخدام طريقة تشتت الأغار.
وجدنا أن التراكيز 2,5% و 5% من المغلي أكثر فعالية بشكل ملحوظ في إزالة الطبقة السميكة، ومع ذلك، لم يتم ملاحظة فرق ملحوظ عند المقارنة مع المادتين الأخريين. أظهرت نتائج اختبار المضادات الحيوية المختبرية أن خمسة بالمائة من المغلي يظهر نشاطا مضادا للميكروبات أعلى ضد كلا المسارين التجريبيين.
تشير هذه النتائج إلى أن مغلي أوراق الشجرة يمكن اعتباره محلولا فعالا في علاج الجذور.
This study evaluated the effectiveness of moringa (Moringa oleifera) leaves decoction for removing a smear layer compared to sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA), as well as its antimicrobial activities.
The moringa leaves were extracted using hot water decoction at two different concentrations (2.5% and 5.0% w/v). A total of 30 extracted human single-rooted teeth were prepared to assess the smear layer removal efficacy. The presence of a smear layer in the middle third of the root canal was detected by confocal microscopy. Then the antibacterial effects were assessed against Enterococcus faecalis and Streptococcus mutans bacteria using the agar diffusion method.
The 2.5% and 5.0% decoction were significantly more effective than 0.25% NaOCl in removing the smear layer (p < 0.05); however, no significant difference was observed compared to EDTA (p > 0.05). The in vitro antimicrobial assay showed that 5.0% decoction had higher antimicrobial activity against both of the test pathogens.
The findings of this study suggest that moringa leaves decoction can be considered an effective irrigant in endodontics.
Pulp Out, paste-contained jatropha sap, sidaguri roots, and melittin, has been studied to have potency used as an herbal-based devitalizing agent. Prior to clinical application, the toxicity of Pulp ...Out should be evaluated as it might leak from the cavity unintentionally and get into the digestive systems, which can cause either local or systemic effects. The present study aimed to evaluate the impact of Pulp Out application on periodontal and periapical tissue as well as acute toxicity in Wistar rats. The paste was inserted into the periapical tissue. After 7 days, the periapical tissue was isolated for histopathological evaluation. Pulp Out in an oral suspension of 50, 500 and 2500 mg/kg BW was administered. Autonomic nerve signs were observed intensively every 4 h as well as water and food consumption for 14 days. Biochemical, hematologic parameters and specific organs were evaluated. Therefore, considering the inflammatory lymphocyte cells, osteoblasts, and osteoclasts, Pulp Out is not toxic. The acute toxicity study revealed no treatment-related death was observed, indicating that LD50 is greater than 2500 mg/kg BW. No significant difference statistically either in body weight, water or food consumption as was observed in autonomic clinical signs of treated groups when compared to the control. Similarly, biochemical and hematologic properties showed no significant difference compared to control. Histopathological, slightly hydrophilic degenerative was observed in all organs. In conclusion, Pulp Out showed low acute toxicity in Wistar rats.
Introduction: The effect of bleaching on tooth structure is the loss of interprismatic substance which causes prism irregularities and changes in enamel morphology such as increased porosity and ...demineralization. This can be stopped by encouraging remineralization if the pH is neutralized and there are enough calcium and phosphate ions in the oral cavity. One agent that can be used to help the remineralization process is nano hydroxyapatite (nHA) which is a bioactive and biocompatible material for the natural mineral enamel. This study aims to determine change in the percentage of porosity, calcium, phosphate and hydroxyapatite synthesized from blood clam shells (Anadara granosa) and CPP-ACP as a positive control. Material and methods: The research design was a pre-post test control group design. Six maxillary first premolars were cut to the CEJ with a size of 5x5x2 mm then 40% hydrogen peroxide was applied. The first group was applied nHA synthesized from blood clam shells and the second group was applied CPP-ACP. Determination the percentage of porosity, calcium, phosphate and hydroxyapatite was carried out before and after bleaching and after aplication of remineralizing agent. Results: The study showed an decrease the porosity, calcium, phospate and increase hydroxyapatite precentage after sampel was applied to the remineralizating material nHA synthesized from blood clam shells and CPP-ACP. Conlusion: nHA results of blood clam shell synthesis has the potential to be used as an enamel remineralization agent after in-office bleaching. Key words: Blood clam shell, Casein Phosphopeptide-Amorphous Calcium Phosphate, In-office bleaching, Nano Hydroxyapatite
Objective: To evaluate the microhardness and porosity of the dentin of Wistar rats after pulp-out application.
Materials and Methods: This was laboratory experimental research with posttest design ...with control group. Twelve teeth of wistar rats were allocated into 2 groups, the test group and the control group. In the test group, teeth were prepared on the labial surface until half thickness of the dentin, then pulpout was applied to the base of cavity, covered with GIC. On the 7th day, euthanasia and extraction were performed to test the dentin microhardness with Vickers Hardness Tester and dentin porosity with Laser Scanning Microscope (LSM).
Results: The mean value of tooth hardness after pulp-out application was 22.23 ± 3.51 HV while the mean value of the control group was 27.70 ± 1.70 HV, with p value = 0.31 at 95% significance level. There was a decrease in tooth hardness of treated sample which was not significantly different compared to the control group. CLSM photo shows white lines on the sample surface as the exposed dentinal tubules with a higher intensity compared to the control group.
Conclusion: Pulp-out decreased tooth microhardness and cause porosity of the teeth.
Background: Pulp wound healing is a critical aspect of endodontics, aiming to preserve the vitality and function of dental pulp tissues. Natural compounds have gained attention for their potential ...therapeutic applications in dentistry. Mauli banana (Musa acuminata) is a tropical fruit in South Kalimantan as one of the natural plants that have the ability as antibacterial, antifungal, anti-inflammatory, antioxidant, and immunomodulatory effects contains various bioactive molecules with potential pulp wound healing properties. Purpose: to identify and evaluate the functional groups present in mauli banana stem extracts. Methods: This study is true experimental research, the samples were mauli banana stem that were extracted with maceration technique and were subjected to Fourier-Transform Infrared Spectroscopy test. Results: Identification of functional groups of organic compounds from mauli banana are as follows: a) Peak 3638.95 cm-1 show O-H (nonbonded hydroxy group, OH stretch primary) component alcohol, b) Peak 3265.82 cm-1is C-H (alkane), c) Peak 2928.09 cm-1 refer to OH (carboxylic acid hydrogen bonds) and aldehydes groups, d) peak 1571.35 cm-1 refers to amide, C=O - asymetric stretching, e) peak 1400.82 cm-1, refers to CO2- symetric stretching and carboxylate (carboxylic acid salt) CH2 scissoring, f) peak 1030.17 cm-1 refers to C=C (alkanes), aliphatic phosphate, g) Peak 520.53 cm-1 refers to inorganic phosphates. Conclusion: FTIR spectra analysis of mauli banana stem extract show the presence of O-H hydroxy groups, aldehydes groups, carbonyl groups, aliphatic groups, carbonyl groups, amides groups and C-O stretching vibrations suggests that the extract contains various bioactive molecules with potential pulp wound healing properties.
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